NEW Perimenopause Support+ | Get Your 3rd Month FREE **
BrainMD Smart Creatine+ creatine monohydrate tub with third-party lab tested badge, NSF Certified for Sport
BrainMD Smart Creatine+: blue supplement container and water bottle next to brief phrases highlighting product benefits
BrainMD Smart Creatine+: blue supplement container & water bottle in foreground, blurred woman doing headstand in background
BrainMD Smart Creatine+: blue supplement container and clear glass of water next to competitor's creatine and cloudy water
BrainMD Smart Creatine+: woman dropping a scoop of white powder from a blue supplement container into a blender
BrainMD Smart Creatine+: infographic, supplement facts box
TikTok ViralNSF CertifiedDr. Amen FavoriteBest Seller

Smart Creatine+

Smart Creatine+

Power your brain and body with NSF Certified instantized creatine monohydrate*

Subscribe & Save
One-time purchase
  • Free shipping iconFree Shipping on Orders $75+
  • Subscribe and save iconSubscribe & Save up to 25% + Free Shipping
  • 100% money back guarantee icon100% Money Back Guarantee

Description

Reach your fitness goals faster, enhance cognitive function, build and maintain muscle, and experience the power of instantized creatine monohydrate with Smart Creatine+.* Our advanced, NSF Certified For Sport, no bloat, naturally instantized formula offers 100% soluble and highly bioavailable creatine for improved absorption, drinkability and digestion.*

Formulated with iCreatine®, the cleanest and purest instantized creatine monohydrate on the market, Smart Creatine+ helps fuel your body and brain for peak physical and mental performance.*

Key Benefits

Energy benefit icon

Energy

Performance

Brain Health

Healthy Aging

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.
Soy Free
Sugar Free
Nut Free
Vegan
Gluten Free
Keto Friendly
Soy Free
Sugar Free
Nut Free
Vegan
Gluten Free
Keto Friendly

NutraAssure® iCreatine® Creatine Monohydrate

5g
NutraAssure®️ iCreatine®️ is a premium, patented form of creatine monohydrate engineered for optimal absorption, solubility, and digestion—without the need for additives like soy lecithin.* This “instantized” creatine is micronized during the crystallization process to dissolve easily and avoid bloating or grittiness.* In the body, creatine helps replenish cellular energy (ATP), enhancing physical performance, strength, and endurance.* Emerging research also links creatine to improved cognitive function and overall brain health, making it a valuable supplement for both body and mind.*

Supported by Clinical Research

Creatine Supplementation May Improve Muscle Strength and Mass
Meta-analyses and clinical trials on performance and resistance training

Creatine has been widely studied for its ability to increase lean muscle mass, power output, and strength during resistance training in both young and older adults.
(Kreider 2017)
(Chilibeck 2017)
(Want 2024)
BrainMD
POWER Your Performance With Smart Creatine+*

Benefits Beyond The Gym*

Creatine is a naturally occurring compound that fuels your cells’ primary energy molecule — ATP.* Over time, natural creatine stores decline, impacting muscle strength, endurance, and even cognitive performance.*

Smart Creatine+ restores and maintains optimal levels with high-purity iCreatine® — naturally instantized for maximum solubility and absorption. No gritty texture. No digestive discomfort. Just fast, effective support for your body and brain.*

Expert Reviews

“The brain-specific benefits of instantized creatine are truly remarkable, aiding in cognitive function, memory retention, and overall mental clarity. Smart Creatine+ is perfect for anyone looking to boost the health of both their brain and body.”

Dr. Daniel Amen

Founder, BrainMD & Amen Clinics
BrainMD
Formulated For Everyone

Not Just Athletes*

Creatine has a reputation for sports performance, but research shows it’s also a powerful brain and longevity nutrient.*

✔ Enhances Cognitive Function: Supports memory, focus, and mental clarity while protecting against oxidative stress in the brain.*

✔ Supports Healthy Metabolism: In one study, 5 g/day for 8 weeks reduced cholesterol and triglycerides in adults with high levels.*

✔ Optimizes Women’s Health: Benefits mood, bone strength, and exercise capacity—especially post-menopause.*

✔ Promotes Longevity in Older Adults: Improves muscle strength, reduces fatigue, and supports daily mobility—even without exercise.*

Smart Creatine+ makes it easy to get these proven benefits in a clean, instantly dissolving formula you’ll actually enjoy taking.*
BrainMD

What To Expect

Week 1

Cellular energy starts to rise as creatine replenishes ATP in your brain and muscles. Many feel an immediate lift in stamina and mental sharpness during workouts or mentally demanding tasks.*
Week 2

Strength, power, and recovery improvements begin to show in the gym, while daily use supports clearer focus, faster recall, and reduced mental fatigue.*
Week 4

Consistent use builds creatine stores in the brain and body. Expect noticeable gains in endurance, faster post-exercise recovery, and improved cognitive performance under stress or sleep deprivation.*
8–12 Weeks

Benefits compound: stronger lifts, sustained energy, better muscle retention, and long-term support for memory and cognition. You’ll feel sharper, more resilient, and physically stronger.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

BrainMD

Overall rating: 4.858223 / 5 from 529 reviews.

AI Generated Review Summary

Smart Creatine+ offers a highly bioavailable creatine formula that enhances energy levels, mental clarity, and muscle strength. Customers appreciate its easy mixability, great taste, and effectiveness without bloating. Results show significant improvements in physical and cognitive performance.

Summary topics

  • Energy and Mental Clarity Improvement (9%): It was highlighted by customers that they noticed a significant difference in their energy levels and mental clarity.
  • Energy and Focus (5%): It was highlighted by customers that the product provides great energy and focus in workouts and overall health.
  • Muscle Strength and Energy (5%): Customers appreciated the ability of this product to make them feel stronger and more energetic. (Common opinion)
  • Mixability and Taste (6%): It was observed by customers that this powder is very easy to mix and has a great taste.
  • Creatine Quality (14%): Customers raved about this creatine, calling it one of the best they've ever taken.

Review topics: ["feel","results","energy","issues","quality","muscles","benefits","shipping","improvement","stomach","consistency","felt","texture","body","residue","price","boost","impact","weight","creatine","formula","blend","pain","taste","sugar","strength","container","difference","powder","bloating"].

Review highlights

  • "I've been taking Smart Creatine daily for about a month and notice quicker recovery, better sleep and less foggy brain." — SUSAN M.
  • "I love it, feel powerful, strong, no bloating whatsoever" — Alina L.
  • "I feel the difference right away." — Satoka E.

Reviews

New to Creatine+

"With lots of Creatine on the market going with Dr. Amen’s line was a no brainer. I’m 45 female . After 3 months I gained muscle, dropped in body fat % , and noticed some mental clarity. Praises!!!"

— Kristin D. (5/5)

Clarity in Creatine!

"I’ve been taking Smart Creatine for about a month now, and I’m really happy with the results so far. The biggest difference I’ve noticed has actually been in my focus and mental clarity. I feel more alert, less mentally foggy, and better able to stay on task throughout the day. I originally started taking creatine for the physical benefits, but the cognitive benefits have been such a nice surprise. It’s become an easy addition to my daily routine, and I definitely plan on continuing to use it!"

— Jenna M. (5/5)

awesome

"no flavor. easy to take dissolves fast. Ive only had it for 2 weeks. I feel better, think better, a little more energy. I approve of this stuff. I love Brain MD products. I have the Entergy and focus and the Saffron. Everything I order never works but this line does."

— B***** P. (5/5)

Great for recovery!

"Felt little to no soreness after workouts. Also mixes better than momentous, the only other brand I tried. Momentous is gritty and harder for me to digest. I’ve noticed slight bloating with both."

— Natalie C. (5/5)

BEST Creatine EVER!

"I've used different creatine products through the years & this one is the most superior! On days when I didn't sleep as well, I will do an extra scoop in my water or coffee & it makes me feel normal! Not tired or dragging, just awake and vibrant! I workout everyday and NEVER have muscle soreness. Brain MD Smart Creatine is part of my daily morning coffee routine! I'm SO grateful I found them!"

— Teresa D. (5/5)

Love it!!

"This creatine powder mixes easily in with my smoothies or even plain water with no taste and absolutely no clumps. It’s so easy to incorporate into my daily routine and it’s great knowing that I’m giving my body a health boost."

— Casie S. (5/5)

Creatine Newbie

"I’m still trying out the smart creatine but notice more energy and better focus so far. Hopefully these benefits continue."

— Debbie N. (5/5)

I am learning to play Chess at 71.

"I really seem to have sharper brain function when I take this. If you are learning to play chess for real you know it’s working when you beat the computer. This is definitely working!"

— Maria L. (5/5)

Changed my brain helped to change my mind

"With taking all of the recommended supplements to assist with brain health, this really has benefited me in my entire thought process in my brain is functioning so much better and I’m so much more positive. I recommend taking these brain health supplements."

— Richard A. (5/5)

Doesn’t clump

"I have only been taking it for about a week. I’ll be back to update soon. I do appreciate that it doesn’t have a bad taste and that it dissolves well. I’ve taken it with water, a splash of apple juice, and my shake. No strong flavor noted."

— Diana M. (4/5)

Q&A