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Triple-action magnesium for digestion, sleep, mood & more.*
✔ Eases stress, tension, and brain fog*
✔ Promotes regular, comfortable digestion — fast*
✔ Strengthens bone density and cardiovascular health*
✔ Calms the nervous system & supports deep, uninterrupted sleep*
✔ Delivers 3 highly absorbable forms of magnesium*
✔ Doctor-developed and gentle enough for daily use*
Maximize Your Results: Pair with ProBRAINBiotics and PreBRAINBiotics to optimize digestion, gut health, and mood through the gut-brain axis.*
Over 50% of Americans don’t get enough magnesium and your brain feels it.*
Poor sleep, stress, brain fog, low energy, and irregular digestion could be signs your body is running low on magnesium.*
Smart Magnesium delivers the three most absorbable forms of magnesium — malate, citrate, and glycinate — in one doctor-developed formula to support calm, clarity, regularity, and deeper sleep.*
Gentle on the gut, powerful for the brain, and essential for over 600 enzyme functions in the body.*
USE: Take 2 capsules daily with food. For best results, use consistently as part of your daily routine.*†
EARLY RESULTS: Notice improved digestion and relaxation within the first 1–2 weeks.* Smart Magnesium starts working quickly to relieve tension, support regularity, and promote a more balanced mood.*†
LONG-TERM BENEFITS: With daily use, Smart Magnesium helps maintain healthy magnesium levels to support deeper sleep, stronger bones, cardiovascular health, and mental clarity over time.*†
*†Results may vary based on individual health and fitness levels. Consistent use, in conjunction with a healthy lifestyle, is recommended.
Support Your Brain, Sleep & Digestion
Smart Magnesium delivers three of the most absorbable forms of magnesium—malate, citrate, and glycinate—for targeted support your brain and body can actually feel.*
✔ Magnesium Malate: Fuels cellular energy and helps combat fatigue. Supports muscle performance and eases occasional tension without discomfort.*
✔ Magnesium Citrate: Promotes smooth, regular digestion while supporting optimal hydration and electrolyte balance. Gentle on the gut, fast-acting for results you can feel.*
✔ Magnesium Glycinate: Calms the nervous system, promotes deeper, more restful sleep, and supports mood balance through healthy GABA activity.*
Smart Magnesium: Triple-action magnesium for digestion, sleep, mood & more*
✔ Eases stress, tension, and brain fog*
✔ Promotes regular, comfortable digestion - fast*
✔ Strengthens bone density and cardiovascular health*
✔ Calms the nervous system & supports deep, uninterrupted sleep*
✔ Delivers 3 highly absorbable forms of magnesium*
✔ Doctor-developed and gentle enough for daily use*
| Supplement Facts | ||
|---|---|---|
| Serving Size: 2 Capsules Servings Per Container: 60 |
||
| Amount Per Serving | % Daily Value | |
| Magnesium (as glycinate, citrate, malate) |
300 mg | 71% |
| Other Ingredients: Hypromellose, rice hull extract, ascorbyl palmitate. | ||
Week 1


Gentle Digestive Support Begins
Magnesium citrate helps promote regularity and supports digestive comfort.*
Weeks 2-3


Calm and Clarity Take Shape
Magnesium glycinate begins supporting relaxation, focus, and balanced mood.*
Weeks 4 & Beyond


Steady Energy, Rest, and Resilience
Ongoing use supports healthy sleep, energy production, bone strength, and overall vitality.*
Even if you meet—or exceed—the government-recommended amount of daily servings of fruits and vegetables, you may still have nutrient deficiencies due to factors like genetics, stress, toxic exposures from other people's smoking or from other environmental pollutants, nutrient depletion by certain medications you may be taking, and consumption of alcohol. Cover your nutritional bases with the best doctor-developed, comprehensive multivitamin, multi-mineral supplement on the market.
Made by combining clinically researched brain boosters with optimally absorbed vitamins, essential minerals, other essential nutrients, conditionally essential nutrients, organically grown vegetable and fruit concentrates, beneficial herbal ingredients, and digestive enzymes to assist with their utilization, NeuroVite Plus offers an unmatched broad spectrum of nutrients and herbals to help your body and brain function at their best.
NeuroVite Plus packs in over 1000% more of certain nutrients than the recommended Daily Value set forth by the FDA. That’s because unlike other companies, we based the levels of active ingredients used in our multivitamin on the daily dosing shown effective in clinical trials, not minimum amounts recommended to prevent deficiency. Research shows there is a huge dosing gap between preventing deficiency and experiencing measurably better health. Here at BrainMD, we aim for better health.
Unlike other multivitamins, NeuroVite Plus contains a number of powerful nutrients clinically researched for better brain function.
PhosphatidylSerine (PS) The only nutrient granted two qualified health claims by the U.S. FDA related to its brain benefits.
Acetyl-L-Carnitine (ALC) Assists the brain in the production of the important neurotransmitter acetylcholine.
Alpha-Lipoic Acid (ALA) Clinical trials indicate that ALA can enhance nerve cell structure and function.
NeuroVite Plus combines more than 50 nutrients and plant extracts in their most active forms to give you whole body-mind nutrition in a way that drugstore multivitamins cannot do. It contains three of Dr. Amen’s hand-selected proprietary high-nutrient blends:

Magnesium citrate is one of the most clinically studied forms, shown to offer significantly higher bioavailability than other forms of magnesium.* It acts as a gentle osmotic laxative, promoting smooth, comfortable digestion without harsh effects.* It also contributes to improved muscle relaxation and plays a role in over 600 metabolic reactions across the body.*

Magnesium glycinate is bonded to glycine an amino acid that helps regulate GABA, a key calming neurotransmitter.* This form is especially effective for nervous system relaxation and has been studied for its role in improving sleep quality and reducing serious mood issues.* One clinical trial reported rapid improvements in mood within 7 days using a combination of glycinate and taurinate forms.*

Formed with malic acid, this highly bioavailable form of magnesium supports ATP production and is often used to ease tension, headaches, and digestive irregularities.* Clinical studies in both humans and animals suggest that magnesium malate has superior absorption and stays active longer than many other forms making it ideal for daily use without digestive discomfort.*


Magnesium is one of the most important minerals in the human body, supporting 600+ enzymatic reactions.*
It impacts how you think, sleep, digest, move, and manage stress yet over half of American adults don’t get enough from diet alone.*
When your magnesium levels are low, it can show up as:
Smart Magnesium is doctor-formulated with the three most effective forms of magnesium malate, citrate, and glycinate to fuel the systems your brain and body rely on every day.*


Most magnesium supplements offer just one form, limiting how much your body can actually absorb and use.*
Smart Magnesium delivers more with 3 complementary, clinically studied forms in every dose.*
✔️ Magnesium Malate fuels cellular energy and helps fight physical and mental fatigue.*
✔️ Magnesium Citrate promotes bowel regularity and smoother digestion.*
✔️ Magnesium Glycinate supports deep, restorative sleep and elevates mood.*
This clinically-backed formula is gentle on the gut, safe for daily use, and designed for real, noticeable results.*
Because when your magnesium works smarter, so do you.*
- Claire R., Verified Buyer


From the moment you wake up to the time you fall asleep, magnesium is working behind the scenes to regulate mood, ease tension, support digestion, and help you recharge overnight.
But most people don’t get enough, and even a mild deficiency can leave you feeling foggy, fatigued, or off balance.*
Smart Magnesium delivers what your system actually needs: Three highly absorbable forms your brain and body can’t do without.*
- Daniel G. Amen, MD


Most people wait until everyday discomfort starts to interfere with the things they love.
But true comfort begins within—when your brain and body work in harmony to handle daily stress and movement challenges.
Smart Relief is designed to support healthy communication between your brain and body, helping you stay balanced, comfortable, and active every day.*
By taking it consistently, you’re helping your body adapt to everyday physical stressors and maintain greater ease of movement over time.*
Because it’s formulated for daily use, the benefits build, helping you feel more comfortable, resilient, and ready for whatever the day brings.*
If you’re ready to support lasting comfort and flexibility, start your Smart Relief routine today.*


We stand behind Smart Relief with a 100% Happiness Guarantee.
If you don’t love it for any reason, return it within 30 days for a full refund—no questions asked.
Just call or email our support team within 30 days of your purchase and we’ll make it right.
Refunds exclude original shipping costs. Applies to purchases made directly through BrainMD.com.
Razzaque MS. Magnesium: Are We Consuming Enough? Nutrients. 2018;10(12):1863. Published 2018 Dec 2. doi:10.3390/nu10121863.
Uysal N, Kizildag S, Yuce Z, et al. Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? Biol Trace Elem Res. 2019;187(1):128-136. doi:10.1007/s12011-018-1351-9.
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AlSamman MA, Leung S, Moustafa A, Abeid M, Baird GL, Shah SA. Adequacy Rate of Magnesium Citrate Bowel Preparation in a Large Retrospective Cohort. R I Med J (2013). 2022;105(2):46-50. Published 2022 Mar 1.
Arab A, Rafie N, Amani R, Shirani F. The Role of Magnesium in Sleep Health: A Systematic Review of Available Literature. Biol Trace Elem Res. 2023;201(1):121-128. doi:10.1007/s12011-022-03162-1.
Zhao S, Hu J, Yue C, Tian J, Zhou S, Zhu Q. Dietary Magnesium Intake Is Associated With Self-Reported Short Sleep Duration but Not Self-Reported Sleep Disorder. Brain Behav. 2025;15(2):e70251. doi:10.1002/brb3.70251.
Rajizadeh A, Mozaffari-Khosravi H, Yassini-Ardakani M, Dehghani A. Effect of Magnesium Supplementation on Depression Status in Depressed Patients With Magnesium Deficiency: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrition. 2017;35:56-60. doi:10.1016/j.nut.2016.10.014.
Eby GA, Eby KL. Rapid Recovery From Major Depression Using Magnesium Treatment. Med Hypotheses. 2006;67(2):362-370. doi:10.1016/j.mehy.2006.01.047.
Jackson SE, Smith L, Grabovac I, Haider S, Demurtas J, López-Sánchez GF, Soysal P, Redsell S, Isik AT, Yang L. Ethnic Differences in Magnesium Intake in U.S. Older Adults: Findings From NHANES 2005–2016. Nutrients. 2018;10(12):1901. doi:10.3390/nu10121901.
UCLA Health. Are You Getting Enough Magnesium? Published June 23, 2023. Accessed May 25, 2025.
Harvard T.H. Chan School of Public Health. Magnesium. The Nutrition Source. Updated May 2025. Accessed May 25, 2025.
Dr. Amen discusses his most potent nutritional weapon for a top-performing body and mind