Meet Vitamin D3 + K2: The Potent Pairing of Essential Vitamins You Need Daily
Medically Reviewed by Dr. Nicole Avena

Vitamins and minerals are essential for our survival.

Our foods should be providing the energy we need to power our brain and body, but ongoing population surveys indicate the standard American diet is failing to do this job.

Among the many vitamins most of us aren’t getting enough of daily are vitamins D3 and K2.

Vitamin D3 Basics

Vitamin D is primarily known for building bones. However, healthy vitamin D3 levels also can help support your mood, boost your brain function, and generally improve your well-being.

Sometimes referred to as the sunshine vitamin, vitamin D3 promotes the actions of serotonin, dopamine, and other key brain neurotransmitters. It’s involved in the healthy regulation of thousands of human genes and is crucial for a strong immune system.

After it’s made in the skin as vitamin D3 (cholecalciferol), it becomes converted by the liver and kidney into a hormone (calcitriol) that has receptors in practically all our tissues. D3 is so important to brain function that its receptors are distributed throughout the brain. This powerful hormone also helps regulate the heart, circulation, gut, liver, pancreas, immune system, and other organ systems.

Vitamin D3 is critical for a healthy pregnancy. It also plays a critical role in the brain’s early development, its ongoing maintenance, and its functions that underlie healthy mood and basic cognition, such as learning and making memories.

Vitamin K2 Basics

Vitamin K’s positive actions for the brain and body are frequently underestimated. Vitamin K2, as menaquinone-7 (MK-7), is much more active than vitamin K1. K2 activates brain proteins that not only help control calcium’s potential to do damage, but also support brain cell maturation, survival, and electrical conduction.

Outside the brain, uncontrolled calcium can form stony deposits in the heart valves, large arteries, and elsewhere in the body. Vitamin K2 proteins help direct calcium away from the brain, heart, blood vessels, and other soft tissues and towards the bone, teeth, and nails that need it. K2 also is essential for the coagulation processes required for healthy wound healing.

Better Together: Benefits of Vitamin D3 + K2

When combined with vitamin K2, vitamin D3 helps move calcium into your bones (where it’s needed most), which prevents it from forming deposits in your arteries and blood vessels.

One randomized controlled trial conducted with postmenopausal women who suffered from weak and brittle bones found that after 2 years of supplementation with vitamin D3, vitamin K2, or both, the women who received both vitamin D3 and K2 experienced better bone mineral density compared to the other groups that took only vitamin D3 or vitamin K2.

From this and other research, it seems that vitamins D3 and K2 can provide greater benefit together than what each nutrient offers individually.

That’s why BrainMD is proud to offer this unique vitamin tandem in its new nutraceutical formulation…

Vitamin D3 + K2 | BrainMD

Vitamin D3 + K2: Synergistic Support for Your Heart, Bones & Brain

Vitamin D3 (cholecalciferol) and vitamin K2 (MK-7) are two fat-soluble vitamins that work together to strengthen bones, promote normal blood clotting, and maintain a healthy heart and arteries.* Together, these vitamins work to combat an unhealthy inflammatory response and protect against serious illness and cognitive decline.*

Here are some of the benefits of taking Vitamin D3 + K2:

  • Supports a healthy immune system*
  • Promotes cognitive function*
  • Builds healthy bones*
  • Antioxidant protection*
  • Cardiovascular support*
  • Better blood flow and circulation*

Also, Vitamin D3 + K2 was developed for optimized bioavailability and absorption.*

Who Can Benefit from Vitamin D3 + K2?

Several groups of individuals can benefit from taking vitamins D3 and K2, including:

Middle-aged and Elderly Individuals – Current clinical evidence suggests that a moderate to high vitamin K status can help prevent the onset and progression of age-related illness. Vitamin K has been shown to help against oxidative stress by blocking the generation of reactive oxygen species. Both vitamins D3 and K2 have been shown to decrease frailty in aging populations.

Post-Menopausal Women – Due to the hormone changes that occur during menopause, women are more at risk for developing weak or brittle bones. The hormone oestrogen is an essential hormone for bone health. After menopause, oestrogen levels can fall and lead to a decrease in bone mass density. Supplementing with vitamin K2 can help inhibit bone loss in postmenopausal women.

Anyone with Low Vitamin D Status – Adequate vitamin D3 is especially important for people who have less access to regular sunlight, live in regions where winters are dark and cold, or have been diagnosed with vitamin D deficiency. For these individuals, and anyone seeking to maintain a healthy D3 status, supplementation is incredibly important. Work with your physician to get your D3 levels checked, which will allow them to recommend an appropriate daily D3 dosage for you.

Vitamin D3 + K2 Ingredients

Vitamin D3 + K2 contains a dynamic duo of clinically tested ingredients that help provide vital nutrients for your brain and body.*

These ultra-pure nutrients are:

Vitamin D3

Vitamin D3 (cholecalciferol) is a fat-soluble vitamin needed by nearly every cell in the body to function and thrive. It helps regulate the immune system, aids in calcium absorption, balances mood, and promotes optimal health. Although the body produces vitamin D naturally when exposed to sunlight, research suggests that up to 95% of American adults are not getting enough, so supplementation is often recommended.

Vitamin K2

The most potent form of vitamin K is vitamin K2 as menaquinone-7 (MK-7). This vitamin activates proteins that support brain cell maturation, survival, and electrical conduction. Vitamin K2 promotes the coagulation mechanisms needed for healthy wound healing. It also helps ensure that calcium will only form hard deposits in the bones, teeth and nails – not in the heart, blood vessels, brain and other soft tissues where they can cause harm.

Vitamin D3 + K2 FAQ

How do I take Vitamin D3 + K2?

Adults 18 and older are recommended to consume 1 capsule daily – this provides 125 mcg (5000 IU) of vitamin D as cholecalciferol and 180 mcg of vitamin K as MK-7. These dosages have been researched and shown to be effective in clinical trials. The dose and form of the vitamins provided in this supplement ensures adequate coverage across different adult populations. To maximize absorption, it’s best to take this supplement in combination with a meal or snack containing healthy fat (olive oil, avocado, coconut oil, etc.).

Can this supplement make me dependent on it, or addicted?

No. Like other BrainMD products, this is a dietary supplement, not a drug, and is not habit-forming.

Is this supplement beneficial for brain health?

Yes. Both vitamins D3 and K2 have been shown to help support a healthy brain. Vitamin D3 + K2 is an excellent addition to other BrainMD supplements to aid in healthy aging and cognitive functioning.*

Is this product safe to take during pregnancy?

Yes, these vitamins are safe to take during pregnancy. However, it’s best to work with your healthcare provider to determine the appropriate dosage.

Are there any allergens in Vitamin D3 + K2?

These capsules are free from dairy, sugar, soy, nuts, eggs, yeast, and contain no artificial colorings or flavorings. They’re also gluten free and non-GMO.

D3 + K2 = 1 Powerful Supplement

This unique supplement combination – vitamin D3 as cholecalciferol and vitamin K2 as MK-7 – can help prevent vitamin deficiency (especially during winter months), fight oxidative stress, promote normal blood clotting, and support a healthy immune system.*

These two powerful, fat-soluble vitamins also work synergistically to promote strong bones, healthy cognitive functioning, and maintain a healthy circulatory system.*

Try Vitamin D3 + K2 today!


At BrainMD, we’re dedicated to providing the highest purity nutrients to improve your physical health and overall well-being. For more information about Vitamin D3 + K2 and our full list of brain healthy supplements, please visit us at BrainMD.

*These statements have not been evaluated by the FDA. This content is for informational purposes only. It is not meant to substitute for medical or healthcare advice from a physician, nor is it intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning a new health regimen.

Keith Rowe