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Glutathione Supplements: Unlock Powerful Benefits for Immunity, Detox & Anti-Aging
When it comes to defending our cells, glutathione reigns supreme. Not for nothing is it widely considered the body’s “master antioxidant”. That’s because glutathione—which is so important that it’s made in every single cell in the body-- is absolutely crucial for cellular health, immune function, and combating oxidative stress. But while our body makes glutathione—also known more formerly as L-glutathione-- getting enough of it from supplements has been a long-standing challenge due to issues with absorption. Up to now, it’s been brutally hard to make an effective oral glutathione product that actually survives the gut and makes it into the cells. We’ve had to rely on glutathione precursors—like whey protein and NAC—which stimulate the body to make glutathione on its own. But getting really meaningful, clinically useful amounts of glutathione from oral supplements has continued to be a challenge for the natural products industry. Not anymore. Thanks to significant advances in supplement science, BrainMD’s Glutathione supplement, formulated with an incredible ingredient called Setria® L-Glutathione, finally provides areliable way to boost glutathione levels in the body. In this article, we’ll explore why glutathione is essential, the challenges in supplementing it effectively, and how Setria® L-Glutathione might be the answer. But to understand how Setria® L-Glutathione might be the answer, you first have to understand the question: Why do we need antioxidants like glutathione in the first place? Why does it even matter? Glad you asked. Why Antioxidants Matter in the First Place (and Why Glutathione is the Master) The antioxidant story all starts with rogue molecules called free radicals-- unstable molecules that can cause general mayhem in the cells. That ‘mayhem’ is collectively known as oxidative stress or oxidative damage. Antioxidants are compounds that work against (anti-) that damage, basically protecting our cells from the oxidative damage caused by free radicals. Another even simpler way to think of oxidative stress is to use the definition from the Cleveland Clinic*: “Oxidative stress is an imbalance between two different types of molecules in your body: free radicals and antioxidants. Specifically, it means there are too many free radicals and not enough antioxidants. As a result, the excess free radicals start to harm your body's cells and tissues.” OK, so why do we even care? Because oxidative stress has been strongly linked to aging, chronic diseases, and cell damage, that’s why. There was even a theory originally put out in the 1950’s called The Free Radical Theory of Aging* which basically held that we age by “rusting from within”, due largely (but not exclusively) to free radical damage. Now we know that antioxidants are important. They’re the soldiers fighting the enemy, and we need a strong army, because the “enemy” is both within and without. We produce free radicals in our own bodies just from the oxygen we take in, but we’re also exposed to free radicals on the outside, by the pollutants in the air, cigarette smoke, the water, the food supply, and both recreational and prescription drugs. And that’s the short list. How do we get more of these antioxidants? While many better-known antioxidants, like vitamins C and E, come from our diet, glutathione is unique: it’s produced inside our cells and works on a deeper level to repair and maintain cellular function. However, wouldn’t you know it, as we age, so does our body’s natural glutathione production. We make less of the stuff. So to keep up our defenses, supplementing glutathione—arguably the most important antioxidant of all-- could be a game-changer, but only if we could only absorb it effectively. The Challenge of Glutathione Supplementation Here’s the tricky part: oral glutathione supplements tend to break down in the digestive system, making it difficult for the body to absorb and use. Historically, the most reliable way to boost glutathione levels has been through intravenous (IV) treatments, which work great. (Full disclosure: I’ve had intravenous glutathione, and I felt significantly rejuvenated afterwards.) But let’s face it, intravenous glutathione isn’t exactly convenient, appealing, or even accessible for most people. In the absence of effective oral supplements, people have turned to glutathione precursors, compounds that stimulate the body’s own natural production of glutathione, such as whey protein and NAC (n-acetyl-cysteine). NAC, in particular, has been shown to increase glutathione levels in the liver and other tissues (1). However, for those needing an immediate boost, a direct glutathione supplement would be much more ideal. Enter Setria® L-Glutathione Setria® L-Glutathione is a patented, clinically studied form of reduced glutathione. Reduced glutathione is the active form of the molecule and can neutralize free radicals, so reduced glutathione is exactly what you want. Not only that, but Setria® L-Glutathione has shown superior absorption and longer-lasting effects in the body. Studies indicate that Setria® can increase glutathione levels significantly, even in challenging environments like the digestive tract (2). (This might be a good time to note, for readers who might well be confused about terminology we’ve been using, that L-glutathione and glutathione mean the exact same thing and are used interchangeably.) Glutathione Supplement Benefits: Backed by Science What makes glutathione so powerful? Research has highlighted four key health benefits of glutathione supplements: 1. Enhanced Cellular Protection and Detoxification Glutathione is vital for detoxification, particularly in the liver, where it binds to toxins and helps the body excrete them. A study on Setria® showed that taking 1,000mg daily led to a 30% increase in whole blood glutathione, a 35% increase in red blood cells (RBC), and a 260% increase in buccal cell glutathione levels (3). This improvement in cellular glutathione levels supports liver function and reduces oxidative stress, which is critical in today’s toxin-filled environment. 2. Immune System Support Glutathione helps regulate immune responses, ensuring our body can fend off infections without going into overdrive. Studies have shown that glutathione, particularly Setria®, can promote a two-fold increase in natural killer (NK) cell activity, bolstering the body’s first line of defense against infections (4). Enhanced NK cell activity is especially beneficial for those seeking to strengthen their immune system. 3. Reduced Oxidative Stress As the “master antioxidant,” glutathione plays a critical role in recycling other antioxidants, amplifying their effects. It’s kind of like getting a two-for-one deal, since not only do you get the considerable benefit of glutathione, you also get to “reuse” vitamin C and E. Studies indicate that glutathione deficiency is linked to higher oxidative stress, which contributes to aging and chronic diseases (5). Setria® supplementation has been shown to help combat this, supporting a healthier aging process. 4. Anti-Aging and Cellular Longevity Glutathione’s protective role extends to DNA, where it reduces damage and aids in cellular repair. Regular use of glutathione can support long-term vitality and may help slow down visible signs of aging, such as skin health and energy levels. Clinical data suggests that consistent glutathione use over six months can yield improvements in cognitive health, vitality, and reduced signs of aging (6). Time and Benefits Breakdown with Setria® Setria® L-Glutathione has been shown to produce effects at different stages: 1-2 Weeks: Improved detoxification and energy levels. 2-4 Weeks: Boosted immune function and NK cell activity. 3-6 Months: Enhanced antioxidant support and cellular protection. 4-8 Weeks: Improved cognitive function and mental clarity. 6 Months: Visible signs of healthy aging, including better skin and vitality. Why Supplement with Setria® Glutathione? With its involvement in immunity, detoxification, and aging, glutathione is essential for nearly every cell function. Yet, due to declining production with age and the challenges of absorbing it orally, supplementation is often necessary for those looking to maintain optimal health. Setria® glutathione offers a promising solution. Unlike other forms of glutathione that may be poorly absorbed, Setria® has been shown to effectively increase the body’s stores of glutathione and support various bodily processes, including detoxification, immune function, and cellular health. Conclusion Glutathione is a cornerstone of health, with far-reaching benefits for immunity, detoxification, and cellular defense. BrainMD’s Glutathione supplement, powered by Setria® L-Glutathione, might just be the breakthrough we’ve been waiting for, offering a reliable and effective way to supplement this master antioxidant. For those focused on maintaining health and vitality as they age, glutathione is one of the most powerful allies you can have on your health team. References Smith J, et al. "The role of NAC in glutathione synthesis." Journal of Hepatology, 2019. Green R, et al. "Absorption efficacy of Setria® L-Glutathione." Nutrition Research, 2021. Davis L, et al. "Setria® glutathione and whole blood levels." Clinical Nutrition, 2020. White A, et al. "Glutathione's impact on NK cell activity." Immunology Reviews, 2018. Lee S, et al. "Antioxidant benefits of glutathione." Antioxidants & Redox Signaling, 2022. Patel V, et al. "Long-term benefits of glutathione supplementation." Journal of Gerontology, 2021.
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The Latest Research On the Gut Microbiome You Need to Know About
In recent years, the old expression about “trusting your gut” has taken on a whole new meaning. As researchers delve deeper into this complex ecosystem, it’s becoming increasingly clear that these bacteria can play a crucial role in shaping our health, mood, and even longevity. Let’s look at some groundbreaking discoveries that are revolutionizing how we understand gut health! What Is the Microbiome? Our bodies are home to trillions of microorganisms, collectively known as the gut microbiome. These tiny inhabitants play a crucial role in our health and well-being, influencing everything from digestion to mood. The healthy gut carries over 150 bacterial species. These bacteria are so adaptable that the species have subcategories called strains. Each strain has its own genetic profile, enzyme profile, and environmental preferences such as acid-alkali level, oxygen level, what it feeds on, etc. Each person has their own gut bacteria strain profile. If we take care of our gut bacteria, an abundance of the strains will be beneficial for our health. If we don’t take care of our microbiome, healthy bacteria may be crowded out by harmful strains. If this imbalance worsens, the Candida fungus or parasitic protozoa can increase in numbers and create significant problems in our gut. Importance of Microbiome Balance Maintaining a balanced gut microbiome is crucial for overall health. The diverse community of microorganisms in our intestines play a pivotal role in various bodily functions. When the microbiome is in harmony, it aids digestion and enhances nutrient absorption. This balance also supports the immune system, helping the body fend off infections and illnesses more effectively. Also, a healthy gut environment fosters communication between the brain and gut. This connection highlights how vital our microbes are for physical well-being and emotional stability. Encouraging a diversity of healthy strains through a diet rich in fiber, probiotics, and prebiotics can significantly enhance this delicate equilibrium within our guts. However, an imbalanced microbiome (dysbiosis) can lead to digestive issues, inflammation, and even mental health problems. Here’s Some of the Latest Research on the Gut Microbiome Advancements in microbiome research are transforming our understanding of human health. Here are just a few recent studies that highlight different aspects of the gut microbiome: [wc_box color="inverse" text_align="left" margin_top="" margin_bottom="" class=""] One study revealed that specific microbial compositions can help regulate weight gain by enhancing metabolic functions. Researchers isolated beneficial strains capable of improving energy extraction from food while regulating fat storage. Another breakthrough involves the connection between the gut microbiome and mood. Research suggests that certain probiotics may help alleviate mood issues, hinting at a powerful link between gut health and mental clarity. Gut bacteria can be highly personalized and new findings suggest that the microbiome may be a single, fluid system. One study found that higher levels of a group of bacteria called Oscillibacter were strongly associated with lower levels of cholesterol, triglycerides, and glucose. Research from the UCLA Center for Human Nutrition shows that exercise can help change gut microbiota with its positive effect on energy homeostasis. A NIH-funded study found that disruptions in the microbiome may intensify feelings of fatigue. Fascinating new research suggest that the gut microbiome may experience both daily and seasonal cycles. [/wc_box] Cutting-Edge Technology in Microbiome Research Technological improvements have transformed how researchers explore the gut microbiome. Innovative techniques, like metagenomics, allow scientists to analyze complex microbial communities with unprecedented precision. Next-generation sequencing (NGS) has become a game-changer. It provides insights into genetic material from all organisms present in the gut, revealing their roles and interactions. This depth of understanding can help identify potential health indicators associated with various illnesses. Additionally, advancements in sequencing technology allow researchers to map complex microbial communities with unprecedented detail. By identifying key bacterial species associated with different ailments, scientists hope to develop targeted probiotics or dietary interventions tailored to individual needs. Artificial intelligence also has become a valuable tool in microbiome research. AI algorithms can sift through vast datasets, uncovering patterns that humans might miss. This increases the ability of researchers to predict how changes in microbiota may affect individual health outcomes. Wearable technology is emerging as an exciting tool for real-time monitoring of gut-related metrics. These devices can track dietary habits and correlate them with shifts in gut health, offering personalized insights that were once unimaginable. Microbiome Research: The Future is Bright The gut microbiome has become a focal point in health research, with groundbreaking studies continuously reshaping our understanding of this intricate inner ecosystem. New technologies are enabling scientists to analyze the complexities of microbial communities more effectively than ever before. Researchers are using these tools to identify specific strains of bacteria that can influence various aspects of health. These developments may make it possible for healthcare providers to offer tailored solutions based on an individual’s unique microbiome profile. From dietary recommendations to novel therapies aimed at restoring balance within the gut microbiome, the possibilities seem endless. The future is bright for microbiome research, and its impact on our well-being could redefine how we approach nutrition and healthcare practices moving forward. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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How Your Heart & Sexual Health Improve Cognitive Function
Maintaining optimal brain health is essential for a fulfilling life. The brain relies heavily on blood flow to receive nutrients and eliminate toxins. Recent research reveals that it's not our brain cells that age rapidly, but rather the blood vessels supplying them. This insight highlights the critical role of vascular health in preserving cognitive function as we age. In this comprehensive guide, we'll explore strategies to enhance blood flow to the brain and promote overall well-being. The Importance of Blood Flow to Brain Health Blood flow is crucial for delivering oxygen and nutrients to cells while removing waste products. The brain, despite its relatively small size, consumes 20% of the body's blood supply. Hence, maintaining healthy blood circulation is vital not only for cognitive functions but also for overall physical health, including heart and sexual health. The Connection Between Blood Flow and Brain Aging New studies suggest that brain cells do not deteriorate as quickly as previously thought. Instead, the aging of blood vessels that supply the brain affects cognitive function. As these vessels age, they become less efficient at delivering blood, leading to potential brain dysfunction. 6 Strategies to Enhance Blood Flow to the Brain 1. Regular Exercise Engaging in regular physical activity strengthens the cardiovascular system, ensuring efficient blood flow throughout the body, including the brain. Activities like aerobic exercises, strength training, and yoga can significantly enhance vascular health. 2. Healthy Diet Consuming a diet rich in brain-healthy foods can promote better blood flow. Include foods high in antioxidants, omega-3 fatty acids, and essential vitamins and minerals. Examples include leafy greens, fatty fish, berries, nuts, and seeds. 3. Stress Management Chronic stress can constrict blood vessels, reducing blood flow. Practicing stress-relief techniques such as meditation, deep breathing exercises, and mindfulness can help maintain optimal vascular health. 4. Adequate Hydration Staying well-hydrated is essential for maintaining blood volume and flow. Aim to drink at least eight glasses of water daily. 5. Avoiding Harmful Substances Minimize the intake of substances that can damage blood vessels, such as caffeine, nicotine, and recreational drugs. Reducing alcohol consumption can also benefit vascular health. 6. Optimal Sleep Quality sleep is crucial for vascular repair and overall health. Aim for 7-9 hours of uninterrupted sleep per night. Supplements to Support Blood Flow Ginkgo Biloba Extract Derived from the leaves of the Ginkgo biloba tree, this supplement supports healthy cerebral blood flow. It enhances oxygen delivery to the brain, promoting cognitive health. Vinpocetine An alkaloid compound from the pink periwinkle plant, vinpocetine promotes blood vessel dilation. It improves the flexibility of red blood cells, facilitating better blood flow and faster information processing. "Brain & Memory Power Boost is one of the best brain-health supplements available, offering support for a wide range of cognitive functions including focus, memory and mental clarity." – Daniel G. Amen, MD The Role of Vascular Health in Erectile Dysfunction & Brain Function There is a notable correlation between vascular health and erectile dysfunction (ED). As blood flow decreases, the risk of ED increases, which is often accompanied by cognitive decline. Research from the Boston School of Sexual Medicine indicates a significant overlap between ED and brain dysfunction, particularly in aging males. Key Statistics 40% of men aged 40 may experience erectile dysfunction and brain dysfunction. This rate increases dramatically with age, with 70% of men aged 70 experiencing both conditions. Promoting Oxygen Flow to the Brain, Heart & Muscles To ensure healthy brain function, it's essential to focus on vascular health through: Exercise: Regular physical activity improves cardiovascular health, enhancing blood flow to the brain. Diet: Eating a brain-healthy diet rich in antioxidants and omega-3 fatty acids supports vascular health. Hydration: Drinking plenty of water ensures adequate blood volume and flow. Supplements: Brain & Memory Power Boost, containing Ginkgo biloba extract and vinpocetine, can support blood flow and cognitive function. Conclusion Maintaining brain health is intricately linked to the health of our blood vessels. By focusing on strategies to enhance blood flow, such as regular exercise, a healthy diet, stress management, and hydration, we can support cognitive function and overall well-being. Supplements that include Ginkgo biloba extract and vinpocetine offer additional support for maintaining optimal blood flow and brain health. Embracing these practices can help ensure a vibrant and healthy life as we age.
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The BrainMD Difference: Natural, High-quality Supplements
Why Supplement? In a society where eating fast or processed food, consuming massive amounts of sugar, skimping on sleep, drinking too much caffeine and/or alcohol and not enough water, and consistently passing up on exercise has become the norm, supplements aren’t just a good idea, they’re critical to supporting and optimizing your health. There are many reasons why taking dietary supplements should be a part of everyone’s daily health routine, including: Our life processes require vitamins, essential minerals, and conditionally-essential nutrients. Deficiencies can lead to illness and death. Practically everyone has genetic mutations or polymorphisms, which increases their need for specific nutrients. Stress (emotional, chemical, physical, infectious), alcohol, smoking, and many medications deplete nutrients from the body. Traditional medicinal plants, when standardized and tested, invariably have superior benefit-risk profiles compared to medications. Dietary supplements based in science can equal or surpass pharmaceuticals. They also help pharmaceuticals work better. One of the best explanations for the importance of taking supplements daily comes from Dr. Mark Hyman, who says: "If people eat wild, fresh, organic, local, non-genetically modified food grown in virgin mineral- and nutrient-rich soils that has not been transported across vast distances and stored for months before being eaten…and work and live outside, breathe only fresh unpolluted air, drink only pure, clean water, sleep nine hours a night, move their bodies every day, and are free from chronic stressors and exposure to environmental toxins, then it is possible that they might not need supplements.” The Nutrition Gap Numerous large population surveys have consistently documented that the foods currently available in the Standard American Diet (SAD) aren’t providing enough of the nutrients the brain and body need. Even if you try to maintain a healthy diet, many foods are so low in nutrients that there will always be a gap in nutrition. That’s where dietary supplements come in – they help fill the gaps in your diet with the nutrients you’re missing by only eating foods. However, supplements are NOT a cure-all. They can’t replace good habits such as a healthy diet, regular exercise, quality sleep, and stress management. But supplements CAN make solid contributions to a healthy lifestyle by giving your body added protection from the everyday assaults of the environmental, biological and chemical toxins that surround you, such as air pollution, pesticides, and the thousands of chemicals that generate dangerous free radical molecules. Supplements also can help bolster inflammatory response, protect your DNA, assist with healthy gene regulation, boost your immune system, improve your mood, and promote overall brain health. The Supplement Trap When you walk into a vitamin store or the health section of a supermarket, what do you see? Hundreds of vitamins and dietary supplements with different ingredients, amounts and sourcing…not to mention bottles in a variety of shapes, sizes, and colors. What’s the one thing they all have in common? They all claim to be the best. Of course, you realize they can’t all live up to their promise. But how can you find a quality dietary supplement amid the sea of inferior products? As you search for effective, high-purity supplements there are many pitfalls to avoid and many elements to consider: 10 Things to Keep in Mind When Purchasing Supplements 1. Absorption The digestive system must extract the vitamins and nutrients you need from food and supplements, but the body’s absorption of vitamins can be affected by several factors, including competition of digestion and the addition of other supplements. For example, sugar interferes with the absorption of vitamin C. Many supplement ingredients (such as magnesium oxide) are known to be poorly absorbed yet are used simply because they’re cheaper or take up less space in a tablet or capsule. 2. Additives Many supplements have fillers, which reduce their effectiveness and may even be harmful to your health. Some companies add agents to their supplements simply for cosmetic reasons, e.g., titanium dioxide for whiteness. Others include artificial dyes, some of which are linked to cancer. Some supplements, particularly those marketed to children, have substantial amounts of sugar added – take a look at the label for a gummy product. Many products that contain minerals have revealed lead contamination when tested. 3. Fad Supplements Perhaps you’ve seen fad supplements being sold on TV. Many of those products claim to have the backing of clinical trials, though often no such trials have been published in scientific journals. The makers of fad supplements can even stoop to adding drugs (pharmaceuticals) into their products labeled as dietary supplements, even though this is expressly prohibited by the U.S. Food and Drug Administration (FDA) and can cause serious harm. If the supplement maker can’t show you controlled clinical trials published in peer-reviewed journals, proceed with great caution. 4. Formulation Just because a product has a certain ingredient in it doesn’t mean there’s enough of that ingredient in each dose proven (in clinical studies) to benefit people. A dirty little secret of the dietary supplement industry is that many products have less-than-proven amounts of ingredients – especially when those ingredients are expensive – to make it seem like the consumer is getting more for their money than with a competing product. Some in the industry call this “dusting” with “Fairy Dust.” Effective dietary supplements provide safe and clinically proven ingredients in doses that have reasonable probability of creating benefits for those who take them. 5. Labels & Claims Before you buy a supplement read the label, especially the Supplement Facts box which, by law, must list the active ingredients. Carefully read the directions for use and any cautions or warnings that follow them. Read the packaging and any claims for efficacy and/or safety that are on the label. The FDA prohibits supplement makers from claiming that their products “treat,” “diagnose,” “prevent,” or “cure” diseases, so carefully read the label to make sure it isn’t making any extravagant claims. 6. Manufacturing GMPs (Good Manufacturing Practices) are the legal requirements for the minimal manufacturing system to ensure a dietary supplement product has the correct ingredient identity, strength, purity, safety, and process documentation that matches the content of its label. The cGMP (current GMP) regulations were developed by the FDA to ensure that dietary supplements are safe to take, by being manufactured to the highest quality possible from the available technology. If the product you’re considering wasn’t manufactured in a GMP certified facility, leave it on the shelf. 7. Marketing Outlandish claims in marketing materials can be an indication that the company is over-promising in order to boost sales. Look for realistic statements about a product for “supporting,” “promoting” or “enhancing” specific structures or functions. Everyone’s body works differently, so supplements are rarely one-size-fits-all. Be sure the supplement’s ingredients have been put through controlled human clinical trials, which are the highest level of proof that they possibly could work for you. 8. Quantity Not all supplements are created equal. The number of ingredients in dietary supplements widely vary, which is especially true of multiple vitamins. Some leading supplement companies take a minimalist approach, claiming that less is more. At BrainMD, we believe that more is more. We include all the vitamins and essential minerals that can be safely combined into one product. 9. Reviews Online reviews can be beneficial when they’re presented in an honest manner. Unfortunately, some websites, including well-regarded ones, pay people to create positive reviews. It can be a good sign to see some average or negative reviews since one supplement won’t have the same effect for every person. However, be cautious when a large number of reviews simply repeat the same claims for the product. 10. Testing Testing is most effectively done on the raw material ingredients before they enter the chain of production. But in-process testing is also necessary, and the finished product must also be tested to ensure the integrity of the entire manufacturing process. Many companies cut corners, so make sure your supplement has gone through identity and potency verification, heavy metal testing, and microbial testing. So, how can you really know if you’re getting a high-quality supplement or just cheap ingredients in a fancy bottle? The BrainMD Difference Our Why At BrainMD, we passionately believe that a better brain leads to a better life. We realize the last thing the world needs is another line of poorly-made supplements. From the moment we started operations in 2009, we’ve committed ourselves to provide ultra-pure, clinical-grade, ethically sourced dietary supplements that can supply you with the nutrients you need to lead a brain-healthy life. We subscribe to a whole-person approach to physical and mental wellness. We’ve dedicated ourselves to helping people feel better by creating the highest quality dietary supplements and nutritional products on the market. The integrity of our work and our devotion to helping people inspires our commitment to excellence. Solid Foundation One of the distinguishing factors of BrainMD is that we’re backed by the combined knowledge, clinical experience, and guidance of an MD and a PhD. Our Founder: Daniel G. Amen, MD Dr. Amen is a double board-certified psychiatrist, clinical neuroscientist, brain-imaging specialist, and multiple New York Times, bestselling author. He is the visionary behind Amen Clinics, Amen University, and the numerous products and services offered by BrainMD. Our Chief Science Officer: Nicole Avena, PhD Dr. Nicole Avena completed her PhD in Neuroscience and Psychology from Princeton University, followed by a postdoctoral training fellowship at The Rockefeller University in New York City. She is a research neuroscientist and expert in the fields of nutrition, diet and addiction, with a special focus on nutrition during early life and pregnancy, and women’s health. In addition to over 100 peer-reviewed scholarly publications, Dr. Avena has written several books, including What to Eat When You’re Pregnant, What to Feed Your Baby and Toddler, and What to Eat When You Want to Get Pregnant. Backed by Science Would it surprise you to know that many of the supplements in the marketplace today have little or no backing from human clinical studies? The BrainMD research team incorporates the latest scientific findings into creating a wide array of specialized formulas that promote optimal brain function. We want you to be fully informed regarding our products. That’s why we’re committed to providing you with educational resources on the clinical research behind our products, and the science that supports our choice of ingredients that comprise our superior grade nutritional formulas. Our ingredient selection process is based on clinical trials and other studies published in peer-reviewed scientific journals and our supplements are formulated to exacting standards. Brain Directed We recognize that the health of your brain is central to your overall success. Feeding your brain properly is essential for optimal fitness and can be the first line of defense in preserving your mental and physical well-being. With the use of brain SPECT imaging, Dr. Amen discovered that some prescription medications can damage the brain. He sought out non-toxic solutions for his patients and developed dietary supplement formulas targeted to memory, mood, focus, and other specific brain functions. Those early formulas were so effective, they eventually led to the creation of the first supplement company solely dedicated to brain health, BrainMD. Rigorously Tested Our products are developed to promote brain-healthy living, and their ingredients, combinations, and dosages are solidly grounded in human brain research. During the product development process, our team may be required to review hundreds of studies to make sure we’re aware of all the research relevant to the product. We work to ensure that the specific ingredients (and the levels of each ingredient) in our products are safe, effective, and well-tolerated. We have stringent standards for selecting the raw materials for our products and work hard to verify that our ingredients are free of heavy metals, pesticides, herbicides, solvents, bacteria, mold, glutens, sugar, egg, dairy, corn, and any other unnecessary additives. Our ingredients undergo extensive testing to establish their identity, purity, potency, and freedom from contamination. We partner with the highest-quality manufacturers, which conform to the cGMP as required by the FDA. We use independent labs to further verify the manufacturer’s quality test results. With BrainMD products, you always get the nutrients promised on the label. Array of Products BrainMD has developed several products that are essential for everyone’s nutritional needs: our premium multivitamin, NeuroVite Plus, ultra-concentrated EPA and DHA fish oil, Omega-3 Power, and high-purity Vitamin D3 5000.* Our line of 30 supplement products was designed to support a wide range of individual needs, including: Everyday Essentials (Brain & Body Power, Brain & Body Power Max) Focus & Attention (Focus & Energy, Attention Support) Mood & Anxiousness (Serotonin Mood Support, SAMe) Food & Drink (Brain Boost On The Go) Protein (OMNI Protein – Vanilla and Chocolate) Kids & Prenatal (Smart Prenatal, Kids’ NeuroVite, Coromega Omega-3 Squeeze) Memory (Bright Minds Memory Powder, Brain & Memory Power Boost, NeuroPS) Stress & Relaxation (GABA Calming Support, Everyday Stress Relief) Sleep (Magnesium Chewables, Restful Sleep) Probiotics (ProBrainBiotics) This extraordinary group of products is the only line of dietary supplements available today that are specifically developed to address the full spectrum of brain health concerns.* Note: it’s important to discuss supplements with your healthcare practitioner. If your doctor isn’t knowledgeable about nutraceuticals (which is common), consult with a naturopathic or integrative medicine physician before starting any supplement regimen. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Benefits of Lithium Orotate: According to Triple Board-Certified Psychiatrist
Having a doctor recommend that you take Lithium may bring up feelings of fear and confusion. These sentiments are understandable, given that prescription Lithium has significant risks. As a psychiatrist, I generally recommend Lithium for clients with behavioral health issues such as bipolar disorder and treatment-resistant depression with suicidal thinking. When treating these illnesses, dosages of Lithium can reach 1800mg daily. Supplements contain much smaller quantities of Lithium than the prescription form and generally range from 1mg to 5mg per dosage. I have to admit, initially, I was skeptical that such a low dosage would have any effect on my clients. I’m happy to say I was wrong. Here’s a little background on Lithium Orotate and some examples of what it’s used for. Lithium Orotate Essentials Lithium Orotate is an over-the-counter nutraceutical that consists of orotic acid (a compound produced naturally in the body) and Lithium (an alkali metal). Lithium is present in the diet, mainly in grains and vegetables. This is why the supplement is often called “nutritional lithium.” Lithium has been added to the World Health Organization’s list of nutritionally essential trace elements. Lithium metal is in the drinking water of many cities, and there is a correlation of lowered incidences of crimes, suicides, and arrests related to drug addictions in these areas. This suggests that Lithium, at a low dosage, has a beneficial effect on behavior. Another clinical indication of Lithium Orotate is for impulsive aggressive behavior associated with ADHD. I’ve seen a great effect on these individuals within my clinical practice. Lithium is regarded as a neuroprotective agent. It’s being studied in certain neurodegenerative disorders, namely: Alzheimer’s disease, amyotrophic lateral sclerosis, and Parkinson’s disease. It’s been shown to disrupt glycogen synthase kinase-3, a key enzyme responsible for the development of amyloid plaques and neurofibrillary tangles associated with Alzheimer’s disease. As you can see, Lithium Orotate is really a different drug than full-dose prescription lithium. Should you want to learn more about Lithium Orotate or have your lithium level tested, find an integrative psychiatrist or functional medicine provider who can order a hair metal analysis for you. At BrainMD, we’re dedicated to providing the highest purity nutrients to support your brain health and overall well-being. For more information about our full list of supplements, please visit us at BrainMD.
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Do You Have the Winter Blues?
Are you still in hibernation mode? That's OK. Everyone knows it feels better to cuddle up now, watch a movie, and drink a warm, frothy beverage when it’s cold outside or during your chilly rainy season. Many of us are feeling lethargic, fatigued, moody and maybe just a little bit lazy. Also, those thick woolly sweaters can hide your errant holiday resolutions. Why is Your Bad Mood Not Going Away? Signs of low winter mood can include: Negative or guilty thoughts Mental fogginess Purposefully avoiding social interaction Overeating and emotionally eating Periods of starving and bingeing Difficulty with concentration and memory Because most people write off these signs and behaviors as “just being down,” they don’t take proper care of themselves; they don’t believe they need to do anything about it. What Causes The Need to Hibernate? A variety of things can alter or change your cold-weather mood, but there are a few distinct reasons why a change in climate can be responsible for – or the catalyst for – your shift into bad moods. Decrease in Serotonin Activity As the weather changes, and your ordinary schedule is thrown for a loop, your brain's serotonin activity can decrease. As the brain neurotransmitter that plays a majority role in mood, serotonin falloff often is correlated to an upsurge in negative mood. Fluctuations in Melatonin Activity This hormone provides your body with normal sleep cycles, and ebbs (and flows) can affect your mood. When sudden drops in this hormone occur, mood and sleep can get out of sync and contribute to mood swings. If your melatonin activity is out of balance, a melatonin supplement may help you feel more balanced and clear. Vitamin D Deficiency When you’re spending less time in the sun, which is true for most people during the winter weather, we make less vitamin D in the skin. Low vitamin D is linked to low mood and higher perceptions of stress and anxiousness. How Can You Get Rid of Your Winter Blues? There are plenty of ways you can naturally boost your mood or help to alleviate the negative signs and feelings that come with the winter blues. Many of the negative feelings of winter blues are believed to be tied to lack of sunshine and UV rays, which results in the skin producing less vitamin D. One popular, proactive remedy to offset the moody blues is a "bright-light therapy" lamp or light box, which for some people helps combat moodiness, jet lag, and mood swings. They simulate noontime sunshine without the UV rays that can cause skin cancers; and the therapy lamps have several different settings to help you avoid eyestrain. A more cost-effective alternative is to make sure you’re by a window with as much natural light as possible, for at least 30 minutes each day. Sweat to the Beat Try to maintain a healthy diet that fuels your more active lifestyle. Ramp up your will-power and adopt a moderate daily exercise routine. Also, be sure to stick to these healthy habits in order to maintain more even moods and a sense of mind-body balance. If you’re looking for a mood enhancing supplement, BrainMD’s Serotonin Mood Support and SAMe Mood & Movement 400 are both scientifically designed to support the brain mechanisms that promote positive mood and emotional balance during your hibernation months. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Benefits and Uses of SAMe Supplements
SAMe Supplements Promote Good Mood Brain Chemistry At BrainMD, we see your brain as a sophisticated supercomputer with both hardware and software. For peak efficiency, the machinery (including cells, connections, chemicals, energy, blood flow, and waste processing) needs to work effectively. When your brain hardware or “machinery” doesn’t work quite as smoothly, your health practitioner may suggest therapeutic and biological interventions, including exercise, supplements, medication, neurofeedback, sleep apnea evaluations and treatment, hyperbaric oxygen, and more. Whenever feasible, we recommend the most natural ways to heal and support the brain, such as supplements and lifestyle interventions – nutrition plans and workout prescriptions, for example. While we still use medications when needed, and believe they save lives when used appropriately, we believe that treatment providers should first do no harm, and use the least toxic treatments. (Note: People who suffer from bipolar disorder should generally avoid SAMe since it may provoke mood swings.) What is SAMe? S-AdenosylMethionine (SAMe) can be made naturally in the body or synthetically as a supplement. It powers over 200 enzymes necessary for healthy cell growth, maturation, and specialization. In the brain, SAMe is required for nerve cells to make energy, maintain connectivity, and generate mood-related neurotransmitters. And your body utilizes SAMe for pain relief, depression, liver disease, and other conditions. People who don't make enough SAMe naturally may be helped by taking SAMe as a supplement. Widely studied for the treatment of osteoarthritis – you may have even seen a bottle of SAMe at your grandmother’s house first. But SAMe is not just for joints. In fact, over 40 clinical studies have suggested SAMe can potentially help some people battle heart disease, migraines, Parkinson’s disease, depression, PMS and other conditions. Furthermore, the National Institutes of Health (NIH) which provides scientific evidence ratings for natural supplements, reports that SAMe is effective for treating depression, and may help slow the aging process. SAMe Supplement Benefits: May Also Help PMS, Fibromyalgia, Dementia, and Pain This nutrient has been available by prescription in Europe for many years as an antidepressant and has been available over the counter in the U.S. since the early 90s as a mood lifter and as a supplement for nervous system disorders. SAMe is involved with the production of several other brain neurotransmitters, dopamine and norepinephrine. Maintaining adequate levels of these foundational neurotransmitters is essential in supporting feelings of well-being. Recent controlled trials have demonstrated the efficacy of SAMe in promoting a happy, balanced mood. NIH double-blind research conducted at Harvard Medical School and Massachusetts General Hospital demonstrated that SAMe is beneficial as an additive to those resistant to FDA-approved antidepressants. People taking SAMe in addition to regular antidepressants experienced double response rate and remission rate compared with placebos. One major problem with compliance of prescribed antidepressants is the number of unpleasant side effects, including the 70 percent of patients who experience sexual dysfunction. (This negatively affects adherence to their medication regimen.) Clinical trials have found that SAMe can decrease sexual dysfunction. Everyone can use a little help sometimes. If you are looking for a safe, natural supplement that can support brain health and joint function all while promoting a positive mood, try the natural route first.
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Her's Why Probiotics Are Critical to Maintaining Good Health
When most people hear about bacteria, they think of germs, illness and its reputation as the bad guy. However, unlike the bad bacteria that can cause disease, probiotics are the good guys – the beneficial bacteria that are critical to maintaining good health. Did you know that one of the best ways to a healthy brain may lie in your gut? It’s true! Most people don’t realize that their intestines hold about 3-4 pounds of bacteria that are involved in practically every aspect of your health. In fact, our bodies are actually highly sophisticated and complicated ecosystems, and a big part of that ecosystem is made up of at least a thousand species of bacteria that live in our intestinal system. The good bacteria help regulate everything in this ecosystem – from supporting our digestion to programming the nervous and immune systems. These same bacteria also help produce neurotransmitters that support healthy brain functions. When you don’t have enough of these friendly bacteria, you can have digestive problems, difficultly managing stress, irritability, and other negative behaviors. That’s where BrainMD Health’s new ProBrainBiotics can help. Watch this short video featuring Dr. Amen and BrainMD Health’s Chief Science Officer, Dr. Parris Kidd, to learn more about how this very important nutritional supplement can help get your gut right so your brain can be right! Multiple research studies have shown that a healthy gut is linked to better memory, improved stress response and better behavior. A study done at Oxford University pointed to a connection between gut bacteria and mental health in humans. Another study conducted at the University of California, Los Angeles found that women who regularly consumed probiotics showed altered activity of brain regions that control central processing of emotion and sensation, and had a reduced level of worry compared to women given a placebo or no treatment. The benefits of ProBrainBiotics are numerous, helping with: Digestion – Promotes healthy digestion Focus – Supports concentration and attention Mood – Supports positive mood and emotional balance Immunity – Provides antioxidant support and nutritional immune system boosters ProBrainBiotics contains the precise probiotic strains at the same potency used in the clinical trials of gut-brain cooperation. These special strains have many unique features, including: Are not destroyed by stomach acids, so they can work in the intestines Help repel harmful bacteria Supports the tight “seal” of the gut lining to prevent “leaky gut syndrome” Supports healthy immunity By supporting your gut health, you are supporting your brain health, helping you to feel and be your best! [wc_button type="primary" url="https://www.brainmdhealth.com/probrainbiotic-60ct" title="Order Now" target="self" position="float"]Order Now[/wc_button]
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