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"I need to supplement with methylfolate and this is a quality product! Got my labs back where they need to be."
MethylFolate
MethylFolate
Highly bioavailable MethylFolate
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Description
Description
If you have the MTHFR gene variant, your body may struggle to convert folic acid into its active form. That's where MethylFolate comes in. This doctor-developed formula delivers the bioactive form of folate your brain and body can actually use, supporting healthy methylation, balanced mood, clear memory, heart and immune health, and more.*
Unlike folic acid, MethylFolate crosses the blood-brain barrier for fast, effective results, especially important for those with MTHFR gene variants or elevated homocysteine levels.*
Benefits
Benefits
How to use
How to use
Ingredients
Ingredients
Key Benefits
Mood
Key Ingredients
Folate
5000 mcg
This formula provides folate in its most active form, methylfolate (MTHF), which the body can use immediately—especially important for those with difficulty converting synthetic folic acid.* MTHF supports the brain’s production of neurotransmitters like serotonin and dopamine, helps generate melatonin for healthy sleep, and is essential for forming myelin, the protective coating around nerve cells.* It also aids in processing homocysteine, a metabolic byproduct that can be harmful at high levels.* Methylfolate supports mood, cognitive function, and overall neurological and cardiovascular health.*
Folate
This formula provides folate in its most active form, methylfolate (MTHF), which the body can use immediately—especially important for those with difficulty converting synthetic folic acid.* MTHF supports the brain’s production of neurotransmitters like serotonin and dopamine, helps generate melatonin for healthy sleep, and is essential for forming myelin, the protective coating around nerve cells.* It also aids in processing homocysteine, a metabolic byproduct that can be harmful at high levels.* Methylfolate supports mood, cognitive function, and overall neurological and cardiovascular health.*
The BrainMD Difference
Formulated by leading brain health experts, this blend uses ingredients shown in human studies to support serotonin levels, reduce emotional eating, and ease everyday stress—without side effects or habit-forming ingredients.*
Peer-Reviewed Scientific Studies
Young, S.N. (2007) Folate and depression—a neglected problem
https://pmc.ncbi.nlm.nih.gov/articles/PMC1810582/
7x More Bioavailable Than Synthetic Folic Acid*
Expert Reviews
“With MethylFolate, you can support a wide array of critical brain functions, including mood support, across your entire lifespan.”
Dr. Daniel Amen
Founder, BrainMD & Amen Clinics
"BrainMD Methylfolate contains folate in its most active, bioavailable form. Supportive for mood, brain health, heart health, pregnancy, and ideal for those with methylation mutations, such as MTHFR."
Dr. Julie Brush
Naturopathic Doctor
Powerful Support For Brain, Mood & More*
What To Expect
Week 1 - Bioavailable Boost
Week 2 - Better Mood & Mental Clarity
Week 4 - Cardiovascular & Brain Benefits
Week 12+ - Long-Term Resilience
FAQ
It’s recommended that adults take 1 capsule of MethylFolate daily with food, which supplies 5 mg of methylfolate.* When under the guidance of a nutritionally-informed physician, you can take up to 3 capsules (15 mg) per day.*
It’s recommended that adults take 1 capsule of MethylFolate daily with food, which supplies 5 mg of methylfolate.* When under the guidance of a nutritionally-informed physician, you can take up to 3 capsules (15 mg) per day.*
Is this supplement safe to take?
Is this supplement safe to take?
Can I use this supplement if I’m currently taking methotrexate?
Can I use this supplement if I’m currently taking methotrexate?
Is this product compatible with other dietary supplements?
Is this product compatible with other dietary supplements?
Overall rating: 4.65625 / 5 from 64 reviews.
AI Generated Review Summary
MethylFolate is a doctor-developed supplement that provides the bioactive form of folate, supporting healthy methylation, balanced mood, clear memory, and heart and immune health. Customers praise its effectiveness and consistency, noting significant improvements in daily functioning and mood.
Summary topics
- Supplement Effectiveness (14%): Customers raved about this supplement, stating that it is amazing and great for mental health challenges.
- Daily Functioning Improvement (22%): Many customers raved about how this product made a huge difference in their daily functioning and mood.
- Product Quality (19%): A significant number of customers remarked on the high quality of the products, praising their effectiveness and consistency.
Review topics: ["quality","results","feel","issues","works","difference","supplement","change","effect","level","headaches","anxiety"].
Review highlights
- "Awesome product - high quality supplement for a grwat orice" —
- "Appreciate high quality products I can trust." —
- "I notice a positive difference in my energy and mood and am happy with the results and quality of this product." —
Reviews
Great product!
"Been taking this for a few years now and have been pleased with the results."
I love this supplement
"Great used it with my prenatal"
Flushing/ blushing
"I’ve appreciated this product so far. I have noticed a little bit of flushing after taking it. Overall, it’s a good product."
Can't tell yet.
"Just started"
Consistent Quality and Effective Brain Support
"My family and I appreciate the consistent quality of the Methylfolate from Brain MD after trying other brands and getting inconsistent results. We know this product supports our brains, helps us combat depression symptoms and feel our best!"