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BrainMD Stress Relief Sleep Supplement benefits - promotes healthy stress response, improves sleep quality, lowers cortisol
BrainMD Stress Relief Sleep Supplement comparison to alternative brands.
BrainMD Stress Relief Sleep Supplement backed by clinical studies and designed by brain experts
BrainMD Stress Relief Sleep Supplement customer testimonial
BrainMD Stress Relief Sleep Supplement main ingredients and how they help you sleep better
BrainMD Stress Relief Sleep Supplement - Infographic on how Stress Relief Sleep Supplement helps you sleep better
BrainMD Stress Relief Sleep Supplement - Supplement Facts Panel
New ArrivalMelatonin Free

Stress Relief Sleep

Stress Relief Sleep

Fast-acting, melatonin-free formula designed to lower cortisol for better sleep*

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One-time purchase

Description

Can't turn your brain off at night or too stressed to sleep?

Stress Relief Sleep is a fast-acting, melatonin-free formula that helps your brain and body fully relax so you can fall asleep, stay asleep, and wake up feeling like yourself again.*

No hormones. No grogginess. No habit-forming ingredients, just calm, restorative sleep.*

In clinical studies of KSM-66® Ashwagandha, the cutting-edge adaptogen in Stress Relief Sleep, cortisol levels dropped by up to 28% and 77% of participants reported feeling less anxiousness in just 60 days.*

In a separate study, 49% of participants with severe sleep issues reported significant improvements in sleep quality after only 10 weeks!*

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Key Benefits

Relaxation

Sleep

Stress Support

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.
BrainMD Stress Relief Sleep: infographic supplement facts box
Gluten Free
Vegan
Nut Free
Soy Free
Gluten Free
Vegan
Nut Free
Soy Free

Magnesium

150 mg
Magnesium is a vital mineral needed by every cell in the body, especially for the brain’s nerve cells to communicate effectively.* It supports the electrical signals that allow neurons to connect and process information.* Often called “the relaxation mineral,” magnesium helps regulate muscle tension, hydration, and energy production.* It also balances stress hormones like adrenaline and helps improve sleep quality.* By promoting calmness and mental focus, magnesium plays a key role in supporting emotional well-being, cognitive function, and overall physical health.*

KSM-66® Ashwagandha Root Extract

600 mg
Ashwagandha (Withania somnifera), especially in its clinically studied KSM-66®️ form, is a powerful adaptogenic herb used for centuries in Ayurvedic and traditional medicine.* It helps the body adapt to physical and mental stress by supporting balanced cortisol levels, promoting calm, and enhancing focus.* Research shows that ashwagandha may improve memory, attention, and mental clarity, while also reducing occasional anxiousness and supporting restful sleep.* Its wide-ranging benefits make it a natural choice for promoting emotional resilience, cognitive performance, and overall well-being.*

L-Theanine

300 mg
L-theanine is a calming amino acid naturally found in green tea and widely studied for its stress-reducing effects.* It promotes the production of alpha brain waves, which are linked to a relaxed but alert mental state.* L-theanine helps ease tension and supports a sense of calm without causing drowsiness.* It also contributes to healthy blood pressure regulation, especially during times of stress.* Ideal for promoting focus and emotional balance, l-theanine is a natural way to stay calm, clear-headed, and resilient throughout the day.*

GABA

300 mg
Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the brain’s primary calming neurotransmitter.* It works by inhibiting excessive neural activity, helping to regulate stress responses and promote mental relaxation.* By supporting the brain’s “off switch,” GABA helps quiet racing or anxious thoughts, allowing the mind to settle.* This can lead to improved focus, a more balanced mood, and better sleep quality, making GABA an important nutrient for emotional well-being and overall mental calm.*
BrainMD Stress Relief Sleep: root and leaf sources for powder and capsule supplements

Supported by Clinical Research

Magnesium Supplementation May Support
Stress Relief and Overall Wellbeing

Review and clinical studies on stress, mood, and health benefits

Magnesium plays a role in regulating the stress response, promoting relaxation, and supporting cardiovascular and metabolic health.

(Bekstrand 2011)

(Boyle 2017)

(Al-Alawi 2018)
BrainMD Stress Relief Sleep: woman opening a bottle of supplements
Calm Your Mind, Rest Your Brain

Finally, Fall Asleep & Stay Asleep

Stress doesn’t stop when your head hits the pillow and when it hijacks your sleep, your brain pays the price.* High cortisol doesn’t just delay sleep, it disrupts memory, focus, mood, and recovery.* And poor sleep? It sends cortisol even higher.* That’s why Stress Relief Sleep is designed to reset the cycle -fast.*

With clinically studied ashwagandha, magnesium, GABA, and l-theanine, this brain-targeted sleep supplement helps you calm down, fall asleep, and stay asleep, naturally.*

✔ Fall asleep faster*

✔ Stay asleep longer*

✔ Wake up feeling clear, not cloudy*

Expert Reviews

“Stress and poor sleep are two of the biggest threats to brain health. Stress Relief Sleep is designed to calm the brain, lower cortisol, and help you get the restorative sleep your brain needs to perform at its best.”

Dr. Daniel Amen

Founder, BrainMD & Amen Clinics
"Many of my patients can’t sleep because their stress hormones are too high at night. Stress Relief Sleep addresses this directly by lowering cortisol naturally, without melatonin,so you can relax, fall asleep faster, and wake up feeling refreshed."

Dr. Shane Creado, MD

Board-Certified Sleep Specialist & Psychiatrist, Amen Clinics
"I recommend Stress Relief Sleep to patients who want better sleep without the grogginess of traditional sleep aids. By targeting the stress response, it not only improves sleep but also supports emotional well-being."

Dr. Robert Seawell, PhD

Clinical Psychologist, Amen Clinics
"This formula is unique because it combines clinically studied ashwagandha with magnesium, GABA, and L-theanine nutrients I often recommend separately for relaxation and sleep quality. Together, they provide a comprehensive, non-habit-forming way to reset your stress and sleep cycle."

Zana Dobroshi

MD, PhD, FABA
"When cortisol stays elevated at night, it disrupts deep sleep cycles and impairs brain repair. Stress Relief Sleep’s evidence-based ingredients help quiet the mind and promote the kind of restorative sleep essential for long-term cognitive health."

Dr. Sonia Gera

Adolescent & Adult Psychiatry
BrainMD Stress Relief Sleep: close-up image of capsules with white powder against a blue background
Lower Nighttime Cortisol

Stop The Stress-Sleep Cycle - Fast

Tired but wired? That’s cortisol, your body’s primary stress hormone, flooding your system and keeping your brain stuck in high alert mode.* When cortisol stays elevated at night, it:

✔ Delays sleep onset*

✔ Disrupts deep sleep cycles*

✔ Increases feelings of anxiousness and next-day exhaustion*

Stress Relief Sleep is clinically formulated to reset that cycle - fast.*
BrainMD Stress Relief Sleep: woman stretching after a night of restful sleep

What To Expect

30–60 - Minutes Calming Onset

Calming Onset
Ingredients like L-theanine and magnesium start working quickly to relax the nervous system. Many feel their mind slowing down, tension easing, and an easier transition into sleep the very first night.*
Week 1 - Deeper, Less Restless Sleep

Adaptogens like Relora® and holy basil begin to regulate cortisol, helping you fall asleep more smoothly and stay asleep without frequent wakeups. Nights feel more restorative and mornings less groggy.*
Week 2–4 - Stress + Sleep Synergy

Consistent use compounds benefits: calmer evenings, better mood during the day, and more natural sleep rhythms at night. Many notice less stress reactivity overall, which carries into more restful nights.*
2–3 Months - Long-Term Balance

With continued use, Stress Relief Sleep helps maintain healthier cortisol patterns, deeper restorative sleep, and greater resilience to everyday stress. Over time, this means more energy, better focus, and improved emotional balance throughout the day.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

BrainMD Stress Relief Sleep: supplement bottle against a light yellow background

How do I take Stress Relief Sleep?

Take 2 capsules with water 1–2 hours before your desired bedtime. If you’re still feeling alert after an hour, you may take an additional capsule as needed.* This formula is not recommended for children, or for use during pregnancy or breastfeeding.* Always follow label directions or consult your healthcare provider before use.*

Overall rating: 4.7674417 / 5 from 43 reviews.

AI Generated Review Summary

Stress Relief Sleep is a melatonin-free formula that helps users relax and achieve restorative sleep. Clinical studies show significant improvements in sleep quality and reduced anxiety, with no hormones or grogginess.

Summary topics

  • Sleep Improvement (8%): Customers loved how the supplements significantly improved their sleep, as well as improved their mood.
  • Sleep Quality (48%): Many customers brought up that this sleep aid improved their sleep significantly and provided a better night's sleep.

Review topics: ["improvement","quality","feel","works","difference","sleep","supplement","grogginess"].

Review highlights

  • "The Stress Relief Sleep has improved my sleep significantly and comfortably." — Cynthia
  • "His mood has improved tremendously, which has also made a big difference in our relationship." — Tai
  • "Since starting these supplements, his sleep has improved dramatically." — Tai

Reviews

Works Well!

"This product works well for me. Sometimes I have a hard time falling asleep and take one of the "Put Me to Sleep" tablets. Most of the time I don't need those. I feel the Stress Relief Sleep supplement has helped my overall sleep quality, and I have had sleep issues for years, so I highly recommend them!"

— SANDRA M. (5/5)

Love this one

"I have had sleep issues for around 30 years and have gone through hundreds of supplements, listening to music, trying different foods, or different breathing methods, or different sleeping beds, pillows etc. Somethings would work good for a while, others might work occasionally but not consistently but nothing has worked as well or as consistently as Stress Relief Sleep. I’ve been getting my best sleep with this product. If I wake up at night I will 9 out of 10 times fall right back to sleep. This stuff works! I’ve been using it for several months and I pray it continues to work as well as it has been."

— Deborah G. (5/5)

It didn't work as well

"It didn't work as well as Put Me To Sleep Naturally. I also had strange dreams on the nights that I took this supplement."

— Carrie B. (5/5)

Finally, better sleep!

"Really helps me sleep. . . noticed a big difference the first night."

— Maria M. (5/5)

I think this is the

"I think this is the formula that is good to have a good rest at night . After trying many this is the one"

— Maria B. (5/5)

Stress Relief sleep is a winner for me

"This one is by far my favorite. PUta me to sleep and keeps me asleep. No hang over in the morning. That’s a win!"

— Nicole N. (5/5)

Sleeping well

"These tablets are amazing. I have been able to easily relax and have a better sleep"

— Austin M. (5/5)

Restful and easy sleep

"The Stress Relief Sleep has improved my sleep significantly and comfortably."

— Cynthia (5/5)

Another Happy Customer--Good Sleep FINALLY!

"I purchased this sleep aid for a co-worker who I know has been struggling with trying to get good sleep for the ten years I have known him. He started seeing a difference in his sleep quality right away, and the ashwagandha hasn't even kicked in fully. I got this supplement for my 86 year-old mother and she now sleeps well. She occasionally takes the Put Me to Sleep supplement if she has a hard time falling asleep. I am so happy that this supplement works well for them!"

— Ronda (5/5)

Used to wake up too early

"I usually fall asleep quickly but would wake up after 5 or 6 hours feeling wide awake. I never got very much deep or REM sleep. Since taking this product, I average 7 hours per night and have more deep and REM sleep. I’m even remembering my dreams, which I haven’t done in a long time. I feel a little groggy upon awakening, but it doesn’t last long. It’s better than waking up feeling wired as I did before. This has really helped me."

— Nancy B. (5/5)

Q&A