1 large orange supplement bottle and 2 small purple supplement bottles against a yellow background.

Infographic - various bottles and capsules above the benefits of a Sleep Trio.

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3 different supplement bottles with diffuser, essential oils and feathers against a lavender background.

Supplement Facts box listing the ingredients in GABA Calming Support.

Supplement Facts box listing the ingredient in Magnesium Chewables.

Supplement Facts box listing the ingredients in Restful Sleep.

Better Sleep Protocol

Name: Better Sleep Protocol
Brand: BrainMD by Daniel Amen, MD
SKU: 1561
Price: 91.95 USD
Availability: InStock
Rating: 4.4 (14 reviews)

Tana Amen’s nightly “sleep cocktail” for deep, restorative rest*

$91.95

Shipping calculated at checkout.

Includes:

GABA Calming Support
Magnesium Chewables
Restful Sleep

Description

Sleep is the foundation of brain health, emotional balance, and overall vitality—but for many, it’s elusive. That’s why Tana Amen, BSN, RN, created her personal bedtime protocol: a simple 3-in-1 system designed to help you relax, fall asleep faster, and stay asleep longer.*

This protocol combines:

GABA Calming Support — Promotes relaxation and eases mental tension so your mind is ready for rest.*

Magnesium Chewables — Supports muscle relaxation, calm nerves, and helps regulate healthy sleep patterns.*

Restful Sleep — A gentle, non-habit-forming blend to support falling asleep and waking refreshed.*

Trusted by Tana Amen and used nightly, this synergistic trio helps prepare your body and brain for deep, restorative sleep.*

How to use

GABA Calming Support: Adults take 1 to 6 capsules daily with water, on an empty stomach, or as directed by your healthcare provider.*

Magnesium Chewables: Take 2 chewables before bed. Chew thoroughly before swallowing.*

Restful Sleep: Take 1–4 capsules of Restful Sleep 30–60 minutes before bedtime, or as directed by your healthcare professional.*

*Results may vary based on individual health and fitness levels. Consistent use, in conjunction with a healthy lifestyle, is recommended.

Ingredients

GABA Calming Support

GABA
Lemon Balm Extract
L-Theanine

Magnesium

Vitamin B6
Magnesium Chewables
Magnesium

Restful Sleep

GABA
Magnesium
Melatonin
Valerian Extract
Vitamin B6

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Key Benefits

Sleep

Calm

Relaxation

GABA Calming Support Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.

Vitamin B6

8 mg

Vitamin B6, as pyridoxine and pyridoxal-5-phosphate, is essential for at least 100 enzymes that help the brain make key neurotransmitters. It helps the body utilize carbohydrates, fats and amino acids derived from proteins. Vitamin B6 aids the conversion of potentially damaging homocysteine into useful antioxidants. It also promotes relaxation and healthy mood. This formula provides the two chemical forms of B6 that are most fully absorbed and utilized.

Magnesium

33 mg

Magnesium is a vital mineral needed by every cell in the body, especially for the brain’s nerve cells to communicate effectively.* It supports the electrical signals that allow neurons to connect and process information.* Often called “the relaxation mineral,” magnesium helps regulate muscle tension, hydration, and energy production.* It also balances stress hormones like adrenaline and helps improve sleep quality.* By promoting calmness and mental focus, magnesium plays a key role in supporting emotional well-being, cognitive function, and overall physical health.*

Lemon Balm Extract

50 mg

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GABA

250 mg

Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the brain’s primary calming neurotransmitter.* It works by slowing down excessive neural activity, helping to reduce feelings of anxiousness, tension, and overstimulation.* By activating the brain’s “off switch,” GABA supports a relaxed mental state, eases racing thoughts, and promotes emotional balance.* This calming effect can enhance focus, improve sleep quality, and support the body’s natural stress response for overall mental well-being.*

L-Theanine

33 mg

L-theanine is a calming amino acid naturally found in green tea and widely studied for its stress-reducing effects.* It promotes the production of alpha brain waves, which are linked to a relaxed but alert mental state.* L-theanine helps ease tension and supports a sense of calm without causing drowsiness.* It also contributes to healthy blood pressure regulation, especially during times of stress.* Ideal for promoting focus and emotional balance, l-theanine is a natural way to stay calm, clear-headed, and resilient throughout the day.*

Magnesium Chewables Key Ingredients

Magnesium

150 mg

Restful Sleep Key Ingredients

GABA

375 mg

Magnesium

50 mg

Vitamin B6

10 mg

Vitamin B6, provided as both pyridoxine and its active form pyridoxal-5-phosphate, is essential for brain and metabolic health.* It supports over 100 enzyme reactions involved in producing neurotransmitters like serotonin and dopamine, which help regulate mood, focus, and relaxation.* B6 also plays a key role in metabolizing carbohydrates, fats, and proteins for energy, and helps convert homocysteine—a potentially harmful compound—into beneficial antioxidants.* This dual-form formula ensures optimal absorption and effectiveness for nervous system support and overall well-being.*

Valerian Extract

300 mg

Valerian root is a traditional herb long used to promote relaxation and better sleep.* It is believed to work by interacting with GABA receptors in the brain—key pathways that help calm nervous system activity and ease mental tension.* By supporting the body’s natural calming mechanisms, valerian helps reduce the time it takes to fall asleep and encourages deeper, more restorative rest.* It’s especially useful for promoting sleep quality without the grogginess often associated with sleep aids.*

Melatonin

2.5 mg

Melatonin is a naturally occurring hormone produced by the brain in response to darkness, helping regulate your internal sleep-wake cycle.* It signals to the body that it’s time to wind down, supporting the natural transition to sleep.* Factors like aging, travel across time zones, and certain medications can reduce melatonin levels, disrupting sleep patterns.* Supplementing with melatonin can help restore healthy circadian rhythms, promote faster sleep onset, and improve overall sleep quality—supporting more restful and consistent sleep.*

BrainMD Better Sleep Bundle: glass containers with capsules, tablets, powder, green leaves and orange slice on white surface

Supported by Clinical Research

GABA Supplementation May Reduce Stress and Improve Sleep

Randomized controlled trial on oral GABA administration

Oral gamma-aminobutyric acid (GABA) supplementation was found to support relaxation, reduce stress, and improve sleep quality in healthy adults.

(Hepsomali 2020)

GABA Plays a Key Role in Sleep Regulation

Mechanistic review of GABA in sleep physiology

This review outlines how GABAergic pathways modulate sleep stages, providing a mechanistic basis for using GABA-related supplements to support healthy sleep patterns.

(Gottesmann 2002)

Valerian Root May Improve Sleep Quality

Systematic review and meta-analysis of clinical studies

Evidence shows valerian supplementation may reduce sleep latency and improve overall sleep quality in adults with insomnia and other sleep disturbances.

(Bent 2015)

Vitamin B6 May Help Mitigate Effects of Sleep Deprivation

Preclinical evidence on B6 supplementation

Vitamin B6 supplementation was shown to alleviate the negative effects of chronic sleep deprivation on cognition and mood.

(Yuan 2024)

Magnesium Supplementation May Help Reduce Anxiety and Stress

Double-blind, placebo-controlled study in healthy adults

This study demonstrated that magnesium supplementation led to reductions in subjective measures of stress and anxiety in individuals with low baseline magnesium levels.

(Boyle 2017)

BrainMD Better Sleep Bundle: man and woman having a conversation, interior bedroom setting

Tana’s Bedtime Formula*

Your New Nightly Reset*

This isn’t just any sleep bundle—it’s Tana Amen’s personal bedtime “cocktail.” Designed to address the root causes of sleeplessness, this protocol helps calm your mind, relax your muscles, and ease you into restorative rest.* Whether you struggle to unwind, wake frequently in the night, or want to protect your long-term brain health, this simple nightly ritual can help you get the quality sleep you’ve been missing.*

“This sleep combo is literally my bedtime ‘cocktail.’ As someone with thyroid problems, I often have trouble sleeping—but this knocks me out for a solid night of rest.”

BrainMD Better Sleep Bundle: 3 supplement bottles of different sizes and colors on a nightstand in a bedroom

Fall Asleep Faster, Stay Asleep Longer*

With targeted nutrients for your brain, nervous system, and muscles, the Better Sleep Bundle works synergistically to prepare every part of you for rest.* GABA Calming Support soothes a racing mind, Magnesium Chewables relax the body, and Restful Sleep supports your natural sleep cycle.* Together, they help you fall asleep faster, stay asleep longer, and wake up feeling like yourself again.*

BrainMD Better Sleep Bundle: smiling man wrapped in a blue blanket, blurred bedroom background

What To Expect

Night 1 – Wind Down Easier

Feel a greater sense of calm and relaxation as you prepare for bed.*

Week 1 – Fall Asleep Faster

Begin noticing less tossing, turning, and mental chatter at bedtime.*

Week 3 – Sleep More Soundly

Experience fewer nighttime wakeups and deeper, more restorative rest.*

Month 2 & Beyond – Long-Term Sleep Support

Consistent, high-quality sleep supports sharper thinking, better mood, and all-day energy.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

BrainMD Better Sleep Bundle: smiling man pouring supplements into his hand, interior bedroom setting

Does this product help with sleep?

Yes, GABA Calming Support enhances calm and helps you unwind at the end of the day, which may lead to quality sleep.*

Will GABA Calming Support make me groggy during the day?

No. GABA Calming Support is designed to help calm an overactive mind and promote relaxation in the body.* It does not cause grogginess.*

Does this supplement promote relaxation?

Known as “the relaxation mineral,” magnesium can help keep you emotionally balanced and mentally sharp while you’re awake…and help you relax and recharge at night.* This product generates charged magnesium atoms far better than many lower-quality products.*

Does this product contain melatonin?

Yes. Melatonin is a hormone that prepares your body for sleep.* Unfortunately, melatonin production declines with age and is disrupted by nutrient deficiencies, shift work, and blue light exposure at night.* Those with attention challenges can also experience delays in melatonin release, pushing bedtime later than desired.* Restful Sleep provides a powerful dose of 2.5 mg of melatonin per serving to help you fall asleep and stay asleep so you can wake up feeling refreshed.*

Are there long-term benefits to using this supplement?

Yes! Consistent nightly use may help reset your circadian rhythm and support deeper, more restorative sleep over time.*

Overall rating: 4.4666667 / 5 from 15 reviews.

AI Generated Review Summary

Summary topics

Review topics: [sleep, stay, difference].

Review highlights

Reviews

Better Sleep

"The combination of the Better Sleep Protocol, really was helpful a few different times throughout my day. The Gaba calming support is very useful during the day, the Magnesium Chewables are a good afternoon and eveningsupplement & Restful Sleep is perfect for the night sleep."

— Brent S. (5/5)

review

"This came in a timely manner and will hopefully provide my sweetheart with deep REM sleep."

— Corbett A. (5/5)

I noticed a significant difference

"I noticed a significant difference in waking during the night and was able to stay asleep for 7 hours."

— Leigh M. (5/5)

Those work pills work great.

"Those work pills work great. I can't stress that enough."

— Jermaine W. (5/5)

My go-tos for sleep

"This combo has made a huge difference in my sleep and done know what I’d do without them Love all of Dr. Amen’s supplements!!"

— Samantha E. (5/5)

Giving it more time

"I have only been using for about a month. Honestly, I don't really know what to expect. I do fall asleep but I don't stay asleep. I am gonna give it a few more weeks."

— Denise P. (3/5)

These are recommended to me

"These are recommended to me from my physician, already feeling and sleeping better!"

— Cindy S. (5/5)

GABA great Magnesium okay Restful

"GABA great Magnesium okay Restful Sleep terrible —"

— Gloria S. (5/5)

I use the rest full

"I use the rest full sleep every night, along with the Gaba caps every so often, when I need calmness due to overactive thoughts. I only have used the magnesium tabs a few times, when I have leg or foot cramps."

— Sherry T. (4/5)

I just started a week

"I just started a week ago , I need some time to see if it works , thanks"

— Rafael A. (3/5)

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