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BrainMD Vitamin D3 + K2: raw powders of the two ingredients, brief descriptions against a light blue background
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Vitamin D3 + K2

Vitamin D3 + K2

High potency vitamin D3 + K2*

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Description

This powerful combination of vitamin D3 (as cholecalciferol) and vitamin K2 (as MK-7) helps strengthen bones, promote cardiovascular health, fight oxidative stress, support the immune system, preserve cognitive function and more.*

Key Benefits

Mood

Circulation

Immunity

Key Ingredients

We only use clinically researched ingredients backed by science. Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.
BrainMD Vitamin D3 + K2: infographic supplement facts box
Soy Free
Gluten Free
Sugar Free
Dairy & Egg Free
Soy Free
Gluten Free
Sugar Free
Dairy & Egg Free
Vitamin D3 ingredient

Vitamin D3

125 mcg [5000 IU]
Vitamin D3, often called the “sunshine vitamin,” is essential for overall health and is produced in the skin when exposed to sunlight.* The liver and kidneys convert vitamin D3 into an active hormone that supports bone growth, immune function, brain health, and heart function.* Unlike vitamin D2, D3 is more effective at raising and maintaining vitamin D levels in the body.* It also plays a key role in promoting healthy mood balance and cognitive performance, making it vital for both physical and mental well-being.*
Vitamin K2 ingredient

Vitamin K2

180 mcg
Vitamin K2 is essential for guiding calcium to the right places in the body.* It activates proteins that help direct calcium into bones and teeth—where it strengthens structure—and away from arteries, where buildup can be harmful.* This dual action supports both bone density and cardiovascular health.* Especially important during and after menopause, Vitamin K2 helps maintain strong bones and a healthy heart by keeping calcium in balance.*
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Supported by Clinical Research

Vitamin K2 Supports Bone and Cardiovascular Health

Systematic reviews and clinical research on K2

Vitamin K2 (menaquinone) has been shown to support bone mineralization and inhibit arterial calcification. It's especially relevant in postmenopausal osteoporosis and early-life development.

(Schwalfenberg 2017)

(Ma 2022)

(Kozio-Kozakowska 2022)
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Scientific Dose, Superior Form

D3 + K2 That Actually Works

Unlike other vitamin D supplements, our Vitamin D3 + K2 supplement uses the biologically active form of vitamin D (cholecalciferol), which raises blood levels of the vitamin more effectively and for a longer period than vitamin D2.* 

Making this supplement even more effective is a highly bioactive form of vitamin K2, menaquinone-7 (MK-7). Clinical research shows that MK-7 increases bone mineral density and promotes better bone quality and strength than other forms of vitamin K.*

Expert Reviews

Daniel G. Amen, MD, founder of BrainMD, in his office
“This synergistic combination is so powerful, it’s like sunshine in a bottle and can help support your mood, bone health, immune function, and cognition.”

Dr. Daniel Amen

Founder, BrainMD & Amen Clinics
BrainMD Vitamin D3 + K2: woman's hand holding up capsule with white powder against a blue sky
Two Nutrients, One Powerful Pair

Why D3 Needs K2—And Vice Versa

Research shows vitamin D helps regulate over 2,000 genes and is needed by almost every part of your body to function and thrive. It helps regulate your immune system, aids in calcium absorption, balances your mood, and promotes optimal health.* When paired with vitamin K2, vitamin D3 helps move calcium into your bones (where it’s needed most), which prevents it from forming deposits in your arteries and blood vessels.* Together, this dual-action nutrient combination supports strong bones, a healthy heart, and sharper brain.*
BrainMD Vitamin D3 + K2: woman in yellow dress holds supplement bottle in a field of yellow flowers

What To Expect

Week 1

Vitamin D3 starts raising blood levels of 25(OH)D, supporting immune function and mood balance. Some people notice an early lift in energy and outlook.*
Week 4

Consistent supplementation helps regulate calcium absorption. You may begin to feel steadier energy, stronger immunity, and better recovery from daily stressors.*
2–3 Months

Vitamin D3 + K2 work together to direct calcium into bones (not arteries). Expect noticeable improvements in bone and joint comfort, cardiovascular health, and long-term resilience.*
6 Months+

With sustained use, this powerful combination helps optimize bone density, maintain healthy blood vessels, and strengthen immune defenses year-round—supporting whole-body vitality and healthy aging.*

FAQ

Got questions? We’ve got answers. Explore our FAQs or chat with our AI assistant for instant support.

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Overall rating: 4.904437 / 5 from 293 reviews.

AI Generated Review Summary

Vitamin D3 + K2 capsules are praised for their small size and ease of swallowing, offering great quality and value for money. Customers appreciate the cleanliness and effectiveness of the Vitamin D, and the supplement is noted for its positive impact on energy and stress management. While some users report noticeable improvements, others do not observe significant changes.

Summary topics

  • Capsule Size and Ease of Swallowing (3%): Customers raved about the small and easy-to-swallow capsules, praising their effectiveness and ease of use.
  • Product Quality (11%): Customers expressed appreciation for the great quality of the products, which was mentioned multiple times in the reviews.
  • Value for Money (8%): It was reported by customers that the price of the product is great and offers good value for money.
  • Vitamin D Cleanliness (5%): Customers raved about the Vitamin D, praising its cleanliness and lack of fillers.
  • Daily Supplement Effectiveness (12%): It was observed by customers that this supplement is a great and excellent daily option for their daily routine.

Review topics: ["size","feel","quality","price","improvement","results","amount","supplement","ingredients","benefits","body","vitamins","dose","works","vitamin d","combo","difference","level","capsules","combination","effect","health","absorption","change","pills","brand","mood","service","doctor","brainmd"].

Review highlights

  • "Love this product, high quality, great price and helpful customer service." — Jenna B.
  • "Essential daily supplement and I feel so much better!" — Echo J.
  • "It really makes a difference on how I feel mentally during the winter months." — Marco L.

Reviews

Dynamic Duo

"My primary care physician ordered me to take vitamin D3 , 5000mcg daily for the rest of my life. Fortunately, I did my own research and found that taking K2 was necessary for absorption to receive the full benefits. Instead of separate doses, my supplements are conveniently packed into one easy capsule."

— Peter R. (5/5)

Improved my brain fog

"This was a good-sized pill which is easy to swallow. It arrived on time. Taking it has improved my mood and especially the brain fog I was experiencing. I was able to resume projects I abandoned because I lacked concentration."

— Yared N. (4/5)

Doctor approved

"I have been taking this supplement for a few years and it works well! In fact my doctor looked at the bottle and said that this is a very good D3+K2 vitamin. I know that Dr. Amen’s supplements are the best."

— Nancy C. (5/5)

Vitamin d3 k2

"I especially like BrainMD vitamin d3 k2 because it has a higher amount of k2 and d3 is higher."

— Camille M. (5/5)

This works!

"My and my family love taking this vitamin. Its gently on our stomachs and easily absorbed. We take it with food in the mornings."

— Ashley M. (5/5)

Great Vit D!

"Living in the Midwest means daily vitamin D and this is the best."

— anita (5/5)

Hope it's good

"I've always been told to take Vitamin D in an oil based form but this one is powder. Trusting the brand due to Dr. Amen but I have not had my levels checked yet."

— meagan s. (4/5)

Improved my vitamin D levels with these supplements!

"I was surprised to find out that my vitamin D levels were on the lower end of the nornal range. I spend a lot of time outdoors and they were still on the lower normal range. I started taking these supplements and noticed improvement in my lab results. I trust the quality of these supplements, all Brain MD supplements, I take several different kinds."

— Rodolfina Z. (5/5)

5 Stars

"This is the only fish oil I’ve found that does not make my stomach feel weird. Worth every penny."

— Lindsay N. (5/5)

Seems to be working great

"I love the option of D3 and K2. I hear that’s the best combination and so happy to be able to order all my supplements in one place."

— April D. (5/5)

Q&A