Red supplement bottle with capsules at the base against a peach-colored background.

BrainMD Advanced Blood Flow: infographic, image of supplement bottle next to brief phrases highlighting benefits

BrainMD Advanced Blood Flow: man holding supplement bottle with green background

BrainMD Advanced Blood Flow: infographic, images and descriptions of the product's 4 main ingredients

BrainMD Advanced Blood Flow: person pouring capsules from a supplement bottle into hand with blurred out interior background

Dr. Amen Favorite

Advanced Blood Flow

Promotes healthy nitric oxide levels for better blood flow + circulation*

Subscribe & Save

1 Unit every month

15% Off Save $4.64

$26.31 Each

6 Units every 6 months

25% Off Save $7.73

$23.22 Each

3 Units every 3 months

20% Off Save $6.19

$24.76 Each

One-time purchase

1 Unit one-time delivery

$30.95

Free Shipping on Orders $75+
Subscribe & Save up to 25% + Free Shipping
100% Money Back Guarantee

Description

Sharper focus. Healthier heart. Better circulation.

Advanced Blood Flow supports healthy nitric oxide levels to improve circulation to the brain and body so you can think clearer, move better, and feel your best at every age, starting now.*

Featuring clinically effective doses of L-citrulline, quercetin anhydrous, trans-resveratrol, and ginkgo biloba, this doctor-developed formula helps restore healthy blood flow to support energy, focus, and long-term health from the inside out.*

Benefits

✔ Promotes healthy nitric oxide levels to support blood flow and circulation*

✔ Enhances brain performance, mental clarity, energy, and healthy aging*

✔ Supports healthy blood pressure already in the normal range*

✔ Improves oxygen and nutrient delivery throughout the body*

✔ Supports heart health, sexual function, and gut and liver health*

How to use

USE: Adults ages 18 and older, take 2 capsules daily. For best results, use consistently as part of your everyday routine.*†

EARLY RESULTS: Many users notice increased energy, sharper focus, and improved circulation within the first 1–2 weeks.*†

LONG-TERM BENEFITS: Continued use supports healthy nitric oxide production, brain performance, heart health, and better aging from the inside out.*†

*†Results may vary based on individual health and fitness levels. Consistent use, in conjunction with a healthy lifestyle, is recommended.

DOCTOR’S RECOMMENDATION: Pair with Brain & Memory Power Boost and Omega-3 Power for comprehensive support for circulation, memory, and mental clarity.*

Ingredients

Ginkgo Biloba Extract
L-Citrulline
Quercetin Anhydrous
Trans-Resveratrol

Key Benefits

Circulation

Energy

Vitality

Brain Health

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.

L-Citrulline

800 mg

L-citrulline is a naturally occurring amino acid that supports healthy blood flow and circulation by boosting the body’s production of nitric oxide, a compound that helps relax and widen blood vessels.* It is converted into L-arginine in the body, which plays a key role in heart health, energy production, and exercise performance.* Although our bodies make some L-citrulline, dietary sources are limited, making supplementation a helpful way to maintain optimal levels for cardiovascular support, endurance, and overall vitality.*

Quercetin Anhydrous

200 mg

Quercetin anhydrous is a potent antioxidant and anti-inflammatory plant compound found in foods like apples, onions, and berries.* It supports healthy circulation by boosting nitric oxide (NO) production and helping to prevent its breakdown, which promotes relaxed blood vessels and cardiovascular health.* Quercetin also helps maintain oxidative balance and supports immune response.* Because the body can’t produce quercetin on its own and natural food sources offer limited absorption—supplementing with a highly bioavailable form can help you gain its full benefits more effectively.*

Ginkgo Biloba Extract

120 mg

Ginkgo biloba extract, derived from the leaves of the ginkgo tree, is one of the most studied herbal supplements for cognitive health.* It supports healthy circulation, especially to the brain, which is essential for memory, focus, and mental clarity.* Ginkgo is rich in antioxidants that help protect brain cells from oxidative stress and age-related damage.* Clinical research suggests it may enhance mental sharpness and support overall brain function, particularly in aging populations.*

Trans-Resveratrol

30 mg

Trans-resveratrol is the highly bioavailable and active form of resveratrol, a powerful antioxidant polyphenol found in plants like grapes and berries.* It supports cardiovascular health by boosting nitric oxide levels, which improve blood flow and vessel function.* Trans-resveratrol also helps protect cells from oxidative stress, promotes a healthy inflammatory response, and supports healthy aging.* Compared to its less active form (cis-resveratrol), trans-resveratrol is more easily absorbed and utilized by the body, making it especially effective for overall wellness and cellular protection.*

Supported by Clinical Research

Grape Seed Supports Cardiovascular Wellness

Clinical study in adults with high blood pressure

Research suggests grape seed extract helps support healthy circulation and cardiovascular function.

(Feringa 2011)

Hawthorn Supports Heart Performance

Meta-analysis of randomized trials

A review of clinical studies found hawthorn extract supports heart performance and overall cardiovascular health.

(Pittler 2003)

Ginkgo Helps Support Brain Circulation

Clinical studies on mental performance

Research on ginkgo biloba shows benefits for supporting brain circulation and healthy cognitive function.

(Kleijnen 1992)

L-Citrulline Supports Circulation

Clinical study on nitric oxide metabolism

Human studies demonstrate L-citrulline helps the body generate nitric oxide, supporting healthy blood flow and vascular function.

(Schwedhelm 2008)

Blood Flow Declines With Age

But Your Energy Doesn’t Have To

By your 40s, your body produces about 50% less nitric oxide than it did when you were younger. This matters—because nitric oxide plays a crucial role in expanding blood vessels and keeping circulation strong. Less nitric oxide means reduced blood flow, which can show up as brain fog, fatigue, poor exercise recovery, and even issues with heart, gut, and sexual health.*

Advanced Blood Flow helps you take control. With clinically studied nutrients that promote natural nitric oxide production, this groundbreaking formula supports the healthy circulation your brain and body need to stay sharp, energized, and resilient as you age.*

“Blood flow is essential for brain function and most people don’t realize it declines with age. That’s why I formulated Advanced Blood Flow. It’s packed with ingredients that support nitric oxide production, circulation, and memory so you can protect your brain and body every day.”

“Advanced Blood Flow combines clinically researched nutrients to support nitric oxide production and healthy circulation. This formula can help enhance energy, focus, and cardiovascular health key factors in healthy aging and brain performance.”

“As a nurse and nutritionist, I’m always looking for targeted, science-backed support for circulation and energy. I love that Advanced Blood Flow supports the entire system—especially brain and heart health—with clean, effective ingredients.”

“Cognitive fog, low energy, even mood swings many of these symptoms can be tied to poor circulation. Advanced Blood Flow delivers key nutrients to help improve blood flow and support brain function.”

“Nitric oxide plays a critical role in whole-body health from immune resilience to vascular function. Advanced Blood Flow is a smart way to support this system naturally, especially as nitric oxide production declines with age.”

Doctor-Developed

For Better Brain + Body Circulation

Dr. Daniel Amen designed this formula with one goal: to restore healthy blood flow throughout the brain and body. It features L-citrulline to support nitric oxide production, quercetin anhydrous and trans-resveratrol for circulation and antioxidant defense, and ginkgo biloba for memory and mental clarity.*

This is more than just a nitric oxide supplement, it's your daily circulation support system, helping you feel clearer, stronger, and more vibrant every single day.*

What To Expect

Day 1 – Circulation Support Begins

L-citrulline starts converting to nitric oxide, supporting healthy blood flow and oxygen delivery throughout your body and brain.*

Week 2 – Energy & Endurance

Studies show citrulline and quercetin may support stamina, exercise performance, and cellular energy within the first couple of weeks helping you feel more alert and resilient.*

Week 4 – Sharper Thinking & Focus

By week 4, ingredients like ginkgo and resveratrol begin supporting healthy circulation to the brain, which research links to improvements in memory, focus, and mental clarity.*

Week 12 – Long-Term Vascular & Cognitive Benefits

With consistent use, the synergistic blend of L-citrulline, quercetin, resveratrol, and ginkgo helps sustain healthy blood vessel function, protect brain cells from oxidative stress, and support long-term cognitive performance.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

How do I take Advanced Blood Flow?

It’s recommended for adults, ages 18 and older, to take 2 capsules daily.*

Why does this supplement contain antioxidants?

Studies have found that the antioxidants in this formula are especially important in nitric oxide production and metabolism, especially when compared to the antioxidant components found in foods.*

Can this supplement make me dependent on it?

No. This dietary supplement isn’t a drug and isn’t habit-forming.*

Is this product safe to take during pregnancy?

Due to insufficient scientific safety data, we don’t recommend taking Advanced Blood Flow while pregnant or breastfeeding.*

Does this product have any cautions?

Taking quercetin and blood thinners (like Warfarin) together might increase the effects and side effects of blood thinners, which could increase the risk of bruising and bleeding.*

Overall rating: 4.688679 / 5 from 212 reviews.

AI Generated Review Summary

Advanced Blood Flow supports healthy nitric oxide levels to improve circulation, enhancing focus and energy. Customers appreciate the significant difference it makes in their well-being and overall energy levels. The supplement is highly valued for its effectiveness and quality, though some did not notice changes in blood pressure.

Summary topics

Well-being Improvement (7%): Customers appreciated the significant difference it made in their well-being and overall energy levels for them.
Blood Flow Improvement (10%): It was observed by customers that the advanced blood flow provided by the product greatly improved their focus and outlook.
Positive Results (7%): Customers loved the amazing and positive results they achieved with the product, with some even planning to continue using it.
Feeling Great (5%): Customers keep praising how great and alive they feel after using the product for just a month.
Supplement Value (7%): Customers appreciated the supplement, as it helps them think more clearly and is a good value for the money.

Review topics: ["feel","results","quality","blood flow","improvement","energy","pain","supplement","ingredients","impact","difference","blood pressure","brain","effect","works","circulation","periods of time","help","increase","focus","life","term","mind","relaxation","memory","addition","information","legs","capsules","order"].

Review highlights

"I love the Advanced Blood Flow and the difference it has made in focus and outlook and energy for me." — Lois H.
"I always trust that I am getting the highest quality ingredients and products from Dr. Amen and Brain MD." — Charles L.
"My sinuses open up being able to breathe better after taking blood flow." — Leola J.

Reviews

Life’s body language

"Nothing is more important to your mind, heart and body than a healthy circulatory system. It’s literally the flow of life and energy. So when you’re looking for the purest form of quality support for every part of your body, naturally BrainMD was my favorite choice. I’m supplementing my diet with their products daily and this one is a perfect fit to complement their other ones. Safe, pure, and effective."

— Peter R. (5/5)

Has made a difference for both my daughters

"For my daughter (18) that has ADHD and Ehler's Danlos Syndrome and would pass out at school this has been a game changer. She does not pass out ever any more and feels great. Her BP would drop when getting up, no longer does that happen. She has been taking this going on 3 years. My other daughter (20) takes this and just feels that much better she too has ADHD."

— Kristin M. (5/5)

Grateful

"OMG had a TBI, began supplements doctor Cone, prescribed me. I couldn’t take them for 5 days before a surgery. All of the terrible symptoms returned. So once I got back on the supplements, I knew they worked & I needed them. Grateful for scientists."

— Sally F. (5/5)

As a survivor of a

"As a survivor of a ruptured brain aneurysm I wanted something that I felt confident in and believed it would help with blood flow in my brain and arteries. I’m feeling confident with this product and will continue purchasing it in the future."

— Jennifer Z. (5/5)

Great product!

"I recently started using Advanced Blood Flow. While I'm just a few weeks in, it appears to be helping with mental sharpness and my blood pressure is a little lower!"

— TONY M. (5/5)

Advanced Blood Flow capsules

"BrainMD's Advanced Blood Flow capsules is very effective in gently providing circulation support and enhancing my energy, memory and ability to concentrate for longer periods of time. I take it daily with breakfast and highly recommend it!"

— yuko n. (5/5)

Better Blood Pressure

"I'm noticed my blood pressure remains stable after taking for 30 days. It is working for me."

— Austin T. (5/5)

Excellent Product!

"Excellent product! I have been using Advanced blood flow for nearly 2 years and I love that it gives me energy in the afternoon when I typically get that 2 pm slump. It makes me feel more alert, energized, focused, and able to finish my work for the day. I highly recommend this product to anyone. Thanks!"

— Darla H. (5/5)

helps me with my heart rate

"Thank you for your products which support me, with trust, I heard you decades ago when I was studying the brain, and never realized then how much when I was 82 that this would be meaningful!"

— Joan H. (5/5)

Very Good

"This supplement helps me to keep my blood pressure in the normal range. I have diabetes and I believe this supplement helps with circulation to my feet. I don’t have the nerve pain that I used to."

— Sandra D. (5/5)

Build Your Own Bundle

The Science Behind Brain Types

Not Sure Which Brain Type You Are?

Find Your Brain Type

What’s Your Stress Type?

Wake Up Feeling Refreshed

Build Your Own Bundle

Not Sure Which Brain Type You Are?

Advanced Blood Flow