But You Can Change How You Age.
Brain aging isn’t just about time. Signs of brain aging can speed up or slow down based on your lifestyle and nutritional status.*2
Fueling your brain with the right nutrients can help you stay sharp, clear, and resilient as you age.*2-4
Don’t let brain fog, memory lapses, or mental fatigue steal your spark.
At Every Age
Goal:
BUILD YOUR BEST BRAIN
Strategy:
Support focus, mental energy
& peak performance
Under 44
Goal:
PEAK PERFORMANCE
Strategy:
Optimize brain health now to
prepare for healthy aging
Over 44
Goal:
MAXIMIZE LONGEVITY
Strategy:
Support memory, cognition
& healthy brain aging
Foundational Brain Health Supplements
Clinically formulated to support brain function, mood, and mental energy at every stage of life.*
Supplements For Under 44: Early Adulthood
Shop targeted nutrients designed to optimize brainpower, productivity, and emotional resilience.*
Supplements For Over 44: Midlife & Beyond
Shop advanced nootropic formulas to support memory, mental clarity, and long-term cognitive health.*
Age Is Linear. Brain Health Isn’t.
Don’t let your brain age faster than you do.
300,000+ brain scans analyzed*
30+ years of clinical experience*
Published neuroimaging research*
Trusted by thousands*
Not Sure Where To Start?
Take Dr. Amen’s free Brain Health Assessment to get tailored supplement recommendations for your unique Brain Type and cognitive needs.*

Age With More Energy
Dr. Amen explains how to stop settling for “normal” and start optimizing your energy.
Frequently Asked Questions
Why is age 44 considered a turning point for brain aging?
Why is age 44 considered a turning point for brain aging?
Research published in the Proceedings of the National Academy of Sciences identified a nonlinear shift in brain metabolism around midlife, suggesting a "critical window" where targeted intervention may help support long-term brain health.*1 That's why Dr. Amen's supplement recommendations are split into "Under 44" and "44+" categories. The nutritional needs of your brain change as you approach this window.
Can brain aging be slowed down?
Can brain aging be slowed down?
While you can't stop the clock, research suggests the rate of brain aging is influenced by lifestyle and nutritional status, not just chronological age.*2,3 Supporting your brain with targeted nutrients, consistent habits, and gut-brain health may help you maintain sharper cognition and resilience over time.*
What supplements does Dr. Amen recommend for brain health?
What supplements does Dr. Amen recommend for brain health?
Dr. Amen's foundational brain health lineup includes NeuroVite Plus Multivitamin, Omega-3 Power, ProBrainBiotics MAX, Smart Creatine+, and Vitamin D3 + K2. They are formulated to support brain function, mood, and mental energy at every life stage.* For more targeted support, BrainMD also offers age-specific formulas for people under 44 (more focus and energy) and over 44 (memory and cognitive longevity).*
What's the difference between brain supplements for people under 44 vs. over 44?
What's the difference between brain supplements for people under 44 vs. over 44?
Supplements for under-44 adults, like Focus & Energy, Peak Energy, and NeuroLink, are designed to optimize productivity, mental energy, and emotional resilience during peak performance years.* Supplements for those 44 and older, like Brain & Memory Power Boost, Advanced Blood Flow, and Optimized CoQ10, are formulated to support memory, mental clarity, and long-term cognitive health as the brain ages.*
How do I know which brain supplements are right for me?
How do I know which brain supplements are right for me?
Dr. Amen offers a free Brain Health Assessment that takes less than 5 minutes and provides personalized supplement recommendations based on your unique Brain Type and cognitive needs. It's a quick way to get a tailored starting point instead of guessing which formulas fit your goals.*
About Daniel G. Amen, MD
Dr. Daniel Amen is a double board-certified psychiatrist, 20-time national bestselling author, and one of the most influential voices in brain health.
He is the founder of Amen Clinics, home to the world’s largest database of brain scans related to behavior, with 300,000+ scans and counting.
Through his research and clinical work, Dr. Amen has helped millions better understand how their brain impacts their mood, focus, memory, and overall well-being.
He created BrainMD to turn that science into targeted support for how your brain actually works.
References:
- Antal BB, van Nieuwenhuizen H, Chesebro AG, Strey HH, Jones DT, Clarke K, Weistuch C, Ratai E-M, Dill KA, Mujica-Parodi LR. Brain aging shows nonlinear transitions, suggesting a midlife “critical window” for metabolic intervention. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(10):e2416433122. doi:10.1073/pnas.2416433122.
- Zhang R, Yi F, Mao H, Huang Z, Wang K, Zhang J. Brain age gap as a predictive biomarker that links aging, lifestyle, and neuropsychiatric health. Communications Medicine. 2025;5:441. doi:10.1038/s43856-025-01100-5.
- Stoitsas K, Bakx P, Voortman T, Yu J, Roshchupkin G, Bos D. Contributions of lifestyle, education, and cardiovascular risk factors to the brain age gap. Aging Brain. 2025;8:100149. doi:10.1016/j.nbas.2025.100149.
- Kapogiannis D, Manolopoulos A, Mullins R, Avgerinos K, Delgado-Peraza F, Mustapic M, Nogueras-Ortiz C, Yao PJ, Pucha KA, Brooks J, Chen Q, Haas SS, Ge R, Hartnell LM, Cookson MR, Egan JM, Frangou S, Mattson MP. Brain responses to intermittent fasting and the healthy living diet in older adults. Cell Metabolism. 2024;36(8):1668–1678.e5. doi:10.1016/j.cmet.2024.05.017.
