Purple supplement bottle with white capsules at the base against a dark blue background.

BrainMD Stress Relief Sleep Supplement benefits - promotes healthy stress response, improves sleep quality, lowers cortisol

BrainMD Stress Relief Sleep Supplement comparison to alternative brands.

BrainMD Stress Relief Sleep Supplement backed by clinical studies and designed by brain experts

BrainMD Stress Relief Sleep Supplement customer testimonial

BrainMD Stress Relief Sleep Supplement main ingredients and how they help you sleep better

BrainMD Stress Relief Sleep Supplement - Infographic on how Stress Relief Sleep Supplement helps you sleep better

New ArrivalMelatonin Free

Stress Relief Sleep

Name: Stress Relief Sleep
Brand: BrainMD by Daniel Amen, MD
SKU: 1194
Price: 39.95 USD
Availability: InStock
Rating: 4.8 (28 reviews)

Fast-acting, melatonin-free formula designed to lower cortisol for better sleep*

Subscribe & Save

1 Unit every month

15% Off Save $5.99

$33.96 Each

6 Units every 6 months

25% Off Save $9.98

$29.97 Each

3 Units every 3 months

20% Off Save $7.99

$31.96 Each

One-time purchase

1 Unit one-time delivery

$39.95

Description

Can't turn your brain off at night or too stressed to sleep?

Stress Relief Sleep is a fast-acting, melatonin-free formula that helps your brain and body fully relax so you can fall asleep, stay asleep, and wake up feeling like yourself again.*

No hormones. No grogginess. No habit-forming ingredients, just calm, restorative sleep.*

In clinical studies of KSM-66® Ashwagandha, the cutting-edge adaptogen in Stress Relief Sleep, cortisol levels dropped by up to 28% and 77% of participants reported feeling less anxiousness in just 60 days.*

In a separate study, 49% of participants with severe sleep issues reported significant improvements in sleep quality after only 10 weeks!*

Benefits

✔ Helps your brain and body fully unwind after a high-stress day*

✔ Supports healthy cortisol levels for deeper, uninterrupted sleep*

✔ Fast-acting—feel the calming effects in just 30–60 minutes*

✔ Melatonin-free, non-habit forming, and 100% natural*

✔ Formulated by top brain health and sleep experts*

How to use

USE: Take 3 capsules with water 30–60 minutes before bedtime, or as directed by your healthcare provider. Not for children or those who are pregnant or breastfeeding.*

EARLY RESULTS: Noticeable feelings of calm and relaxation in under an hour!* Most users notice improved sleep within the first 1–2 nights.*†

LONG-TERM BENEFITS: Daily use supports stress, mood, and feelings of anxiousness—typically within 1 to 4 weeks.*†

*†Results may vary based on individual health and fitness levels. Consistent use, in conjunction with a healthy lifestyle, is recommended.

DOCTOR’S RECOMMENDATION: Take with NeuroVite Plus Multivitamin and Omega-3 Power for optimal sleep quality and peak brainpower.*

Ingredients

KSM-66® Ashwagandha
L-Theanine
GABA (Gamma-Aminobutyric Acid)
Magnesium (as magnesium bisglycinate and magnesium malate)

Free Shipping on Orders $75+
Subscribe & Save up to 25% + Free Shipping
100% Money Back Guarantee

Key Benefits

Relaxation

Sleep

Stress Support

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.

Magnesium

150 mg

Magnesium is a vital mineral needed by every cell in the body, especially for the brain’s nerve cells to communicate effectively.* It supports the electrical signals that allow neurons to connect and process information.* Often called “the relaxation mineral,” magnesium helps regulate muscle tension, hydration, and energy production.* It also balances stress hormones like adrenaline and helps improve sleep quality.* By promoting calmness and mental focus, magnesium plays a key role in supporting emotional well-being, cognitive function, and overall physical health.*

KSM-66® Ashwagandha Root Extract

600 mg

Ashwagandha (Withania somnifera), especially in its clinically studied KSM-66®️ form, is a powerful adaptogenic herb used for centuries in Ayurvedic and traditional medicine.* It helps the body adapt to physical and mental stress by supporting balanced cortisol levels, promoting calm, and enhancing focus.* Research shows that ashwagandha may improve memory, attention, and mental clarity, while also reducing occasional anxiousness and supporting restful sleep.* Its wide-ranging benefits make it a natural choice for promoting emotional resilience, cognitive performance, and overall well-being.*

L-Theanine

300 mg

L-theanine is a calming amino acid naturally found in green tea and widely studied for its stress-reducing effects.* It promotes the production of alpha brain waves, which are linked to a relaxed but alert mental state.* L-theanine helps ease tension and supports a sense of calm without causing drowsiness.* It also contributes to healthy blood pressure regulation, especially during times of stress.* Ideal for promoting focus and emotional balance, l-theanine is a natural way to stay calm, clear-headed, and resilient throughout the day.*

GABA

300 mg

Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the brain’s primary calming neurotransmitter.* It works by inhibiting excessive neural activity, helping to regulate stress responses and promote mental relaxation.* By supporting the brain’s “off switch,” GABA helps quiet racing or anxious thoughts, allowing the mind to settle.* This can lead to improved focus, a more balanced mood, and better sleep quality, making GABA an important nutrient for emotional well-being and overall mental calm.*

BrainMD Stress Relief Sleep: root and leaf sources for powder and capsule supplements

Supported by Clinical Research

Magnesium Supplementation May Support

Stress Relief and Overall Wellbeing

Review and clinical studies on stress, mood, and health benefits

Magnesium plays a role in regulating the stress response, promoting relaxation, and supporting cardiovascular and metabolic health.

(Bekstrand 2011)

(Boyle 2017)

(Al-Alawi 2018)

Ashwagandha May Help Reduce Stress and Improve Resilience

Randomized, placebo-controlled trials and review

Ashwagandha root extract has demonstrated anxiolytic and adaptogenic effects, helping reduce stress, improve sleep, and enhance well-being.

(Chandrasekhar 2012)

(Salve 2019)

(Mikulska 2023)

GABA May Promote Relaxation and Better Sleep

Clinical and mechanistic studies on stress and sleep regulation

Supplemental GABA has been shown to reduce stress-related symptoms and may play a role in sleep quality and calming the nervous system.

(Hepsomali 2020)

(Gottesmann 2002)

BrainMD Stress Relief Sleep: woman opening a bottle of supplements

Calm Your Mind, Rest Your Brain

Finally, Fall Asleep & Stay Asleep

Stress doesn’t stop when your head hits the pillow and when it hijacks your sleep, your brain pays the price.* High cortisol doesn’t just delay sleep, it disrupts memory, focus, mood, and recovery.* And poor sleep? It sends cortisol even higher.* That’s why Stress Relief Sleep is designed to reset the cycle -fast.*

With clinically studied ashwagandha, magnesium, GABA, and l-theanine, this brain-targeted sleep supplement helps you calm down, fall asleep, and stay asleep, naturally.*

✔ Fall asleep faster*

✔ Stay asleep longer*

✔ Wake up feeling clear, not cloudy*

“Stress and poor sleep are two of the biggest threats to brain health. Stress Relief Sleep is designed to calm the brain, lower cortisol, and help you get the restorative sleep your brain needs to perform at its best.”

"Many of my patients can’t sleep because their stress hormones are too high at night. Stress Relief Sleep addresses this directly by lowering cortisol naturally, without melatonin,so you can relax, fall asleep faster, and wake up feeling refreshed."

"I recommend Stress Relief Sleep to patients who want better sleep without the grogginess of traditional sleep aids. By targeting the stress response, it not only improves sleep but also supports emotional well-being."

"This formula is unique because it combines clinically studied ashwagandha with magnesium, GABA, and L-theanine nutrients I often recommend separately for relaxation and sleep quality. Together, they provide a comprehensive, non-habit-forming way to reset your stress and sleep cycle."

"When cortisol stays elevated at night, it disrupts deep sleep cycles and impairs brain repair. Stress Relief Sleep’s evidence-based ingredients help quiet the mind and promote the kind of restorative sleep essential for long-term cognitive health."

BrainMD Stress Relief Sleep: close-up image of capsules with white powder against a blue background

Lower Nighttime Cortisol

Stop The Stress-Sleep Cycle - Fast

Tired but wired? That’s cortisol, your body’s primary stress hormone, flooding your system and keeping your brain stuck in high alert mode.* When cortisol stays elevated at night, it:

✔ Delays sleep onset*

✔ Disrupts deep sleep cycles*

✔ Increases feelings of anxiousness and next-day exhaustion*

Stress Relief Sleep is clinically formulated to reset that cycle - fast.*

BrainMD Stress Relief Sleep: woman stretching after a night of restful sleep

What To Expect

30–60 - Minutes Calming Onset

Calming Onset
Ingredients like L-theanine and magnesium start working quickly to relax the nervous system. Many feel their mind slowing down, tension easing, and an easier transition into sleep the very first night.*

Week 1 - Deeper, Less Restless Sleep

Adaptogens like Relora® and holy basil begin to regulate cortisol, helping you fall asleep more smoothly and stay asleep without frequent wakeups. Nights feel more restorative and mornings less groggy.*

Week 2–4 - Stress + Sleep Synergy

Consistent use compounds benefits: calmer evenings, better mood during the day, and more natural sleep rhythms at night. Many notice less stress reactivity overall, which carries into more restful nights.*

2–3 Months - Long-Term Balance

With continued use, Stress Relief Sleep helps maintain healthier cortisol patterns, deeper restorative sleep, and greater resilience to everyday stress. Over time, this means more energy, better focus, and improved emotional balance throughout the day.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

BrainMD Stress Relief Sleep: supplement bottle against a light yellow background

How do I take Stress Relief Sleep?

Take 2 capsules with water 1–2 hours before your desired bedtime. If you’re still feeling alert after an hour, you may take an additional capsule as needed.* This formula is not recommended for children, or for use during pregnancy or breastfeeding.* Always follow label directions or consult your healthcare provider before use.*

Why doesn’t Stress Relief Sleep contain melatonin?

Melatonin isn’t the only way to get better sleep—and for many people, it’s not the right one.* Stress Relief Sleep is melatonin-free by design. Instead, it uses clinically studied ingredients like KSM-66®️ Ashwagandha, L-theanine, GABA, and Magnesium to help lower cortisol and calm the brain naturally—without hormones, sedatives, or next-day grogginess.*

Is Stress Relief Sleep safe for children?

This supplement was formulated for adults and is not recommended for use in children.*

Can I become dependent on Stress Relief Sleep?

No. Stress Relief Sleep is a non-habit-forming dietary supplement—not a sedative or sleep drug.* It’s designed to support your body’s natural ability to relax and fall asleep by calming the brain and lowering cortisol.* You can take it nightly with confidence, knowing it works with your system—not against it.*

Will Stress Relief Sleep make me drowsy during the day?

Not at all. Stress Relief Sleep is formulated to promote deep, restful sleep without next-day drowsiness.* It contains no melatonin or sedative herbs—just research-backed nutrients that help calm the brain and lower cortisol, so you can sleep well and wake up sharp.*

Overall rating: 4.75 / 5 from 28 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["quality","improvement","feel","difference","works","sleep","supplement","grogginess"].

Review highlights

Reviews

Another Happy Customer--Good Sleep FINALLY!

"I purchased this sleep aid for a co-worker who I know has been struggling with trying to get good sleep for the ten years I have known him. He started seeing a difference in his sleep quality right away, and the ashwagandha hasn't even kicked in fully. I got this supplement for my 86 year-old mother and she now sleeps well. She occasionally takes the Put Me to Sleep supplement if she has a hard time falling asleep. I am so happy that this supplement works well for them!"

— Ronda (5/5)

Used to wake up too early

"I usually fall asleep quickly but would wake up after 5 or 6 hours feeling wide awake. I never got very much deep or REM sleep. Since taking this product, I average 7 hours per night and have more deep and REM sleep. I’m even remembering my dreams, which I haven’t done in a long time. I feel a little groggy upon awakening, but it doesn’t last long. It’s better than waking up feeling wired as I did before. This has really helped me."

— Nancy B. (5/5)

Stress Relief Sleep

"This Sleep product is the best !!! I fall asleep with in 30 minutes. I sleep through the night and wake up refreshed and ready to take on the day…I know it’s going to be a great day!"

— Beverly S. (5/5)

Good quality product

"I'm very satisfied with the quality of these products and how well they work"

— Carlos A. (5/5)

Stress Sleep

"This has been a really good additional supplement for me and allows me to fall asleep quickly and when I do wake up, it’s for a much shorter period of time and I’m able to go back to sleep more quickly. It’s also helping me get more days with larger amounts of deep sleep, and REM sleep. . still at work in progress"

— Deslys R. (5/5)

Impressed

"I have been a dopamine driven person my entire life which as led to several snow skiing accidents, car accidents and motorcycle accidents. Sleep is something that has escaped me for decades. I have averaged 3-5 hours a night for as long as I can remember. I had to solve this problem for serious health reasons. I started with Deep Comfort Sleep and things improved but still had interrupted sleep, I added Stress Relief Sleep to the mix and can now say I'm impressed with the results. Seven hours of consistent sleep with minimal interruptions. This is a great combination for me I'm 57 years old if that info is helpful to anyone. Thank you Dr. Amen and team."

— Stacy C. (5/5)

Rest full sleep

"These help me sleep without making me feel groggy in the morning."

— Joanna J. (5/5)

Helps Menopausal Sleep issues

"I monitor my sleep cycles with a biometric ring and Stress Relief Sleep has improve the quality and duration ofmy sleep"

— Joyce B. (5/5)

Quality sleep & awakening

"Since i’ve been taking this supp. i’ve noticed more dreams or more memory of dreams, sharper alertness or awakening in the morning and a lack of grogginess. It’s been beneficial!"

— Sean M. (5/5)

Melatonin free relief

"Great for evening wind down. Use this with other Dr Amen products. High quality and quick shipping."

— Beth O. (5/5)

Build Your Own Bundle

The Science Behind Brain Types

Not Sure Which Brain Type You Are?

Find Your Brain Type

What’s Your Stress Type?

Wake Up Feeling Refreshed

Build Your Own Bundle

Not Sure Which Brain Type You Are?

Stress Relief Sleep