Father's Day Sale! 15% Off + FREE SHIPPING | Code: DADSDAY15
Dark purple supplement bottle with white capsules at the base against a light purple background.
BrainMD Restful Sleep: infographic, brief phrases highlighting the product's benefits set against a light purple background
BrainMD Restful Sleep: blurry image of a smiling woman in background, purple supplement bottle on nightstand in foreground
BrainMD Restful Sleep: infographic, images, names & descriptions of 5 key ingredients set against a purple background
BrainMD Restful Sleep: infographic, woman's hands holding purple supplement bottle with customer review on the side
BrainMD Restful Sleep: infographic, supplement facts box
Best Seller

Restful Sleep

Restful Sleep

Fall asleep faster and stay asleep longer with 2.5 mg melatonin*

Subscribe & Save
One-time purchase

Description

Can't fall or stay asleep? Restful Sleep by Dr. Daniel G. Amen is for anyone who's tired of staring at the ceiling at 2 AM. This advanced sleep supplement combines 2.5 mg of melatonin with calming nutrients like GABA, valerian, and vitamin B6 to gently ease your body into deep, uninterrupted sleep, without leaving you groggy the next day.*

Whether your sleep cycle is out of sync, your brain won't shut off, or you just need serious sleep support, this doctor-developed formula helps reset your rhythm and restore truly restful sleep.* Safe for nightly use, fast-acting, and non-habit forming, it works the first night and keeps working better over time.*

  • Free Shipping on Orders $75+
  • Subscribe & Save up to 25% + Free Shipping
  • 100% Money Back Guarantee

Key Benefits

Sleep

Relaxation

Calm

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.
Vegan
Gluten Free
Soy Free
Vegan
Gluten Free
Soy Free

GABA

375 mg
Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the brain’s primary calming neurotransmitter.* It works by slowing down excessive neural activity, helping to reduce feelings of anxiousness, tension, and overstimulation.* By activating the brain’s “off switch,” GABA supports a relaxed mental state, eases racing thoughts, and promotes emotional balance.* This calming effect can enhance focus, improve sleep quality, and support the body’s natural stress response for overall mental well-being.*

Magnesium

50 mg
Magnesium is a vital mineral needed by every cell in the body, especially for the brain’s nerve cells to communicate effectively.* It supports the electrical signals that allow neurons to connect and process information.* Often called “the relaxation mineral,” magnesium helps regulate muscle tension, hydration, and energy production.* It also balances stress hormones like adrenaline and helps improve sleep quality.* By promoting calmness and mental focus, magnesium plays a key role in supporting emotional well-being, cognitive function, and overall physical health.*

Vitamin B6

10 mg
Vitamin B6, provided as both pyridoxine and its active form pyridoxal-5-phosphate, is essential for brain and metabolic health.* It supports over 100 enzyme reactions involved in producing neurotransmitters like serotonin and dopamine, which help regulate mood, focus, and relaxation.* B6 also plays a key role in metabolizing carbohydrates, fats, and proteins for energy, and helps convert homocysteine—a potentially harmful compound—into beneficial antioxidants.* This dual-form formula ensures optimal absorption and effectiveness for nervous system support and overall well-being.*

Valerian Extract

300 mg
Valerian root is a traditional herb long used to promote relaxation and better sleep.* It is believed to work by interacting with GABA receptors in the brain—key pathways that help calm nervous system activity and ease mental tension.* By supporting the body’s natural calming mechanisms, valerian helps reduce the time it takes to fall asleep and encourages deeper, more restorative rest.* It’s especially useful for promoting sleep quality without the grogginess often associated with sleep aids.*

Melatonin

2.5 mg
Melatonin is a naturally occurring hormone produced by the brain in response to darkness, helping regulate your internal sleep-wake cycle.* It signals to the body that it’s time to wind down, supporting the natural transition to sleep.* Factors like aging, travel across time zones, and certain medications can reduce melatonin levels, disrupting sleep patterns.* Supplementing with melatonin can help restore healthy circadian rhythms, promote faster sleep onset, and improve overall sleep quality—supporting more restful and consistent sleep.*

Supported by Clinical Research

Vitamin B6 May Help Mitigate Sleep Deprivation and Improve Sleep Quality
Animal study and population-based research

Vitamin B6 was shown to counteract cognitive decline caused by sleep deprivation and is associated with reduced risk of sleep-related issues in general populations.
(Yuan 2024)
(Ge 2022)
BrainMD
Extra-Strength Sleep Support*

Say Goodbye To Restless Nights*

If you’ve ever stared at the ceiling, watching the hours slip away, you know poor sleep doesn’t just make you tired—it affects your mood, memory, focus, and even your physical health.*

Restful Sleep is your nightly reset button. Combining 2.5 mg of melatonin to naturally align your sleep cycle with calming nutrients like GABA, valerian root, and vitamin B6, this formula works with your body’s natural sleep signals to help you:

✔ Fall asleep faster*

✔ Stay asleep longer*

✔ Wake up clear-headed and energized*

Unlike many sleep aids, Restful Sleep is non-habit forming, gentle enough for nightly use, and designed to improve your sleep quality the longer you take it.*

Expert Reviews

“While you’re sleeping, your brain is hard at work eliminating the toxins that build up during the day. Restful Sleep helps you stay asleep throughout the night, so your brain can perform this critical nightly routine.”

Dr. Daniel Amen

Founder, BrainMD & Amen Clinics
"Deep, restorative sleep is the foundation of mental and physical health. Restful Sleep is formulated to help you fall asleep faster, stay asleep longer, and wake up ready to take on the day without dependence or next-day grogginess. My wife and I use Restful Sleep on the days we are over-focused and need a little help winding down because it’s safe and NON_ADDICTIVE."

Dr. Rich Friedel, PhD, DM

Elite Brain Health Professional, of Friedel Clinic
"This formula combines targeted nutrients to support your body’s natural sleep processes. It’s a smart, science-based approach that addresses the underlying reasons you can’t sleep, rather than just masking the problem."

Dr. Jonny Bowden PhD, CNS

Board Certified Nutrition Specialist
"Restful Sleep is an excellent supplement that helps you to not only fall asleep but also stay asleep."

Dr. Srikanth Prayaga, MD

Child, Adolescent, & Adult Psychiatrist
"This tried-and-true BrainMD supplement is my go-to for sleep and has been successful with some of the most stubborn cases of insomnia I’ve worked with!"

Linda Long, NP

Brain health and clinical neuroscience specialist, board-certified nurse practitioner
BrainMD
Better Sleep, Backed By Science*

Why Restful Sleep Works When Others Don’t*

Most over-the-counter sleep products rely on high doses of melatonin that can leave you groggy. Restful Sleep’s precise 2.5 mg dose is just enough to trigger your body’s natural sleep cycle—without the morning fog.*

Then, our brain-calming blend goes to work:

✔ GABA: Promotes relaxation and helps quiet mental chatter so you can drift off peacefully.*

✔ Valerian Root: Used for centuries to improve sleep quality and duration.*

✔ Vitamin B6: Supports the production of serotonin and melatonin, your body’s sleep and mood regulators.*

This balanced formula addresses both the mental and physical causes of sleeplessness, helping you reset your rhythm for better nights and brighter days.*
BrainMD

What To Expect

Night 1

Clinical‑strength melatonin (2.5 mg) combines with GABA, magnesium, and valerian to help quiet the mind and ease you gently into deep sleep.*
Week 1

As your body adapts, your sleep becomes more uninterrupted. Users commonly report fewer mid‑night wake-ups and waking up feeling more refreshed.*
Week 2–4

Vitamin B6 supports natural neurotransmitter production, while magnesium and valerian aid muscle relaxation. Together, they support a deeper, more balanced sleep cycle promoting a clearer, more energetic morning.*
4 Weeks+

Consistent nightly use helps recalibrate your circadian rhythm, so your body can enter restorative sleep more naturally.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

BrainMD

How do I take Restful Sleep?

Take 1-4 capsules of Restful Sleep 30-60 minutes prior to desired bedtime or as directed by your healthcare professional.*

Overall rating: 4.2714057 / 5 from 619 reviews.

AI Generated Review Summary

Restful Sleep by Dr. Daniel G. Amen is a sleep supplement that combines melatonin with calming nutrients to help users achieve deep, uninterrupted sleep without grogginess. Customers report feeling relaxed and well-rested, with many praising the product's effectiveness and immediate results. The supplement is safe for nightly use and works better over time.

Summary topics

  • Brain Calming: 2%
  • Product Results: 4%
  • Pill Effectiveness: 3%
  • Sleep Quality: 45%
  • Supplement Effectiveness: 8%

Review topics: ["results","quality","feel","difference","works","sleep","supplement","vitamins","capsules","stay","mind","combination"].

Review highlights

  • "I recommend restful sleep 100% , no side effects!" — Laura
  • "We love the calming factor as well as the two types of melatonin (fast acting and delayed)." — Toni
  • "The effects for me were immediate and wonderful." — Brenda

Reviews

Restful Sleep

"I didn’t have good results until I took 3 each evening. I started with 2 for a long time but I need 3. Now I’m sleeping well! Barbara Palmer"

— Barbara P. (5/5)

I am currently enjoying taking

"I am currently enjoying taking restful sleep and am noticing that when I wake up to use the restroom in the middle of the night I am able to get right back to sleep again. This has solved that annoying problem for me! I do combine it with a vitamin D 10,000 iu, NAC 1400mg, 2 tart cherry capsules and a B complex (25mg-100mg as needed). This vitamin cocktail has taken me from 3-4 hrs of sleep per night to 6-7 per night and am feeling more rested now."

— Jennifer C. (5/5)

Helpful in combination with other products

"I use restful sleep in conjunction with L-theanine. I fall asleep easily but I don't stay asleep. This combination has been the most effective for me. If I gave multiple bad nights I'll add a Tylenol PM in the mix. I try to do this as rarely as possible. I know another person that uses Calm my brain and that works well for them. We're all different so it takes some process to figure out what works for you."

— Scott H. (4/5)

Works well

"I feel like I wake up rested after a night of deep restorative sleep"

— Sarah E. (5/5)

I feel grateful groggy after, but it gets me to sleep.

"I feel grateful groggy after, but it gets me to sleep."

— Denise K. (4/5)

Restful Sleep. . . Yes!

"Works for me. Tastes good. Helps me achieve calm and fall asleep easier."

— Lake E. (5/5)

Restful Sleep

"Restful Sleep is another great supplement. It also helps with sleeplessness. Highly recommended."

— Norma M. (5/5)

I slept well

"I slept well"

— Mary W. (5/5)

Great sleep aid without the Grogginess

"When I need a good nights sleep, I take the Restful Sleep supplement. It always works, and I do not experience any grogginess the next day, which I have experienced with other sleep supplements. So definitely a Winner. ."

— Shanti G. (5/5)

Sleepy time

"Restful sleep does seem to help me get to sleep faster."

— Lorraine R. (4/5)

Q&A