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8 Premium, Branded Ingredients in BrainMD Supplements
When you walk into a vitamin store or the health section of a supermarket, you’ll see hundreds of vitamins and dietary supplements with different ingredients, amounts, and sourcing. But how can you really know if you’re getting a high-quality supplement or just a fancy label with cheap ingredients? There are many things to look for when purchasing a supplement, such as absorption, formulation, manufacturing, and testing. One way to help ensure you’re getting a quality product is to purchase supplements with branded ingredients. What Are Branded Ingredients? Branded ingredients are special, often proprietary, ingredients that are given a brand name by the manufacturer. These ingredients are also referred to as patented or trademarked ingredients and appear on supplement labels with symbols such as ™ or ®. When an ingredient is trademarked, it usually means the company has invested a great deal of time and money into establishing its quality and elevating its status among other ingredients of its kind. An ingredient might be branded due to its safety or purity or because of the way it’s processed (to be more bioavailable, have better taste, etc.). Benefits of Branded Ingredients Here are some of the top benefits of branded ingredients… Credibility Trademarked ingredients are typically backed by science and have head-to-head comparisons with generic versions, and sometimes even with other branded versions. When the science supports a manufacturer’s claims, it helps establish the ingredient’s quality and credibility. Efficacy Manufacturers of branded ingredients are under contract to their suppliers and must include the ingredient in the way the contract and scientific studies stipulate. Compliance is necessary to ensure the efficacy of the ingredient and to instill confidence in the consumer. Transparency Increasingly, consumers are demanding to know the traceability of the ingredients in the supplements they purchase. A well-researched branded ingredient can help provide transparency, educate the consumer, and offer higher manufacturing standards than its generic ingredient counterparts. Note: Due to the extensive research and financial investment required to formulate and manufacture branded ingredients, they typically cost a little more than supplements with non-branded ingredients. So, does BrainMD have any branded ingredients in its supplements? Glad you asked… 8 Premium, Branded Ingredients in BrainMD Supplements 1. affron® Standardized Saffron Extract A highly concentrated, standardized saffron extract, affron® is found to improve mood, anxiousness, and sleep quality in double-blind, randomized, placebo-controlled clinical trials. This highly concentrated and standardized nutraceutical extract of saffron is a spice that’s been used in the Middle East for at least 2600 years. Modern clinical research with this specific ingredient fully supports the traditional reverence for saffron’s mood-elevating effects. Which BrainMD supplement features this branded ingredient? Happy Saffron Plus was scientifically designed to promote a positive mood. It brings together nutraceutical preparations of the two most traditionally revered “happiness herbals” – saffron flower extract and curcumin from turmeric root – with zinc, a mineral essential for life and vital for a positive mood. 2. Ferrochel® Ferrochel® is a high-purity ingredient of iron atoms bonded to molecules of the amino acid glycine. Unlike iron sulfate, and many other iron compounds used in iron supplements, this form of iron is very gentle on the stomach. Though iron’s main health benefits are typically linked to hemoglobin, this essential mineral aids in energy production, gene regulation, and the body’s detoxification process. Which BrainMD supplement features this branded ingredient? Iron Advanced Ferrochel® Iron is so reactive, it can degrade other supplement ingredients. That’s why BrainMD offers iron as a standalone supplement, in its best tolerated and best absorbed form: ferrous bisglycinate, Ferrochel®. 3. Longvida® Optimized Curcumin Extract The turmeric root has paralleled saffron as an herbal greatly revered for its wide range of benefits for at least 2600 years. Consuming turmeric root doesn’t get much curcumin into the bloodstream, but nutraceutical technology has now overcome this problem. The Longvida® curcumin preparation features excellent absorption of curcumin and has worked well in clinical trials at 400 mg per day or higher. Besides being found to improve mood in clinical trials, Longvida® was recently shown to improve aspects of memory as well. Which BrainMD supplements feature this branded ingredient? Happy Saffron Plus & Brain Curcumins Brain Curcumins provides the three major curcumins as the Longvida® preparation, which is efficiently absorbed. Longvida® helps fight physical fatigue and helps maintain healthy mood and cognitive functioning while under mental strain. 4. Pycnogenol® Maritime Pine Bark Extract Pycnogenol® is a powerful antioxidant concentrate that promotes the delivery of blood to the brain. Intensive clinical research has established its benefits for attention and other higher brain functions in kids as well as adults. This authentic, standardized polyphenol extract comes from the French maritime pine (Pinus pinaster). Pycnogenol® is one of the most extensively researched of all herbal antioxidants. Which BrainMD supplement features this branded ingredient? Attention Support can help increase your attention span while helping you stay relaxed and calm. Its ingredients were picked for their clinically demonstrated benefits for attention, concentration, calm, and overall self-control. 5. Relora® Relora® is a proprietary botanical complex that’s been clinically tested to support calmness. In a double-blind clinical trial, this patented blend of two herbs, Magnolia officinalis and Phellodendron amurense extracts, reduced occasional feelings of anxiousness and stress in premenopausal women. Relora® can help enhance healthy management of the stress hormone cortisol, while easing apprehension, tension, worry, anger, fatigue, negative mood, and confusion. Which BrainMD supplement features this branded ingredient? Everyday Stress Relief was specifically formulated to help replenish your brain and body’s nutrients that can be depleted during times of excessive stress. This supplement includes herbal extracts clinically shown to have calming and anti-stress effects, helping you to feel less anxious without making you sleepy. 6. Satiereal® Saffron Extract Satiereal®, a patented extract of saffron, contains four compounds that have powerful antioxidant, brain-protective, and serotonin-enhancing actions. Saffron, which grows mainly in Europe and the Middle East, has been shown to benefit mood and memory. In clinical trials, Satiereal® was found to reduce feelings of hunger, while supporting appetite moderation and healthy weight management. Which BrainMD supplement features this branded ingredient? Serotonin Mood Support can help increase the production of soothing brain waves, correct stress-related nutritional deficiencies, and promote relaxation that will enable quality sleep. It contains a patented form of saffron (Satiereal®) along with other key nutrients that help to promote relaxation, positive mood, serotonin balance, and even healthy weight management. It can help you handle the ups and downs of life with more composure. 7. Sensoril® Ashwagandha Extract Ashwagandha (Withania somnifera, root/leaves) is a well-known herb that’s been used for centuries in Ayurvedic medicine. Ashwagandha is an adaptogen that supports the body’s healthy response to stress by promoting calm and overall mental focus and has been associated with improved memory. Sensoril® is a highly concentrated, standardized form of ashwagandha. It’s been clinically studied for its mood- and memory-boosting properties. Which BrainMD supplement features this branded ingredient? Focus & Energy was designed to promote sharpness and improve productivity without lowering blood sugar. It’s formulated specifically to reinforce the brain and the body’s ability to fight fatigue and adapt to stress. Focus & Energy includes standardized, ultra-pure extracts of three powerful adaptogens: rhodiola, ashwagandha, and ginseng. 8. Vitakelp® This cold-water, brown seaweed is sustainably harvested off the Scottish Hebrides. It’s a good source of minerals, especially potassium, calcium, and magnesium. It also contains ascophyllan, a unique sulfur-containing carbohydrate that has immune activity. Which BrainMD supplement features this branded ingredient? Neuro Greens Superfood was developed from the latest scientific research on superfoods (foods especially rich with nutrients and other substances beneficial to human health). Neuro Greens includes diverse substances that can help detoxify and energize the body, while providing substantial immune support. It also promotes healthy digestion from its contribution of prebiotic fibers, which support friendly bacteria (probiotics) in the gut. While only some of BrainMD’s supplements contain branded ingredients, all of our dietary supplements are ultra-pure, science-based, and brain directed. Our high-quality supplements come from the finest sources, have undergone rigorous clinical testing, and have been formulated for maximum absorption to give you the nutrients you need to be your best self. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Methods for Relaxation: 5 of the Best Ways to Keep Calm!
Knowing how to relax is practically a superpower in today’s challenging world. Since the start of the pandemic two years ago, people everywhere have become significantly more anxious and stressed. A review from October 2021 analyzed multiple studies from around the world and estimated that anxiousness levels increased 25.6% globally since early 2020. The American Psychological Association’s “2021 Work and Well-being Survey” reported that 71% of participants experience work-related stress during the workday. When was the last time you relaxed deeply? If it’s been a while since you’ve relaxed, or if you have trouble unwinding in general, don’t worry. There are proven methods for relaxation that you can learn. The Body’s Relaxation Response Did you know your body has a built-in relaxation response? It does, and it’s linked to what’s called your parasympathetic nervous system (PNS). Often called the “rest and digest” system, the PNS works in tandem with your sympathetic nervous system (SNS), which controls the body’s “fight or flight” stress response. Both are part of your body’s greater autonomic nervous system. The SNS triggers the release of stress hormones, such as cortisol, which prepare you to handle a stressful situation. When the brain senses stress hormone levels are too high, the PNS is activated, your body relaxes, and you downshift to rest, relax, and recover from the stressful episode. However, when stress becomes a way of life, as it has for so many these days, the working relationship between the SNS and PNS can get disrupted. When that happens, the SNS remains activated and stress hormone levels stay elevated. This extreme stress can be destructive to both your body and brain. Thankfully, researchers have found that certain relaxation techniques can trigger the PNS, lower stress hormones, slow the heart rate, and promote relaxation. So, if you’re in a prolonged period of stress, you can practice the methods for relaxation below to help engage your PNS and turn off the stress response! 5 of the Best Natural Methods for Relaxation 1. Diaphragmatic Breathing Diaphragmatic breathing involves taking deep, rhythmic breaths. Research shows that reduced stress markers, less self-reported anxiousness, better cognition, and PNS activation may result from deep breathing. Here’s a simple exercise: Breathing with your diaphragm (or belly) rather than your chest: Inhale for a count of 3 to 4 seconds Pause for beat Exhale for a count of 6 to 8 seconds Pause for a beat Repeat this pattern 10 times The calming effects of deep breathing should be immediate! 2. Try Meditation Meditation is the perfect practice for activating the PNS and experiencing more calm in your mind, body, and emotions. By measuring heart rate, blood pressure, and stress hormone levels, studies have found that meditation can help activate the relaxation response and reduce stress and anxiousness. Both Transcendental Meditation and mindfulness meditation have been well-studied with positive results. Some forms of meditation allow for mind-wandering, and others are more disciplined about keeping the mind focused. They both have relaxation benefits. The best meditation is the one you’ll do on a regular basis. Explore what’s out there and be sure to make use of the many meditation apps available today. 3. Enjoy Nature It’s easy to overlook how profoundly restorative nature can be. One review looked at mental health markers, including reduction of anxiousness and stress, in college-aged individuals who spent 10 minutes sitting or walking in natural settings, contrasted with equal time in urban settings. Natural settings were shown to significantly and positively impact both psychological and physiological markers of well-being. If you can’t be in nature, you can listen to it for the relaxing effects. The sound of the wind in the trees, gentle waves on the beach, a burbling brook, or the song of birds can unlock your body’s relax response. Research shows playing natural sounds affected the bodily systems that control the fight or flight and rest and digest autonomic nervous systems, promoting more relaxation in the mind and body. 4. Practice Yoga, Tai Chi, or Qigong These three practices from ancient cultures all combine rhythmic breathing with a series of postures or flowing movements and are known to reduce stress. In terms of relaxation and calming the mind, performing the physical movements offers a mental focus that can help distract the mind from racing thoughts, while enhancing flexibility and balance. All of them have been shown to shift the body from the SNS to the PNS, and to help reduce feelings of anxiousness. 5. Progressive Muscle Relaxation Progressive muscle relaxation can be learned by nearly anyone, and it takes 10 to 20 minutes per day to practice. It’s done by deepening your breathing and bringing awareness to different parts of your body while you tense your muscle and then release it. It usually starts at your head, tensing muscles in your face and then releasing, and then working down the body – or starting with your toes and feet working your way up. Awareness is given to the changes that occur while tensing and releasing muscles. This technique has been shown to help reduce anxious feelings and promote sleep. Keep It Relaxed If these methods for relaxation don’t work for you, don't worry! There are others to explore, like petting your pet and using essential oils to create a relaxing environment at work or home. Also, consider promoting relaxation with nutritional support.* A quality supplement, like Calm My Brain, features ingredients scientifically proven to relax your mind and body.* Keep at it and you’ll learn how to cultivate a wellspring of inner calm. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about Calm My Brain and our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Calm My Brain: A Natural, Fast-Acting Way to Help Relieve Anxiousness
These days, it seems like everyone’s worried or on edge. Many people deal with stressful situations or anxious thoughts every day. Are you one of them? Stress and Anxiousness Stress is a response to an existing stress-causing factor (stressor). Anxiousness may be the result of intense, prolonged stress. These feelings may be disproportionate to the magnitude of the stressor and may continue well after the stressor is gone. Though stress and anxiousness are closely related, not all people who deal with excessive stress will experience feelings of anxiousness. However, anxiousness can be exacerbated by stress, which can be measured as elevated levels of the stress hormone cortisol. Managing stress often will also lessen feelings of anxiousness. Relieve Anxiousness Naturally Properly managing your stress is a critical factor in preventing the many mental and physical problems that can result from occasional, extreme anxiousness. Many people who struggle with anxious thoughts and feelings can end up predicting the worst, avoiding conflict, and being plagued with self-doubt, fear, and panic. Having heightened worry or feelings of anxiousness can lead to physical problems too, like muscle tension, dizziness, pain, shortness of breath, and panic attacks. If you’re one of the millions of Americans struggling with feelings of anxiousness, the good news is that diet and lifestyle factors, like taking high-quality supplements, can help. If you tend to worry or have persistent anxious thoughts, consider trying BrainMD’s new calm-promoting, stress-managing nutrient combination… Calm My Brain Calm My Brain provides generous daily doses of high-potency ingredients to manage stress, promote calm, and relieve anxiousness. You may benefit from this stress-managing formula if you have: problems with feelings of anxiousness trouble winding down at night challenges with food cravings difficulty coping with long-term stress poor sleep quality Benefits of Calm My Brain This product is a combination of three pure and potent ingredients that have been intensively researched for feelings of anxiousness, and with positive benefits for stress, relaxation, and sleep. The ingredients have been shown to help with: managing anxiousness and stress reducing tension and irritability regulating unhealthy eating supporting calmness improving sleep quality The clinically researched ingredients in Calm My Brain can make a substantial difference in improving the well-being of individuals living with feelings of anxiousness. Keep Calm and Live Well Researched in clinical trials, the ingredients in this robust formula may help lessen tension and irritability, enhance calm, relieve anxiousness and related unhealthy eating, and improve sleep quality. It also can help promote a balanced stress response, including cortisol levels. Calm My Brain is a unique blend of dynamic nutraceutical ingredients for reducing anxiousness, promoting relaxation, and preparing you for restorative sleep. Calm My Brain Ingredients The three high-quality ingredients in this formula work synergistically to relieve anxiousness. Magnesium (as threonate, bisglycinate chelate, malate, and citrate) Magnesium is an essential mineral for all the cells of the body and is fundamentally important for the electrical activity of the brain’s nerve cells and for the healthy functioning of their trillions of information connections (synapses). Known as “the relaxation mineral,” magnesium plays an important role in hydration, muscle relaxation, energy production, regulation of adrenaline and overall sleep quality. Magnesium promotes a calm, balanced, and mentally focused demeanor. Ashwagandha (standardized root extract KSM-66®) The ashwagandha herb (Withania somnifera) has long been revered for its medicinal powers in Indian Ayurveda and other traditional medicine systems in the Mediterranean, Africa, and China. As an adaptogen, it helps the body adjust to psychological or physical stress by promoting calm and overall mental focus. Ashwagandha has been associated with improved memory and attention, and also benefits feelings of anxiousness and sleep. L-theanine Extensive clinical research links this amino acid with the health benefits of green tea. L-theanine enhances relaxing alpha brain wave activity, reduces tension, and fosters a restful state without diminishing daytime alertness. It also can promote healthy blood pressure stability against the over-excitability associated with stress. Calm My Brain FAQ How can I take Calm My Brain? Adults can take 3 capsules daily, with food. Children ages 4-18 can take 1 capsule per 40 pounds body weight, maximum 3 capsules daily. Why does the label say this supplement is fast-acting? Clinical studies have found that l-theanine can bring on relaxation in less than an hour. Many supplements have magnesium oxide. Why don’t you use it? Magnesium oxide is known to be very poorly absorbed. BrainMD uses only the best ingredients available. This formula’s four magnesium sources are all well absorbed and well tolerated. Which other BrainMD supplements can make Calm My Brain work even better? Taking NeuroVite Plus and Omega-3 Power/Omega-3 Power Squeeze will help you be sure to get the core essential nutrients your brain and body needs to best utilize Calm My Brain. Is this product safe to take during pregnancy? With the safety of mother and baby in mind, we don’t recommend taking herbals while pregnant or breastfeeding. To ensure sufficient levels of magnesium during this period, Magnesium Chewables is a safe and effective option. Can this supplement make me dependent on it? No. As with other BrainMD products, this is a dietary supplement, not a drug, and is not habit-forming. I’m vegan and have allergies. Will I be able to tolerate this product? This product is suitable for vegans and compatible with keto or paleo dietary patterns. It is free from dairy, glutens, sugar, corn, soy, nuts, eggs, yeast, and artificial colorings or flavorings. Calm My Brain is a powerful combination of ultra-pure nutrients that offers comprehensive management of anxiousness and stress. Try it today! At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Here Are Some of the Best Health Benefits of Mushrooms
Mushrooms are a unique food that humans have been consuming for centuries. Some are delicious and healthy to eat, others can be mind-altering and potentially deadly. Health Benefits of Mushrooms Throughout history, certain mushrooms have been known as “Food of the Gods.” Today, we know that mushrooms contain the antioxidants glutathione and ergothioneine as well as other desirable substances thought to contribute to human health and well-being. Over the past several decades, mushroom consumption has been increasing in the U.S. This is likely due to the fact that mushrooms are a widely accepted ingredient in many different cuisines and they’re also desirable for their nutritional value. Edible mushrooms are low in calories, carbohydrates, fat, and sodium. They’re also cholesterol free. Additionally, they provide a lot of nutrients such as selenium, potassium, riboflavin, niacin, vitamin D, protein, and fiber. Their fiber types include glucans, known to be powerful immunity enhancers. Mushrooms are a healthy addition to any diet and can provide a variety of nutritional benefits. Mushrooms and Longevity A study came out this year that helps provide more evidence of just how beneficial mushrooms can be to our health. The study used data from the National Health and Nutrition Examination Survey from 1988-1994. In this study, over 15,000 participants beginning at an average age of 44 years were assessed for their mushroom intake and its relationship to dying from any cause during a study period of 19 years, on average. The researchers reported that those participants who consumed mushrooms had a lower risk of dying during this period. These researchers even concluded from this study, that replacing 1 serving of red or processed meat with 1 serving of mushrooms per day was associated with a lowered risk of death. They further reported that the higher the mushroom intake, the lower the risk of death. Mushrooms for Everyone If mushrooms can potentially help us live longer, healthier (and happier) lives, then maybe they really are an “elixir of life.” For those who like mushrooms, this is your cue to eat up! On the other hand, for those who don’t like to eat mushrooms, there’s some good news: you can find mushrooms in all shapes and forms these days. From teas and soups to supplements and powders, there’s something out there for everyone to enjoy the many health benefits of mushrooms. Smart Mushrooms Smart Mushrooms is firmly grounded in the most recent clinical and scientific research on medicinal mushrooms. It includes six mushrooms that have been revered for hundreds to thousands of years. All six are highly nutritious, and together they offer a broad spectrum of health benefits. Here’s a breakdown of the many powerful superfoods you’ll find in Smart Mushrooms: Lion’s Mane has shown promise in several clinical trials for improving cognition and mood, and its glucans also help boost immunity. Turkey Tail provides protein-bound glucan polysaccharides, intensively researched for their immune benefits. Cordyceps fights fatigue, supports immunity, helps counter stress, and benefits blood flow and oxygen utilization. Reishi’s immune and inflammatory response benefits help account for its 2,100-year popularity. Shiitake provides the glucan called lentinan, which improves immunity, and also has lung, liver, cardiovascular, and gastrointestinal benefits. Agaricus has a variety of glucans with immune benefits, and supports healthy blood sugar, cholesterol, and liver functions. Smart Mushrooms offers substantial promise for improving memory, mood, and other cognitive functions. Most of these mushrooms are proven tonic medicinals, offering a great variety of benefits for the brain and body. Smart Mushrooms can help increase energy, wellness, and high-level brain performance. It’s the Smart choice for immune and whole-body support. Try it today! At BrainMD, we’re dedicated to providing the highest purity nutrients to improve your physical health and overall well-being. For more information about Smart Mushrooms and our full list of brain healthy supplements, please visit us at BrainMD.
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Some of the Best Ways to Reduce the Stress Hormone Cortisol
Stress is prevalent in our society. A recent report from the American Psychological Association found that 84% of the people surveyed have been experiencing elevated levels of stress. Additionally, almost half of them reported mood issues, as well as weight changes and problems with sleep – conditions that often accompany being emotionally overwhelmed. Good Stress/Bad Stress Usually, people think of stress as bad…but stress is both good and bad. A little bit of stress is actually good because it can motivate you to meet your goals. Low level stress also can help you with resilience, problem solving, and adapting to everyday challenges. Stress becomes a problem when it’s intense, recurring, or remains unresolved over a sustained period. At that point, stress takes a toll and can become harmful to your health. If left unchecked, excessive stress can lead to serious personal and social consequences, including: Family conflict Low self-esteem Disability Withdrawal from social activities Alcohol and substance abuse Legal and criminal problems Anxiousness and other mental problems Suicide Fight or Flight The body’s “fight or flight” system is for dealing with threats – whether real or perceived. When we sense danger, our brain’s hypothalamus immediately sends an alert to our body. The brain then triggers the adrenal glands to release a surge of hormones, including adrenaline. Adrenaline increases your heart rate and blood pressure and provides a rush of energy to escape the danger. Another hormone involved in the fight or flight process is cortisol. What Is the Stress Hormone Cortisol? Cortisol is the body’s primary stress hormone. It acts like a biological alarm system, alerting your brain to potential danger. This natural alarm system communicates with the area of the brain that manages mood, motivation, and fear. Cortisol is produced by the adrenal glands – triangle-shaped organs that sit on top of the kidneys. The hypothalamus and pituitary gland help regulate the amount of cortisol in the blood. Cortisol receptors, found in the many of the body’s cells, use the hormone in many ways. For instance, if your body is placed on high alert, cortisol can temporarily shut down various bodily systems not needed in a fight or flight situation. These systems include the digestive, immune and reproductive systems. It also releases glucose to help repair damaged tissue. Once the danger is averted, cortisol levels gradually normalize and heartbeat, blood pressure, and other body systems should return to normal. However, if the body is subjected to consistent stress, its cortisol can remain at high levels. This can disrupt your body’s processes and create many health problems, such as: Brain problems Heart problems Headaches Mood issues Memory or concentration problems Weight gain Digestive issues Troubles sleeping Not only can excessive stress lead to physical health problems, it can also disrupt your mental health. So, what can you do if you’re dealing with too much stress? Here are some healthy strategies for reducing stress in your daily routine… 5 Natural Ways to Reduce the Stress Hormone Cortisol Deep Breathing Whenever you feel worried, frustrated, angry, or tense, do a deep breathing exercise. Focusing on your breathing for a few minutes is one of the simplest and quickest ways to settle your anxious or stressful thoughts. Breathe with your diaphragm rather than your chest. Try this exercise: Inhale 3 to 4 seconds Exhale 6 to 8 seconds Repeat this pattern 10 times When you slow down and become more efficient with your breathing, you may find that your problems aren’t as dire as you thought they were and that you’re feeling less stressed. Canine Companion Due to their natural ability to provide comfort, especially when you’re feeling stressed out, spending time with a dog can help your muscles relax, slow your breathing, and lower your heart rate. It also can help decrease levels of the stress hormone cortisol.. Overall, dogs can help you feel calmer. This effect is evident in the way trained service dogs can bring positivity to people who suffer with mood issues. Having a dog provides companionship, which is especially helpful for anyone who lives alone or is often isolated from others. Petting a dog can help alleviate feelings of loneliness by letting you know you aren’t alone. Spending time with your pet can help promote calmness by increasing levels of oxytocin and decreasing production of the stress hormone cortisol. Owning a pet that needs to be walked means you’ll get outside for fresh air and sunshine, which can lower your blood pressure, reduce your stress, and perhaps even help you lose weight. Meditation Scientific evidence shows that meditation can help calm anxiousness and stress and enhance brain function. A randomized controlled trial involving 93 subjects with mood issues was published in JAMA Internal Medicine. The researchers found that those in a stress-reduction program that incorporated meditation had a greater improvement in anxiousness and stress along with an increase in positive self-statements compared to those in a stress management group without meditation. Another group of researchers, who conducted a study with 40 college students, found that after only 5 days of meditation the participants had significantly lower levels of cortisol. Social Connections Never underestimate the importance of being around the right people. The health habits of the people you spend time with may have a dramatic impact on your own health and habits. So, surround yourself with people who are happy, upbeat, and kind. Building and maintaining healthy relationships may help you feel understood and cared for. When you care for others and feel cared for, your brain can release oxytocin, the “bonding” hormone, which can counteract some of the negative effects of stress. Nutritional Support Nutrients and herbals can help support your body’s resistance to stress. Everyday Stress Relief Everyday Stress Relief was specifically formulated to help replenish your brain and body’s nutrients that can be depleted by stress.* This supplement includes herbal extracts clinically proven to have calming and anti-stress effects, helping you to feel less anxious without making you sleepy.* It also helps with apprehension, tension, worry, and fatigue.* Here’s what you’ll find in this high-potency formula: Magnesium is a well-known calming mineral. It promotes a balanced and mentally focused demeanor.* The amino acid taurine supports the adrenal glands and is crucial for coping with stress.* The herb holy basil, revered both in Europe and the East, helps to improve adaptation to occasional anxiety and other problems related to stress.* A phytochemical derived from green tea, l-theanine helps to reduce tension.* Relora®, which is a unique mix of two herbs, may enhance healthy management of the stress hormone cortisol while easing tension, anger, negative mood, and confusion.* This safe, non-sedating, and non-habit-forming formula combines the multiple beneficial actions of these well-studied herbs and nutrients to help your brain and body cope with stress on multiple levels.* GABA Calming Support GABA Calming Support is a unique combination of clinically proven ingredients that can help you cope with restlessness, irritability, and other challenges associated with occasional feelings of anxiousness.* It can help facilitate the production of calming brain waves, correct stress-causing nutritional deficiencies, and promote relaxation.* This soothing formula includes: GABA – is the body’s main calming neurotransmitter. By slowing the excessive firing of neurons, it supports the body’s natural mechanisms for quieting the mind and gradually falling asleep.* L-Theanine – working mainly by way of GABA receptors on nerve cells, l-theanine is an amino acid that has calming and relaxing effects while preserving mental focus and also improves sleep quality.* Lemon balm (Melissa officinalis) – a member of the mint family that has been used as a medicinal herb for over 2000 years, lemon balm helps relieve stress and anxiousness, likely by increasing GABA activity in the brain as well as the activity of acetylcholine, a major neurotransmitter that promotes mental focus.* Magnesium – sometimes called the relaxation mineral, magnesium plays important roles in relaxing mind and body, calming racing thoughts, and promoting overall sleep quality.* Research suggests that magnesium’s calming effects are enhanced by vitamin B6.* Vitamin B6 – vitamin B6 is required by brain enzymes that produce the neurotransmitter serotonin, which promotes relaxation and positive mood.* This supplement provides B6 as pyridoxine and pyridoxal-5-phosphate, its most readily utilized forms.* GABA Calming Support boosts GABA to help relax your brainwaves and pump the brakes on anxious and fearful thoughts.* As a gentle, natural relaxation aid, it has helped countless people transition from an agitated awake state into a restful state that allows them to transition into sleep.* Stress Less These are just a few of the many practical and natural techniques that can keep your body’s production of the stress hormone cortisol in check.* Adopting these healthy tips can help reduce stress levels and increase your inner calm.* If you feel stressed and need a nutritional boost, give Everyday Stress Relief and GABA Calming Support a try today.* At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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ProBrainBiotics MAX Questions | What You Need to Know About Probiotics
Dr. Parris M. Kidd, our Chief Science Officer and Director of Quality, has a PhD in cellular and developmental biology from the University of California at Berkeley and 38 years of expertise in dietary supplements and integrative medicine. Today, we’re picking his brain on probiotics, getting the answers to your most pressing probiotic questions, and diving deep into the science behind our new broad-spectrum brain, immune, and gut probiotic supplement, ProBrainBiotics MAX. Read the full interview below. Probiotics Q&A with Scientist Dr. Parris Kidd Question 1: We know that our gut is intricately related to our health on many levels. We also know that most supplements require consistent daily intake for optimal results. Is this the case with probiotics, or can they be taken intermittently for occasional support and relief? “Probiotic supplements aren't likely to give immediate relief for intestinal problems. The live bacteria they supply have to settle in, reproduce and get to numbers that can become functionally significant in and amongst the trillions of other bacteria already in the gut. Probiotics are not drugs or even fast-acting nutrients. Think ecology – the human gut is a complex, intricate matrix of micro-ecosystems with bacteria as major players, and adjustments take time. It really takes well-designed clinical trials to inform us about the utility of any probiotic strain. In the case of BrainMD’s new broad-spectrum probiotic ProBrainBiotics MAX, the clinically documented benefits of the 7 strains – better brain, immune and gut health, better mood, better sleep, improved ability to cope with stress and anxiousness – are most likely to appear and expand over a period of weeks.” Question 2: Should you rotate your probiotic every 3-4 months for maximum benefit? “No. There’s no clinical evidence this is necessary or even helpful. With clinically-researched strains that are highly likely to improve overall microbiome functioning, as we've designed into this MAX product, the longer they're consumed the better the results likely will be. Don't believe everything you read on the internet.” Question 3: In the past, members of our team have shied away from taking probiotics due to adverse effects like bloating, gas, and intestinal discomfort after use. Will they be able to tolerate ProBrainBiotics MAX? “In my experience, the products most likely to have these undesired effects contain prebiotics – various forms of complex carbohydrates. It is not uncommon to experience gurgling or other intestinal discomfort after taking a probiotic + prebiotic product because the bacteria can go a bit crazy with all those carbs nearby. They can get very active and generate lots of gases, etc. ProBrainBiotics MAX doesn't have that problem because it doesn’t contain prebiotics.” Question 4: Speaking of prebiotics, is there any clinical research supporting their benefit? “Yes. But many so-called prebiotics aren't well researched in actual combination with probiotics. The prebiotic story is in theory pretty simple: good bacteria love to feed on fiber that the human gut cannot digest, and prebiotics are fibers of one type or another. The more fiber you consume, the better the environment for your probiotics. But prebiotics have to be very carefully chosen. Certain BMD products supply fiber that has proven prebiotic activity: the OMNI Protein products have 3 grams of fiber per serving, including 1 gram of inulin, which is an intensively researched prebiotic. Neuro Greens has 2 grams per serving of inulin and other prebiotic fiber, certified organic.” Question 5: What should you look for when choosing a probiotic supplement? “Clinical trial proof of benefit is so important for probiotic supplements. A probiotic strain can perform well in cultures, or in experimental animals, but the only way to know that it will consistently help people is to put it through clinical trials. As with any probiotic supplement – the good bacterial strains in PBB MAX face an uphill battle to produce health benefits. First, the tens of billions of good bacterial strains coming from our supplement each day are entering a gut milieu already populated by literally trillions of bad bacteria. Second, in the gut good bacteria are constantly being lost due to stress, toxins in foods, processed foods low in fiber and other nutrients, intake of alcohol or antibiotics or other drugs, and other negative factors. It’s a jungle down there – a micro-jungle, but jungle no less. This is why clinical trial proof of benefit is so important for probiotic supplements. Here are 4 things to look for: The Supplement Facts box must list them as strains, not just as species. For example, the species Lactobacillus helveticus has many different strains which have differing degrees of benefit. Lactobacillus helveticus strain Rosell®-52 has specific properties that make it beneficial, distinct from other strains of Lactobacillus helveticus. The strains that are used must have clinical research to support the benefits claimed for them. All 7 of the strains in BrainMD's probiotic products have shown specific benefits in clinical trials. The bacterial counts (CFUs, Colony-Forming Units) must be sufficient to cover the counts that worked in clinical trials. The benefits claimed for a probiotic product must be based on scientific research, most preferably on the expert consensus of results from human clinical trials that are randomized, double-blinded and placebo-controlled.” Question 6: BrainMD has two clinically researched probiotic supplements ProBrainBiotics and ProBrainBiotics MAX. Can you explain the difference between them? “ProBrainBiotics is a powerful probiotic supplement and a pioneering brain product for its time. With two clinically validated bacterial strains (Lactobacillus helveticus Strain Rosell®-52 and Bifidobacterium longum Strain Rosell®-175), ProBrainBiotics delivers psychobiotic support for coping with everyday stress and can especially benefit those with mood issues. ProBrainBiotics MAX is the next generation of ProBrainBiotics. With seven clinically validated bacterial strains (including both strains found in ProBrainBiotics), the total amount of clinical research support for the brain, gut and immune benefits of ProBrainBiotics MAX exceeds any other probiotic on the market. It goes beyond the brain.” Question 7: What does the research say about the long-term use of probiotics? Should we do a course every 3 months, every day, once a year? “While working on this project I became convinced that as a form of "nutritional health insurance" it's best to take a clinically verified probiotic supplement every day, along with a really good multiple vitamin-mineral and a clean, omega-3 concentrated fish oil.” Question 8: Is it also important to take digestive enzymes in addition to a probiotic? “Older people especially can benefit from digestive enzymes, and so can younger people who have damage to organs that make digestive enzymes, such as the pancreas. Plant enzymes are heavily promoted, but some of them are not potent enough to work well. Freeze-dried pancreas glandular preparations from pigs or sheep can be more potent digestive enzyme sources, given they are sourced from disease-free herds.” Question 9: Why do some probiotics require refrigeration while others do not? Does ProBrainBiotics MAX require refrigeration? “Probiotics are live bacteria, by definition. As time passes, some of them die. They're also sensitive to exposure to air, as occurs when the bottle is opened. Refrigeration slows these damage processes but can't stop them. ProBrainBiotics MAX doesn't require refrigeration – it contains extra bacterial cells to allow for loss over time when stored at room temperature. We also sealed the capsules individually in blister packs, to protect them from damage due to ongoing exposure to air.” Question 10: We loved your comprehensive explanation of the microbiome and what throws it off balance. (Tune in here if you missed it!) Can you expand on how toxins affect the microbiome? “Anything toxic getting into your mouth then getting swallowed can eventually come into close contact with your gut bacteria and damage or destroy some of them. Toxins entering the lungs can damage the delicate lung tissue and produce secondary toxins, which then enter the bloodstream and travel to the gut. It's very important to understand that every organ of the body is connected with every other organ (mainly by the circulation), so toxins generated anywhere in the body can travel to the gut and also hurt the microbiome. Think of your body as having a TOTAL TOXIC LOAD. Even creams and other stuff applied to the skin can become absorbed into the blood vessels under the skin and increase the toxic load. For optimal health – of your microbiome, and the rest of your body – you'll need to keep your total exposure to toxins to a bare minimum.” Question 11: Does antibacterial soap and hand sanitizer have adverse effects on the microbiome? “On the skin microbiome, probably yes. Many experts think antibacterial soap is not a good idea – they don't work, and they typically contain toxic chemicals like triclosan. Neither the soap nor the hand sanitizer should directly impact the gut microbiome. But it's possible that if you applied a lot of the sanitizer to your skin multiple times during the course of each day, some of it could get absorbed into your skin circulation and find its way to your gut.” BrainMD: Thank you, Dr. Kidd. We’ll stick to washing our hands with regular soap and water for 20 seconds as recommended by the CDC. Is there a question we haven’t answered? Please share it in the comments! For more information regarding gut health and the intricacies of the gut microbiome, tune into our free 60-minute webinar here.
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Here’s How to Flavor Your Foods with Brain-Smart Herbs and Spices
It’s easy to forget that herbs and spices aren’t just flavor enhancers for food, but promoters of good health too. These plant-derived seasonings have a long history of medicinal applications that you can use in your cooking. Here are some of the most powerful, brain-smart herbs and spices, along with a few of their benefits. Flavor Your Foods with These Brain-Smart Herbs and Spices! Brain-Smart Herbs Basil This herb is loaded with potent antioxidants that can improve blood flow to the brain, which is essential for good cognitive function. Garlic This bulbous herb has a particularly unique array of sulfur antioxidants. Eating garlic promotes healthy blood flow and overall brain function. Regular consumption of garlic can help boost the immune system’s ability to ward off colds and flus. Garlic also can help keep blood sugar manageable along with cholesterol levels. Marjoram The lineup of nutrients in this sweet-flavored herb is impressive – vitamin C, vitamin A, as well as the vitamin-like nutrients lutein and zeaxanthin, which are essential for vision and may also be important for a healthy brain. Marjoram also has anti-inflammatory and anti-bacterial properties. Mint The scent of peppermint can help improve memory and focus, and its oil can soothe digestive issues. Recent clinical research reported that certain substances in peppermint enhanced cognition. Oregano A potent antioxidant herb, oregano helps protect brain and body cells from free radicals that can cause premature aging. It may also ease migraine headaches. Rosemary Rosemary is a well-known herb that has both antioxidant and anti-inflammatory properties. It promotes healthy circulation and digestion, and helps protect the brain’s cognitive functions. Saffron This herb has been extensively researched and found to help boost mood and alleviate occasional anxiousness. Recent clinical research suggests saffron may also help improve memory and learning. Sage Sage contains substances that inhibit an enzyme which breaks down acetylcholine, a neurotransmitter that helps improve memory. In this way sage can help the aging brain and body conserve acetylcholine nerve pathways, which are crucial for numerous bodily functions. Thyme This herb is densely packed with polyphenols, vitamins, and minerals which contribute to brain health. Brain-Smart Spices Black Pepper This spice enhances absorption of cognitive-supporting compounds such as curcumin (a group of 3 powerful antioxidants). It also may aid with digestion. Cayenne Pepper The bold taste in cayenne is created by capsaicin, a well-known pain reliever. Capsaicin supports healthy blood flow to tissues by stimulating the release of nitric oxide, which helps your blood vessels expand. This allows for greater blood flow and increased energy in the brain and body. Cayenne pepper may also stimulate metabolism, but too much of it may elevate blood pressure. Be sure to moderate your intake if you suffer from hypertension. Cinnamon This sweet/savory spice has been in use for over 4000 years. It supports healthy management of cholesterol, triglycerides, and blood glucose. Cinnamon provides a treasure trove of health benefits including anti-inflammatory and antimicrobial properties, modulating effects on cholesterol levels, and promoting healthy blood flow and blood pressure. Cloves This fragrant super-antioxidant spice has had many medicinal roles over the centuries, from soothing upset stomach and tooth pain (clove oil) to relieving diarrhea and acting as an expectorant. It also contains eugenol, a potent anti-inflammatory. Cloves can help support healthy blood flow, which is crucial for the healthy function of the brain and body. Coriander The phytonutrients in coriander may help control blood sugar and lower cholesterol levels. It’s rich in manganese, vitamin C, and vitamin K. Curcumin Deriving from the turmeric root, curcumin is a mixture of 3 gold colored polyphenol substances that are used in curries. Curcumin has been extensively researched for its powerful antioxidant and anti-inflammatory effects. It also helps promote working memory, calmness, and satisfaction in coping with mental strain. Curcumin concentrates are proven to be well absorbed and have been found beneficial for mood, circulatory, vision, joint, liver, skin and prostate health. Nutmeg This aromatic spice gives foods a delightful flavor. Traditionally, it’s been used for occasional anxiousness, against diarrhea, and for antibacterial control especially in tooth decay. NOTE: Avoid use of higher amounts of nutmeg (120 milligrams or more). Spice Up Your Life These are just some of the many brain-smart herbs and spices that can support your brain and body health. To boost your mood, memory, and overall mental clarity, start adding these herbs and spices to your diet. For some of these herbs and spices, more doesn’t necessarily mean better. For instance, using too much nutmeg, black pepper, cayenne, and garlic can cause stomach discomfort. You can introduce them one at a time or pick up all of them during your next visit to the grocery store. Try them out and feel free to share your “spiced up” recipes with your friends and family. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Here Are Some of the Best Benefits of Vitamin B12?
In our fast-paced society, where convenience has driven many to eat on the go, skip meals, munch on sugary snacks, purchase processed foods that are low in vitamins and other essential nutrients, and consume foods that have been chemically treated, it’s becoming more and more difficult to maintain a balanced and healthy diet. Due to this gap in nutrition, most people could use a little help from dietary supplements to ensure they’re getting all the nutrients needed for optimal health. This is especially true of the B vitamin family, which is made up of 8 vitamins. All our cells need the 8 B vitamins to function at their best. Although they’re commonly recognized as a group, each of the B vitamins is required by a unique set of the body’s enzymes to perform unique and important functions. Deficiencies in any of these can lead to serious health problems. Let’s take a closer look at vitamin B12… Vitamin B12 Essentials This B vitamin, also known as cobalamin, is a team player. It works with a set of enzymes that use folate to generate and utilize methyl groups that have a huge impact on our health. Though a small chemical group (one carbon atom with three hydrogens attached), methyl is needed by all our cells to make their DNA, repair DNA that becomes damaged, make and regulate DNA and the RNA involved in protein production and regulation, and facilitate the growth and proliferation of all our approximately 30 trillion cells. The methyl form of vitamin B12 is used as a backup for the methyl groups provided by methylfolate. Substantial dietary intakes of B12 are required for the bone marrow to make red blood cells, which carry oxygen, and the variety of white blood cells that are crucial to our immune defenses. Growing children, pregnant women, and the elderly all tend to have an increased nutritional need for B12. There’s a consensus among experts that for these populations, supplementing with vitamin B12 is a good idea. Most of the multiples and other dietary supplements that provide B12 offer it in a form that is potentially harmful and requires more of our energy to process. The most commonly used B12 dietary ingredient is cyano-cobalamin, B12 with a cyanide group attached. The body has to expend precious energy to remove the cyanide group, then convert the B12 to methyl-B12 or other forms before they can use it. Smokers and women who use certain birth control hormone mixes are especially at risk of damage from cyano-B12. BrainMD provides B12 as methyl B12 because it’s safe to take, needs less energy to utilize, and is the most effective B12 ingredient available. In our products, we also team methyl-B1 with folate as methyl-folate, which works better than the artificial substance known as folic acid. Vitamin B12 is crucial for the brain and all the body’s other nervous tissues. Beyond needing B12 for their usual housekeeping functions, our nerve cells need it to assist in producing such key neurotransmitters as dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline). The brain also needs B12 to make melatonin, the main hormone that ensures we can get to sleep and stay asleep. Vitamin B12 is essential for the structural integrity of the brain and spinal cord. Higher levels of B12 are linked to better memory, mood, behavior, personality and mental clarity. Vitamin B12 for Memory and Mood The availability of methyl groups is fundamental to every aspect of the brain’s functioning, from its management of our basic physiological functions, such as sleep, to its higher responsibilities of managing memory, mood, judgment, behavior, and personality. The brain must have ample supplies of methyl-B12 along with ample methylfolate, to ensure it can generate sufficient energy, maintain healthy neurotransmitter balance, and carry out hundreds of other enzyme reactions. B12 deficiency can mimic severe memory impairment. Vitamin B12 in Foods Vitamin B12 is predominantly found in various meats, such as chicken, beef, fish, pork, and clams. Since it doesn’t naturally occur in plant foods, vegans and vegetarians may have low levels of vitamin B12. Those who don’t get enough in their diet may need to take a B12 supplement. However, the absorption of B12 is complicated and requires a very healthy gastrointestinal (GI) tract, and even meat-eaters can be deficient in B12. Vitamin B12 Deficiency The array of proteins along the GI tract that enable the absorption of vitamin B12 can be damaged by over-the-counter “digestive aids” such as antacids, histamine type 2 receptor blockers, and proton pump inhibitors. Certain antibiotics, anticonvulsants, and metformin also can deplete B12. Growing children, vegans, vegetarians, pregnant women, the elderly, smokers, and others taking various medications, all are at risk of vitamin B12 deficiency. Quality Vitamin B12 BrainMD closely follows clinical and scientific research on vitamins and other nutrients. With vitamin B12, the research clearly proves that methyl-vitamin B12 is the best ingredient to use in supplements.* We spare no expense in providing a sufficient allowance of methyl-B12 in our supplements to enable its efficient absorption by mouth.* By teaming it with methylfolate, we ensure our customers have access to adequate supplies of methyl, that small chemical group so incredibly important for the health of our brain and entire body.* At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.
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Benefits of Turmeric for Your Brain & Must-Try Recipes!
In today’s stressful world, we can get remarkable help from the food we eat that can make a positive impact on our body's health. At BrainMD, we offer supplements with breakthrough ingredients for improving brain health while also promoting a sharper memory. In this blog series, we’re taking a closer look at our ingredients’ origins, uses, and recipes, so you can incorporate them into your diet. What is Turmeric? Turmeric is a popular ingredient that’s been used for thousands of years as a spice, medicinal herb, and even for spiritual support. Traditional Asian societies used it for practically all their medicinal needs. Hundreds of millions of people in other countries include turmeric in their daily diet, and it’s recommended that we do the same. Turmeric is a tropical plant and a member of the ginger family. The turmeric root sold at food markets is an underground stem or rhizome. From the outside, turmeric looks a lot like ginger, but when you break them in half, turmeric’s interior is gold, while ginger’s is green. Turmeric originates from India and has been used as a spice in dishes for thousands of years. The turmeric root is dried, ground into powder, and added as a major constituent of yellow curry sauces. Due to its long and cosmopolitan history as a spice, turmeric is found in many different foods. But turmeric powder can only deliver limited amounts of curcumin in a meal. After the three active curcumin substances were discovered a few decades ago, scientists focused on exploring how they worked in the body and used modern techniques to confirm their surprisingly broad range of health applications, including turmeric for your brain and memory. What is Curcumin? Curcumin is an abbreviated name for a combination of the three main ingredients of turmeric known to improve health: polyphenol curcuminoids called curcumin, demethoxy-curcumin and bis-demethoxycurcumin. Polyphenols occur in many plants and are adequate antioxidants, but these curcuminoids are exceptionally powerful and have a diverse range of cell-level molecular actions. Curcuminoids have sparked intensive clinical investigation for applications to practically all aspects of human health. In addition to supporting the brain, curcumin has benefited the eyes, heart and circulation, joints, intestinal tract, skin, prostate, muscles, nerves, and numerous other human tissues. The key to getting the maximum benefit from curcumin is to ensure that it is adequately absorbed once you take the supplement. Benefits of Longvida Curcumin for Your Brain & Memory The only factor that limits curcumin’s health-giving potential is that all three of the active substances are poorly absorbed in the body. That’s why BrainMD uses Longvida® Optimized Curcumin Extract in our Brain Curcumins supplement to ensure your body will make the most of this powerful ingredient. Longvida curcumin is a sophisticated curcumin concentrate formulated for ultrahigh absorption and is known to improve human brain function. Since many curcumin supplements are not supported by adequate human research, we chose the Longvida curcumin ingredient for our Brain Curcumins because it is backed by competent clinical trial investigation. BrainMD’s scientific-medical team developed Brain Curcumins using a specially concentrated extract of all three curcumin substances from turmeric as the main ingredient. This Longvida curcumin ingredient was developed at UCLA to add incredible antioxidant power to your cells. It also regulates the inflammatory response and generally helps counter everyday stressful, emotional, chemical, and physical challenges. A double-blind clinical trial found that it helps maintain a healthy mood and cognitive functioning in people under mental strain. The clinical trial also established that this specific curcumin ingredient can help us keep a positive mood when under stress, stay alert and calm while under mental strain, and reduce the fatigue we can develop after a mentally challenging task. Some of the subjects who received Longvida curcumin in this trial showed better working memory (such as multitasking) just 1 hour after taking it. In this trial, cholesterol measures also improved. In another trial, this ingredient was found to have powerful circulation benefits. Since the chemical composition of every curcumin ingredient is so specific, it isn’t appropriate to transfer results from clinical trials with one ingredient to make conclusions about another ingredient. That’s why the BrainMD team waited until the necessary brain-focused clinical trial was completed and published, before developing our Brain Curcumins supplement. The Curcumin and Cumin Confusion While these two ingredients may sound similar and are even included together in many recipes, they are completely different. Curcumin is derived from turmeric in the ginger family while cumin is related to the parsley family. 2 Simple Turmeric Recipes to Try Turmeric is easy to incorporate into a healthy diet. Add a pinch of turmeric powder to your favorite dishes, from scrambled eggs to roasted vegetables, and try our recipes for Smooth Sweet Potato Soup and Cauliflower Garlic Mashed Potatoes: Smooth Sweet Potato Soup 1/2 cup Onion, Diced 1/3 cup Celery, Diced 3 Tbsp Leeks, Diced 2 Cloves of Garlic, Minced 6-7 cups Low Sodium Vegetable Stock 1 1/2 lbs. Sweet Potatoes, Peeled and Diced 1 stick Cinnamon 1/4 tsp Nutmeg 1 tsp Real Salt (Optional) 1 tsp White Pepper 1/2 cup Almond Milk or Coconut Milk 2 Tbsp Fresh Sage, Finely Chopped 1/4 cup Sunflower Seeds (Optional) 1/8 cup Cranberries, for Garnish (Optional) 1 Pinch of Cinnamon, for Garnish 1/2 Teaspoon of Turmeric Powder Cauliflower Garlic Mashed Potatoes 1 head Cauliflower 2 cups Vegetable Broth or Water 1/4 cup Soy Milk or Unsweetened Almond Milk 1 Tbsp Earth Balance Spread 1/2 tsp Italian Seasoning 2 Cloves of Garlic, Minced 1 tsp Fresh Rosemary, Finely Chopped 2 tsp Cornstarch (mixed with 2 tablespoon water) Real Salt and Pepper, to Taste 2 Tbsp Finely Chopped Chives (Optional) 2 cups Spinach 1/4 cup Sunflower Seeds, Raw 1/2 Teaspoon of Turmeric Powder Remember, you can take an effective daily dose of curcumin in the supplement Brain Curcumins. You might also want to try Serotonin Mood Support to give you an added boost in mood throughout the day. As the leader in brain-directed supplements, BrainMD offers the highest purity ingredients in our memory products. For more information about Brain Curcumins or our full catalog of brain healthy supplements, visit the online store at BrainMD.
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BrainMD: 10 Years as the Leader in Brain-healthy Supplements
As we celebrate our 10th Anniversary, we want to take this opportunity to thank YOU for supporting our company over the years. Without you, there would be no BrainMD. Now that we’ve reached the decade mark, we want to pause and reflect on our history, our unique positioning in the supplement industry and why we do what we do. Our Why At BrainMD, we realize the last thing the world needs is another line of high-priced, cheaply-made supplements. From the start, we’ve committed ourselves to providing ultra-pure, clinical-grade, ethically sourced dietary supplements that can supply you with the nutrients you need to lead a brain-healthy life. We believe in a whole person approach to physical and mental wellness. We’ve dedicated ourselves to helping people feel better by creating the highest quality, brain-healthy supplements and nutritional products on the market. The integrity of our work, and our belief in the importance of helping people, inspires our commitment to excellence. Solid Foundation One of the things that makes BrainMD unique is that we’re backed by the combined knowledge, clinical experience and guidance of a MD and a PhD. Our Founder: Daniel G. Amen, MD Dr. Amen is a double board-certified psychiatrist, clinical neuroscientist, brain-imaging specialist, and multiple New York Times bestselling author. He is the visionary behind Amen Clinics, Amen University, and the numerous products and services offered by BrainMD. Our Chief Science Officer: Parris M. Kidd, PhD Dr. Kidd earned his PhD at the University of California at Berkeley and has been active in integrative medicine for over 35 years. He has focused on the brain for over 25 years and has pioneered awareness of phosphatidylserine (PS), omega-3s and numerous other ingredients. Backed by Science Would it surprise you to know that many of the supplements in the marketplace today have little or no backing from human clinical studies? Our clinical research team incorporates the latest scientific findings into creating a wide array of specialized formulas that promote optimal brain function and brain-body integration. We want you to be as fully informed as possible. That’s why we’re committed to providing you with educational resources on the clinical research behind our products and the science that supports our choice of ingredients that comprise our superior grade nutritional formulas. Our supplements are formulated with exacting standards and are developed from numerous clinical trials and other studies published in peer-reviewed scientific journals. Brain Directed We recognize that the health of your brain¹ is central to your overall success. Feeding your brain properly is essential for optimal fitness and can be the first line of defense in preserving your mental and physical well-being.² With the use of brain SPECT imaging, Dr. Amen discovered that some prescription medications can damage the brain. He sought out non-toxic solutions for his patients and developed dietary supplement formulas targeted to memory, mood, focus, and other specific brain functions. Those early formulas were so effective, they eventually led to the creation of the first supplement company solely dedicated to brain health, BrainMD. Rigorously Tested Our products are developed to promote brain-healthy living, and their ingredients, combinations, and dosages are always grounded in science. During the formulation process, our product development team may be required to review hundreds of clinical trials and other scientific studies to make sure we’re aware of all the research relevant to the product. We work tirelessly to ensure that the ingredients (and the levels of each ingredient) in our products are shown to be both effective and safe. When it comes to ingredients, we know which ones to include in our products and which ones to leave out. We have stringent standards for selecting the raw materials for our products and work hard to verify that our ingredients are free of heavy metals, pesticides, solvents, bacteria, mold, glutens, sugar, egg, dairy, and any other unnecessary additives. Our ingredients undergo extensive testing to establish their identity, purity, and potency. We partner with the highest-quality manufacturers, which conform to the current Good Manufacturing Practices (cGMP) as required by the U.S. Food and Drug Administration (FDA). We use independent labs to further verify the manufacturer’s quality test results. You can be confident that with each serving you take of any of our products, you’re getting the nutrients promised on the label. Array of Products Over the last 10 years, we’ve developed products essential for everyone’s nutritional needs: our premium multivitamin, NeuroVite Plus Multivitamin, ultra-concentrated EPA and DHA fish oil, Omega-3 Power, and high-purity Vitamin D3 5000. Our line of 30 supplement products was developed to support a wide range of individual needs, including: [wc_box color="inverse" text_align="left" margin_top="" margin_bottom="" class=""] Brain support (supplement systems Brain & Body Power, Brain & Body Power MAX) Memory (Bright Minds Memory Multivitamin, Brain & Memory Power Boost, NeuroPS) Mood (Serotonin Mood Support, SAMe) Focus (Focus & Energy, Attention Support) Relaxation and stress (GABA Calming Support, Everyday Stress Relief) Sleep (Restful Sleep, Magnesium Chewables) Brain neurotransmitter balancing (NeuroLink, Tyrosine) Gut-brain health (ProBrainBiotics) Prenatal (Smart Prenatal) Children (Kids’ NeuroVite, Coromega Omega-3 Squeeze) Drink mix (Brain Boost On-the-Go) Plant-based protein powder (OMNI Protein – Vanilla and Chocolate) [/wc_box] BrainMD = Brain-healthy Supplements This extraordinary group of products is the only line of dietary supplements available today that is specifically developed to address the full spectrum of brain health concerns. As BrainMD moves into its second decade, we look forward to continuing to serve you while developing new products to help you enjoy all the benefits of a brain-healthy life. At BrainMD, we’re dedicated to providing the highest quality supplements to improve your physical health and overall well-being. For more information about our full list of brain healthy supplements, please visit us at BrainMD. *These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen. References: 1. Gorelick, P. B., & Sorond, F. A. (2023). What is brain health? Cerebral Circulation - Cognition and Behavior, 6, 100190. https://doi.org/10.1016/j.cccb.2023.100190 2. Firth, J., Teasdale, S. B., Allott, K., Siskind, D., Marx, W., Cotter, J., Veronese, N., Schuch, F., Smith, L., Solmi, M., Carvalho, A. F., Vancampfort, D., Berk, M., Stubbs, B., & Sarris, J. (2019). The efficacy and safety of nutrient supplements in the treatment of mental disorders: A meta‐review of meta‐analyses of randomized controlled trials. World Psychiatry, 18(3), 308–324. https://doi.org/10.1002/wps.20672
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How Can Ginkgo Biloba Promote a Better Memory?
Ginkgo biloba is the most ancient living tree. It has been around for at least 200 million years and is often referred to as a living fossil. This tree is extremely hardy, resistant to pests, can reach 100 feet in height and can live for over a century. Ginkgo has been used in traditional medicine for thousands of years. Standardized extracts prepared from the leaf have existed for over 50 years and are used worldwide for a diverse range of health benefits. The ginkgo biloba extract is prepared from the leaves and standardized to two sets of beneficial substances: powerfully antioxidant flavone glycosides (22-27%, including quercetin, kaempferol, isorhamnetin, isoquercetin and rutin); and terpene trilactones (5-7%, including several ginkgolides along with bilobalide). A competently prepared ginkgo biloba extract also is free of ginkgolic acid, a known toxin. The exceptional health benefits of ginkgo biloba extract are linked to synergy: the individual constituents multiplying each others' benefits. The flavone glycosides improve the body's antioxidant defenses while lowering free radical and other potentially toxic activity. The terpene trilactones promote healthy inflammation control and enhance cell replacement in the brain and other organs. Both sets of constituents have numerous other beneficial actions. Standardized ginkgo biloba supplements have been successfully used for decades. The sections that follow review their best-documented benefits for brain and body. One recurring theme is improvement of blood flow. Top Benefits of Ginkgo Biloba for Brain & Body Ginkgo Biloba for Memory and Other Brain Functions In clinical trials, ginkgo biloba supplements have improved working and long-term memory in both young and old, healthy adults. In some trials it also improved speed of information processing and word and face recognition. These benefits are consistent with its improvement of brain blood flow, to deliver oxygen and all the other nutrients the brain needs for generating a minimum 20% of the body's total energy. SPECT scanning (Single Photon Emission Computed Tomography) is a powerful and precise tool for imaging blood flow in the brain. In a 2003 double-blind trial, healthy volunteers aged 60-70 years received either ginkgo biloba extract (80 mg) or a placebo daily for 8 months. SPECT documented improved blood flow in both brain hemispheres for the ginkgo group, statistically better than the placebo group. This trial included a number of cognition tests, most of which documented superior results from the ginkgo biloba extract over the placebo. The ginkgo group improved more than the placebo group in information processing speed, attention, "visuospatial" tests (tracking and manually arranging blocks into patterns), and "general intelligence" (including vocabulary and comprehension). Ginkgo biloba supplements also can reduce anxiousness better than placebo, even in subjects of advanced age with cognitive challenges. Unlike some other options for anxiousness, ginkgo biloba extract is very well tolerated, doesn't cause dependence or impair mental sharpness, and so can be used by the young or elderly while driving, going about their other daily activities or even while at work. Ginkgo Biloba Benefits for The Heart and Circulation Besides increasing the brain's blood flow, ginkgo biloba supplements can increase blood flow elsewhere in the body. Their awesome antioxidant array protects blood vessel walls and positively influences their capacity to dilate or contract as needed. The multiple active substances in the extract operate via support for healthy inflammation control, regulation of tissue messenger substances, and numerous other possible actions. Ginkgo biloba supplements are known to improve blood flow to the heart. Heart surgery typically causes "free radical" damage to the heart muscle. In a French trial, men and women received either a ginkgo supplement (360 mg) or a placebo daily for 5 days leading up to their aortic valve replacement surgery. The ginkgo group released less free radical and other damage products from their hearts than did the placebo group. Ginkgo Biloba Benefits for the Eye and Vision Healthy volunteers of average age 34 years who took a ginkgo biloba supplement taken at 120 mg daily showed improved blood flow to their eyes after just 2 days, compared to a placebo. Ginkgo also can protect and enhance functioning of the retina, the eye's sensing tissue that is constantly vulnerable to damage from intense light exposure. Ginkgo Biloba Benefits for the Ear and Hearing We need our ears to hear, of course. But literally overnight, a person can suddenly lose their hearing in one ear. Often hearing returns on its own, but sometimes it doesn't. European physicians found that giving ginkgo biloba extract (240 mg daily) increased the chances for complete hearing recovery after one week. There were cases in which hearing returned at a better level in the affected ear and even also in the other ear. The middle ear is very important for managing balance, and difficulties with this tissue can cause dizziness and vertigo. Double-blind trials found ginkgo effective for these problems, compared to placebo. It may also help relieve ringing or buzzing of the ears (tinnitus) in some individuals. Ginkgo Biloba Benefits for Women A large percentage of women of reproductive age experience a range of discomforts for days leading up to and following their menstrual period. Taking ginkgo biloba supplements has produced substantial relief of breast tenderness and other of these discomforts, when started during the 16th day of the menstrual cycle and continued until the 5th day of the following cycle, for at least one or two cycles. Ginkgo Biloba for Kids Ginkgo biloba supplements have shown some promise for children with attention and behavior challenges, in two double-blind trials. In the first trial, children received either ginkgo biloba extract at 80 to 120 mg daily, or methylphenidate (MPH) at 20 to 30 mg daily, for 6 weeks. Ginkgo worked less well than MPH but had fewer adverse effects. In the second double-blind trial, children and adolescents received either MPH (20 to 30 mg daily) + ginkgo (80 to 120 mg daily) or MPH + a placebo, for 6 weeks. The MPH + ginkgo group came out better on both the parent and teacher attention ratings, and those receiving ginkgo had a far higher positive response rate. A subsequent "open" trial (conducted without a placebo) tried ginkgo at a higher dose (up to 240 mg daily). Twenty children aged 6-13 years safely tolerated the ginkgo biloba extract for 5 weeks. The parents rated attention and "prosocial behavior" as improved, and the researchers rated hyperactivity and impulsivity as improved. The children's self-reported quality of life did not change. Ginkgo also showed promise for children with dyslexia-type problems in another open trial. Ginkgo biloba supplements certainly deserve further exploration via larger, well-controlled clinical trials for children with attention, learning, or behavior problems. The Safety of Ginkgo Biloba Extract When competently prepared and standardized, ginkgo biloba supplements are very well tolerated, with less than 2 of every 100 consumers reporting gastrointestinal discomfort. It is safe to take long-term: clinical trials have lasted for as long as 6 years. Non-standardized ginkgo leaf or seeds are likely unsafe due to high content of the toxin ginkgolic acid. Ginkgo supplements are not recommended for women who are pregnant or lactating, due to lack of sufficient data. Ginkgo Biloba Interactions The main concern here is possible negative interactions between ginkgo and anticoagulant drugs. There is evidence for and against such harmful interactions: though several large-scale clinical trials found no bleeding risk, there is other evidence to the contrary. From an abundance of caution, BrainMD recommends against combining Ginkgo use with warfarin or other anticoagulant drugs. Closing Remarks Ginkgo biloba has been a medicinal treasure for thousands of years, and a dietary supplement herbal ingredient for over half a century. BrainMD employs it mainly to enhance blood flow, and it does this so well it very likely improves the delivery – and therefore the benefits – of the nutrients that we mix with it. For its incredibly diverse benefits, its safety, and its added value for delivering other dietary supplement ingredients, ginkgo biloba extract is in a class of its own. Key Scientific References Napolitano JG, others. Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba. Magnetic Resonance Chemistry 50 (8):569-575 (2012). Pietri S, others. Ginkgo biloba extract (EGb 761) pretreatment limits free radical-induced oxidative stress in patients undergoing coronary bypass surgery. Cardiovascular Drugs and Therapy 11:121-131 (1997). Silberstein RB, others. Examining brain-cognition effects of Ginkgo biloba extract: brain activation in the left temporal and left prefrontal cortex in an object working memory task. Evidence-Based Complementary and Alternative Medicine 2011:Article ID 164139, 10 pages (2011). Stough C, others. Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. International Journal of Neuropsychopharmacology 4:131-134 (2001). Wu Y, others. Ginkgo biloba extract improves coronary blood flow in healthy elderly adults: role of endothelium-dependent vasodilation. Phytomedicine 15 (3):164-169 (2008). Santos RF, others. Cognitive performance, SPECT, and blood viscosity in elderly non-demented people using Ginkgo biloba. Pharmacopsychiatry 36:127-133 (2003). Singh SK, others. Ginkgo biloba as an alternative medicine in the treatment of anxiety in dementia and other psychiatric disorders. Current Drug Metabolism 18 (2):112-119 (2017) Gavrilova SI, others. Efficacy and safety of Ginkgo biloba extract EGb 761® in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial. International Journal of Geriatric Psychiatry 29:1087-1095 (2014). Spiegel R, others. Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia: a meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials. Clinical Interventions in Aging 13:1121-1127 (2018). Donfrancesco R, Ferrante L. Ginkg biloba in dyslexia: a pilot study. Phytomedicine 14:367-370 (2007). Chung HS, others. Ginkgo biloba extract increases ocular blood flow velocity. Journal of Ocular Pharmacology and Therapeutics 15 (3):233-240 (1999). Burschka MA, others. Effect of treatment with Ginkgo biloba extract EGb 761 (oral) on unilateral idiopathic sudden hearing loss in a prospective randomized double-blind study of 106 outpatients. European Archives of Otorhinolaryngology 258 (5):213-219 (2001). Sokolova L, others. Treatment of vertigo: a randomized, double-blind trial comparing efficacy and safety of Ginkgo biloba EGb 761 and betahistine. International Journal of Otolaryngology 2014: Article ID 682439, 6 pages, https://dx.doi.org/10.1155/2014/682439 (2014). Hudson T. Ginkgo is effective for relief of PMS symptoms. Natural Medicine Journal (online) 2(3), naturalmedicinejournal.com (accessed 25 June 2019). Salehi B, others. Ginkgo biloba for attention-deficit/hyperactivity disorder in children and adolescents: a double blind, randomized controlled trial. Progress in Neuro-Psychopharmacology and Biological Psychiatry 34:76–80 (2010). Uebel-von Sandersleben H, others. Ginkgo biloba extract EGb 761® in children with ADHD. Zeitschrift fur Kinder - und Jugendpsychiatrie und Psychotherapie 42:337–347 (2014). Shakibaei F, others. Ginkgo biloba in the treatment of attention-deficit/hyperactivity disorder in children and adolescents. A randomized, placebo-controlled trial. Complementary Therapies in Clinical Practice 21 (2):61-67 (2015).
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The Multivitamin Quality Check: Are You Missing Vital Nutrients? Part 2
In Part 1, we looked at the high-quality vitamins contained in BrainMD's premier multiple vitamin-mineral supplement, NeuroVite Plus. In addition to NeuroVite Plus' potent vitamins, this robust multiple also offers many essential minerals needed for optimal brain and body health. The Essential Minerals of NeuroVite Plus Certain minerals are built into the structures of enzymes and are essential for their activity. These are the essential minerals, of which NV supplies all but two. Iron can be dangerous when combined with other nutrients so must be taken separately. Copper also has this capability and is rarely deficient since it is relatively abundant in the diet. NV's mineral ingredients are carefully selected for both safety and optimal health benefit. Magnesium and Calcium are both essential for health, and they have a yin-yang relationship by which each helps balance the actions of the other. This formula supplies calcium and magnesium in forms that are most readily absorbed and best tolerated. Unlike other multiples, NV avoids using oxide forms since these are very poorly absorbed. Calcium is needed only in small amounts in the brain, heart and other "soft" organs, is relatively abundant in the diet, and high intakes can pose a safety risk. Magnesium helps counterbalance any negative effects from calcium, and is needed wherever calcium is needed (including in the formation of bone), so that calcium supplements should always include magnesium. Magnesium is required by practically all the body's 300 energy-related enzymes so is needed for our cells to make energy. Yet the surveys consistently find at least 1 in 2 Americans may be deficient in this mineral. Magnesium is fundamental to the brain's electrical activity via the nerve cell synapse connections. It is also crucial for many other functions including healthy heart rhythm and other muscle functions. Iodine is essential for the thyroid gland to make hormones that control our metabolic thermostats for energy generation and overall activity levels, all through life. Thyroid hormones are crucial for the brain and body to develop, and iodine deficiency is the greatest cause of mental retardation worldwide. In the U.S. and other countries, declines in consumption of dairy, eggs and iodized salt and exposures to environmental pollutants are linked to widespread iodine deficiency in women of reproductive age with potential catastrophic consequences once they become pregnant. Zinc is essential for at least 100 enzymes, and for healthy development of the brain and other organs. All our cells need zinc to maintain the structure of their DNA and the actions of their genes. Zinc is structurally built into the enzyme superoxide dismutase (SOD), which is our first line of defense against free radical toxins. This mineral is also urgently needed during pregnancy and for childhood development, sexual maturation, and male fertility. Selenium is required by at least 25 enzymes and other selenium proteins, which are foundational to life and are important for brain development. Selenium enzymes also provide antioxidant defense against toxins. Selenium enzymes help keep our genes working optimally, regulate production of the thyroid hormones that help control our energy levels, and also regulate muscle development, heart muscle function, and immunity. Manganese is needed for the major antioxidant enzyme SOD2 (superoxide dismutase 2), localized within the mitochondria to help control potentially harmful oxygen free radicals. This mineral works along with selenium in enzymes that are our cells' primary defense against toxins. All our organs need manganese in order to process cholesterol, carbohydrates, and amino acids, and to produce tissue matrix components called proteoglycans. Chromium is essential for healthy blood sugar metabolism. This formula provides it as chromium picolinate, which is very well absorbed, helps in coping with carbohydrate cravings, and supports healthy mood management. In a clinical trial by Krikorian and colleagues, this chromium ingredient even improved brain activity in older adults. Molybdenum is required by at least five detoxifying enzymes that work closely with the antioxidant enzymes. Among their other functions, molybdenum enzymes help neutralize sulfites and bisulfites, potentially toxic substances generated by the body’s normal sulfur metabolism. Molybdenum enzymes also help detoxify the sulfites and bisulfites that are often sprayed onto foods as preservatives, and added into wines, vinegars, even medical products. The Proprietary Brain Boosting Blend This blend's hefty 575 milligram daily allowance provides: PhosphatidylSerine (PS), the only nutrient granted two Qualified Health Claims by the U.S. FDA, related to its brain benefits. PS has over 35 double-blind clinical trials and is proven useful for attention in children as well as for memory in adults. Acetyl-L-Carnitine (ALC, aka acetyl l carnitine), fuels energy generation by the mitochondria, and supplies acetyl groups for the brain to make the important neurotransmitter acetylcholine. ALC's acetyl groups to help regulate their gene activity. Alpha-Lipoic Acid (ALA), a conditionally-essential nutrient vital for energy. ALA is a structural component of three of our most major energy enzymes. ALA is also a powerful antioxidant. Clinical trials indicate it enhances nerve cell energy, maintenance and repair. Coenzyme Q10 (CoQ), another conditionally essential nutrient vital for energy, and also a powerful antioxidant. CoQ is an essential cofactor and protectant for the mitochondria of our cells, which generate over 90 percent of all our energy. Additional Important Nutrients Choline is an essential nutrient and source of vital methyl groups. Choline's methyl groups back up the methyls from dietary methylfolate and methyl B12. Choline readily enters the brain to promote the production of acetylcholine, our most abundant nerve transmitter. As a methyl backup, choline helps ensure healthy gene functions and is crucial for liver functions. Lutein and Zeaxanthin are carotenoid nutrients essential for vision and eye health, and recent research indicates they also can enhance brain function. Very few multiples provide them. They are mostly present in leafy-green and yellow-red vegetables, and surveys indicate many people aren't getting enough from their foods. These nutrients are practically vitamins, since the body can't make them and we have to get them from our diet. NeuroVite Plus also is designed to promote healthy blood flow to the brain. The brain needs very substantial blood flow to provide it with sufficient oxygen and the other nutrients it needs. Resveratrol is a plant polyphenol clinically found to promote blood flow. Pterostilbene is chemically related to resveratrol and complements its actions. Hesperidin Flavonoid Complex provides antioxidants that protect the delicate blood vessel walls. Boron is likely an essential mineral and is known to support healthy brain function. It also supports the body's utilization of vitamin D and magnesium, both very important for maintenance of brain health. Silicon supports renewal of the connective tissues that build the tissue matrix glue in the brain and other organs. The Organic Fruit and Vegetable Blend Individuals who don't manage to consume the optimal amounts of fruits and veggies every day - that's practically all of us - get help from this formulation. It provides the antioxidant and numerous other health benefits of wild blueberries, broccoli sprouts, tomatoes, spinach, acai, carrots, strawberries, and alfalfa sprouts. The Digestive Enzyme Blend This plant-derived enzyme blend includes lipase, amylase, lactase, cellulase and protease, which are all able to tolerate chemical stresses while helping us digest our foods. NeuroVite Plus provides vitamins for memory - and a whole lot more, including mood, attention, learning, behavior, and the functioning of all our organs. BrainMD monitors ongoing research to ensure NV's ingredients are optimal for individuals of all ages. NV is essential to overall health and well-being. Key Scientific References U.S. Department of Health and Human Services and U.S. Department of Agriculture. 2015-2020 Dietary Guidelines for Americans, 8th Edition. 2015: https://health.gov (accessed 20 May 2019). Blumberg JB, others. Contribution of dietary supplements to nutritional adequacy by socioeconomic subgroups in adults of the United States. Nutrients 10, 4; doi:10.3390/ nu10010004 (2018). Ames BN. Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. PNAS (Proceedings National Academy of Sciences US) 103 (47):17589-17594 (2006). Harrison FE, May JM. Vitamin C function in the brain. Free Radicals in Biology and Medicine 46 (6): 719-730 (2009). Pilz S, others. Vitamin D and mortality. Anticancer Research 26:1379-1388 (2016). Douaud G, others. Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment. PNAS (Proceedings National Academy of Sciences US) 110 (23):9523-9528 (2013). Reynolds EH. Methylfolate as adjunctive treatment in major depression. American Journal of Psychiatry 170(5), 560 (2013). Botto LD, Yang Q. 5, 10-methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. American Journal of Epidemiology 151:862-877 (2000). Wallace TC, others. Choline: The underconsumed and underappreciated essential nutrient. Nutrition Today 53(6):240-253 (2018). Kidd P. Magnesium: cornerstone of nutritional health insurance. Natural Products Insider 2019 Mar 20:7 pages. https://www.naturalproductsinsider.com/vitamins-minerals/magnesium-cornerstone-nutritionalhealth-insurance. Gower-Winter SD, Levenson CW. Zinc in the central nervous system: From molecules to behavior. Biofactors 38(3):186-193 (2012). Krikorian R, others. Improved cognitive-cerebral function in older adults with chromium supplementation. Nutritional Neuroscience 13(3):116-122 (2010). Panth P, others. A review of iodine status of women of reproductive age in the USA. Biological Trace Element Research 188:208-220 (2019). Renzi-Hammond LM, others. Effects of a lutein and zeaxanthin intervention on cognitive function: a randomized, double-masked, placebo-controlled trial of younger healthy adults. Nutrients 9, 1246: doi:10.3390/nu9111246 (2017). Kidd P. The most proven nutrient for memory and brain health: phosphatidylserine (PS). https://www.brainmd.com > HOME > BRAIN HEALTH blog, Nov 21, 2018. Di Stefano G, others. Acetyl-l-carnitine in painful peripheral neuropathy: A systematic review. Journal of Pain Research 12:1341-1351 (2019). Tibullo D, others. Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential. Inflammation Research DOI 10.1007/s00011-017-1079-6 (2017). Qu H, others. Effects of coenzyme Q10 on statin-induced myopathy; an updated meta-analysis of randomized controlled trials. Journal of the American Heart Association 2018: e009835 (2018).
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