Weight Management

Promotes healthy body composition when combined with diet and exercise

Blood Sugar Balance

Supports healthy blood sugar and insulin level

Digestion

Promotes healthy digestion

Craving Support

Helps balance cravings and promotes healthy weight management

Supplement Facts
Serving Size 1 Capsule Servings Per Container 60
Amount Per Serving		% DV
Oleoylethanolamide (from Carthamus tinctorius L.) (Seed)	125 mg	†
Berberine Blend [Berberine (from Berberine HCl (Berberis aristata) (Bark)), Dihydroberberine (from Berberis vulgaris) (Rhizome)]	99.5 mg	†
Other Ingredients: Rice bran, hydroxypropyl methylcellulose, silica, vegetable magnesium stearate.

Soy Free
No Animal Products

Month 1

Clinically studied nutrients get to work

Month 2-3

Nutritional deficiencies are corrected (varies by person)

Month 4 & Beyond

Amplify the benefits & support long-term health

Berberine

99.5 mg

Berberine is renowned for its physiological impact on the body's metabolism and has been used for years in traditional Ayurvedic and Chinese medicine. Derived from benzylisoquinoline alkaloids found in medicinal plants, it stands out as a highly promising natural aid for metabolic issues. Smart Metabolic Burn is formulated with berberine HCl and dihydroberberine (DHB), the most effective and bioavailable forms of this powerful, botanical compound.*

Oleoylethanolamide

125 mg

Oleoylethanolamide (OEA) is a novel substance in the field of weight management. The compound works in conjunction with existing OEA in the intestine to reduce overall food intake and stimulate lipolysis, the breakdown of triacylglycerols into free fatty acids and glycerol. Studies show that the role OEA plays in weight loss is based on activation of peroxisome proliferator-activated receptor-α, which reduces blood lipid levels and enhances peripheral fatty acid breakdown.*

Say Goodbye To Frustration, Say Hello To Results

Tired of trying every weight loss solution without seeing results? Stuck in a weight loss plateau? Constantly battling thoughts about food? Wondering if there's a breakthrough product or natural appetite suppressant that can finally work for you?

Don't waste your time on fads, gimmicks, or social media trends; empower yourself and transform your health with a science-backed approach to metabolic wellness.

Burn Fat & Balance Glucose Levels With Berberine

Smart Metabolic Burn is clinically formulated for sustainable weight control.^* By targeting inflammation and decreasing oxidative stress, Smart Metabolic Burn addresses the root cause of weight-related challenges.^*

• OUR CEO SAYS •

“This all-new nutritional supplement combines the power of two potent compounds – berberine and oleoylethanolamide (OEA) – to prime your body for metabolic wellness. It acts like a natural appetite suppressant that activates fat-burning and is clinically formulated to support healthy weight management."

- Daniel G. Amen, MD

Optimize Your Body's Natural Fat-Burning Potential

Berberine is renowned for its physiological impact on the body's metabolism and has been used for years in traditional Ayurvedic and Chinese medicine.^* Derived from benzylisoquinoline alkaloids found in medicinal plants, it stands out as a highly promising natural aid for metabolic issues.^* Unlike other berberine supplements, Smart Metabolic Burn is formulated with berberine HCl and dihydroberberine (DHB), the most effective and bioavailable forms of this powerful, botanical compound.^*

Berberine Benefits

The benefits of a berberine supplement are wide-ranging. Taking the dose offered in Smart Metabolic Burn, can help:

Decrease abdominal fat and waist to hip ratio^*
Activate AMP-activated protein kinase (AMPK) to combat visceral fat^*
Regulate blood sugar levels^*
Support digestive health^*
Promote cardiovascular health^*
Provide nutritional support for women experiencing hormonal or age-related issues^*

The Revolutionary Power Of OEA

In addition to berberine, Smart Metabolic Burn also harnesses the power of the powerful compound oleoylethanolamide (OEA) to reduce appetite and enhance metabolism.^*

Recognized in the scientific community as a novel approach to weight management, OEA works synergistically in the body to reduce overall food intake and stimulate lipolysis – the breakdown of triacylglycerols into free fatty acids and glycerol.^*

OEA: The Secret To Satiety & Weight Loss

Studies show that OEA's role in weight loss is rooted in the activation of peroxisome proliferator-activated receptor-α, which reduces blood lipid levels and helps break down unhealthy visceral fat, especially around the abdomen.^*

Only 2 Capsules Daily

Smart Metabolic Burn goes beyond ordinary berberine supplements. Just two capsules a day can kickstart your metabolism, fight body fat (especially unhealthy abdominal fat), and support healthy weight management.^*

Who Can Benefit From Smart Metabolic Burn?

If you’re seeking support for metabolic, cardiovascular, and GI health, struggling with cravings and overeating, or trying to maintain healthy blood sugar levels, Smart Metabolic Burn may offer the support you need.^* Clinical studies conducted with women experiencing age-related issues show promise for better weight management, reduced oxidative stress, and support for age-related complications in women.

Clinically Researched Benefits

As a company firmly rooted in science, we use only clinically researched ingredients that create real results. Here are some of the benefits of taking BrainMD’s Smart Metabolic Burn:

Supports metabolic health^*
Reduces oxidative stress^*
Promotes healthy blood sugar levels and insulin sensitivity^*
Supports metabolism of fat in the liver^*
Maintains healthy cholesterol and triglyceride levels^*
Supports a healthy inflammatory response within the body^*
Benefits body composition when paired with diet and exercise^*

References

Hu, Y., Ehli, E. A., Kittelsrud, J. M., Ronan, P. J., Munger, K. A., Downey, T., Bohlen, K., Callahan, L., Munson, V., Jahnke, M., Marshall, L. L., Nelson, K. P., Huizenga, P., Hansen, R. J., Soundy, T. J., & Davies, G. E. (2012). Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine, 19(10), 861–867. https://doi.org/10.1016/j.phymed.2012.05.009.
Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Berberine improves insulin sensitivity by inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic syndrome patients. Evid Based Complement Alternat Med. 2012;2012:363845. doi: 10.1155/2012/363845. Epub 2012 Mar 8. PMID: 22474499; PMCID: PMC3310165.

How do I take Smart Metabolic Burn?

It’s recommended for adults to take one capsule twice per day, approximately 30 minutes before a meal.

How does this supplement support my insulin regulation?

Can this supplement make me dependent on it, or addicted?

Does this product have any side effects?

Is this product safe to take during pregnancy?

What other BrainMD supplements work well with Smart Metabolic Burn?

Does this product contain any allergens?

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Smart Metabolic Burn

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Key Benefits

Weight Management

Blood Sugar Balance

Digestion

Craving Support

Supplement Facts

Soy Free

No Animal Products

What to expect

Ingredients

Say Goodbye To Frustration, Say Hello To Results

• OUR CEO SAYS •

- Daniel G. Amen, MD

Optimize Your Body's Natural Fat-Burning Potential

The Revolutionary Power Of OEA

Only 2 Capsules Daily

Clinically Researched Benefits

References

Frequently Asked Questions

Which Supplements Should You Be Taking?

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